Results 101 to 110 of about 3,449 (222)

Assessment of Platelet Storage Lesions, Viability, and Function in Canine Platelet Concentrate Units Stored at 4°C for 14 Days

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To assess platelet function, storage lesion development, and bacterial contamination in canine platelet concentrate (PC) units stored at 4°C for 14 days. Design Prospective, in vitro experimental study. Setting University teaching hospital. Animals Six units of canine PC.
Kate S. Farrell, Steven E. Epstein, Nghi Nguyen, Ronald H. L. Li   +3 more
wiley   +1 more source

Studies of platelet antibodies at MacKay Memorial Hospital in Taiwan: Methods, case reviews and a possible case of post‐transfusion purpura

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Platelet antibody screening and identification are crucial and challenging. MacKay Memorial Hospital has been dedicated to this for nearly four decades. We reviewed our experience with platelet antibody detection methods and prevalence, and presented a possible case of post‐transfusion purpura caused by anti‐CD36 ...
Chiang Chen‐Yu, Chang Hsiao‐Lin, Chan Yung‐Shu, Cheng Wern‐Cherng, Lin Marie   +4 more
wiley   +1 more source

Evaluation of the platelet cross-matching in oncology patients

Global Journal of Transfusion Medicine, 2016
Context: Platelet transfusion is an essential part of managing cancer. Refractoriness to platelet transfusion poses great challenge in the treatment of thrombocytopenic patients.
Sadhana Mangwana, Nikhil Simon
doaj   +1 more source

Investigating human platelet antigens and antibodies in pregnancy: An 11‐year experience from a Canadian reference laboratory

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Foetal and neonatal alloimmune thrombocytopaenia (FNAIT) is a potentially severe immune‐mediated condition that is believed to be under‐identified in the Canadian population. The Canadian Blood Services National Platelet Immunology Reference Laboratory (NPIRL) serves as a centralized referral laboratory for FNAIT ...
Bryan Tordon, Gwen Clarke, Jacqueline Wong, Ann Peregrin, Akash Gupta   +4 more
wiley   +1 more source

First platelet transfusion refractoriness in a patient with acute myelocytic leukemia: A case report. [PDF]

World J Clin Cases, 2023
Tu SK, Fan HJ, Shi ZW, Li XL, Li M, Song K.   +5 more
europepmc   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, Volume 30, Issue 3, Page 389-396, June 2026.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Differences in Perspectives and Policies Regarding End‐of‐Life Care Between Hematologists and Gastroenterologists

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Patients with hematologic malignancies often receive aggressive treatment until the terminal phase and transition to end‐of‐life (EOL) care less frequently than those with solid tumors. A 2015 survey compared hematologists' and solid tumor‐oncologists' attitudes toward EOL care, revealing differences.
Takuya Matsunaga, Kazuyuki Murase, Shiro Hinotsu, Kohichi Takada, Takanori Teshima, Ken Sato, Yasuhiro Nagaoka, Takayuki Machino, Yusuke Sugama, Masayoshi Kobune, Kunihiko Ishitani   +10 more
wiley   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

Improved bilirubin reduction with therapeutic plasma exchange and haemoperfusion in a dog with immune‐mediated haemolytic anaemia

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 6‐year‐old spayed female Golden Retriever mix was diagnosed with immune‐mediated haemolytic anaemia. Initial treatments included immunosuppression and blood transfusions. With acute mentation decline and rapid increase in serum bilirubin, therapeutic plasma exchange (TPE) was initiated.
Natasha S. Yeh, Kay Drake, Michael T. Kato   +2 more
wiley   +1 more source

Distribution for platelet antibody in patients with immune-mediated platelet transfusion refractoriness

Hematology
Objectives: HLA Class I, HPA (Human platelet antigen), CD36 allo/isoantibodies, and platelet glycoprotein autoantibodies are the primary causes of immune-mediated platelet transfusion refractoriness (iPTR).
Bing Zhang, Kairong Ma, Xinyu Huang, Xiaozhen Hong, Ying Liu, Zhipan Wu, Xianguo Xu, Faming Zhu   +7 more
doaj   +1 more source