Results 201 to 210 of about 48,011 (239)

Platelet Transfusion Refractoriness: Controversial Issues

Clinical Medicine Review, 2018
Javier Marco, Pilar Solves
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Platelet Refractoriness Evaluation after Platelet Concentrate Transfusion in Pediatric Leukemia

Research Journal of Pharmacy and Technology, 2021
Platelet transfusion is being used in 67%-75% of hematology malignancies including leukemia. Platelet refractoriness is the failure to achieve satisfactory responses to platelet transfusions.
Ana Murtasyidah, B. A. Tambunan, Mia Ratwita Andarsini   +2 more
semanticscholar   +1 more source

Refractory Response to Platelet Transfusion Therapy

Journal of Infusion Nursing, 2010
Platelet transfusions are commonly used for prophylaxis and treatment of bleeding. After a transfusion, an increment or "boost" is expected to occur. While a number of factors can contribute to a poor posttransfusion increment, refractoriness is typically defined as failure to achieve an appropriate increment after receiving 2 consecutive transfusions ...
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ABH antibodies causing platelet transfusion refractoriness

Transfusion, 1986
Two alloimmunized patients with multispecific anti‐HLA and high‐titered ABH antibodies showed transfusion failures after ABH‐mismatched HLA‐identical platelet transfusions, whereas ABH‐matched HLA‐identical platelets showed sufficient increments. The anti‐A and ‐B could be demonstrated on platelets by immunofluorescence tests using FITC‐labeled goat ...
A, Brand, K, Sintnicolaas, F H, Claas, J G, Eernisse   +3 more
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Refractoriness to Platelet Transfusions in Children with Acute Leukemia

Journal of Pediatric Hematology/Oncology, 1995
We evaluated the incidence of clinically significant refractoriness to platelet transfusions in children with acute leukemia.We reviewed the complete transfusion records up to July 1993 of all 213 patients diagnosed with acute leukemia at our institution over the 4-year period 1987 to 1990.
J, DeCoteau, S, Haddad, V, Blanchette, A, Poon   +3 more
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Diagnosis and management of refractoriness to platelet transfusion

Blood Reviews, 2001
Improvements in the availability and quality of platelet transfusions have markedly reduced the morbidity and mortality associated with intensive myelosuppressive therapy. Alloimmunization and refractoriness to platelet transfusion remains a significant clinical problem, although the incidence of alloimmunization may be declining due to more widespread
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Antileukocyte Antibodies in Patients Refractory to Platelet Transfusions

American Journal of Clinical Pathology, 1979
Sera from 12 multitransfused patients who were refractory to random-donor platelets were tested for lymphocytotoxic and leukoagglutinating antibodies using panel cells from various volunteers whose HLA-A and -B antigens were known. All sera contained leukoagglutinins reactive with cells from at least one panel member, whereas only 33% had ...
B R, MacPherson, R G, Westphal
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Alloimmunization and Refractoriness to Platelet Transfusions

Laboratory Medicine, 1992
Refractoriness to platelet transfusions due to alloimmunization is one of the most serious complications that can occur for a chronically transfused platelet recipient. Although the diagnosis and management of this condition are difficult, the available therapeutic choices are increasing. The increasing use of family and human leukocyte antigen–matched
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Transfusion of ABO‐mismatched platelets leads to early platelet refractoriness

British Journal of Haematology, 1990
Summary. Forty‐three consecutive patients previously unexposed to platelets and undergoing treatment for acute leukaemia or autografting for relapsed Hodgkin's lymphoma were randomized to receive transfused platelets of either their own ABO group (OG) or of a major mismatched group (MMG).
R, Carr, J L, Hutton, J A, Jenkins, G F, Lucas, N W, Amphlett   +4 more
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Platelet Transfusion Refractory Patients

2009
Publisher Summary This chapter focuses on an inappropriately low platelet count defined as platelet refractory, which develops following repeated platelet transfusions. The cause for platelet refractoriness is mentioned to be both non-immune and immune and etiology is often multifactorial.
Jeanne E. Hendrickson, John D. Roback
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