Results 21 to 30 of about 291,220 (220)

Research progress on prevention strategies for immune platelet transfusion refractoriness

Zhongguo shuxue zazhi
Platelet transfusion refractoriness (PTR) is a common issue among patients with hematological diseases and tumors. This article reviews the diagnostic criteria, influencing factors, and recent prevention and management strategies for immune PTR.
ZHAO Peizhe, XU Yi, LIANG Yajun, LI Qing, ZHOU Yuan, XU Xianguo   +5 more
doaj   +2 more sources

Platelet HLA gene bank digital matching technology for platelet transfusion refractory patients with malignant tumors: a case report [PDF]

Frontiers in Oncology
The platelet human leucocyte antigen (HLA) gene bank contains the genetic information of HLA loci in a large number of blood donors. Currently, the most effective treatment for platelet transfusion refractoriness (PTR) is to evaluate the probability of ...
Xiang Gao, Jianhua Li, Xiuwen Ni, Lijun Wang, Peilin Hu, Xiaowei Zhu   +5 more
doaj   +2 more sources

Distribution for platelet antibody in patients with immune-mediated platelet transfusion refractoriness

Hematology
Objectives: HLA Class I, HPA (Human platelet antigen), CD36 allo/isoantibodies, and platelet glycoprotein autoantibodies are the primary causes of immune-mediated platelet transfusion refractoriness (iPTR).
Bing Zhang, Kairong Ma, Xinyu Huang, Xiaozhen Hong, Ying Liu, Zhipan Wu, Xianguo Xu, Faming Zhu   +7 more
doaj   +2 more sources

Risk Factors of Platelet Refractoriness After Thrombocyte Concentrate Transfusion in Pediatric Acute Leukemia [PDF]

, 2022
Children with acute leukemia often require platelet transfusions, but the platelet count frequently doesn't reach a satisfactory response, which is known as platelet refractoriness. This study aimed to analyze the risk factors for platelet refractoriness
Hosea, M. K. (Mellisa), Wardhani, A. N. (Adwina), Ugrasena, I. D. (I), Andarsini, M. R. (Mia), Larasati, M. C. (Maria), Cahyadi, A. (Andi)   +5 more
core   +2 more sources

Mechanism and transfusion strategy of immunogenic platelet transfusion refractoriness

Zhongguo shuxue zazhi, 2022
Platelet transfusion is an irreplaceable method to treat patients with platelet reduction in Hematology Department and Oncology Department. However, immunogenic platelet transfusion refractoriness is a huge challenge to patients who require repeatedly ...
Juan SAI, Li TIAN
doaj   +1 more source

Efficacy of apheresis and concentrated platelets under different transfusion strategies

Zhongguo shuxue zazhi, 2022
Objective To retrospectively analyze the clinical effects of apheresis and concentrated platelets under different transfusion strategies, so as to explore more scientific transfusion strategies.
Meihong CHEN, Jiafu HUANG
doaj   +1 more source

Establishment and evaluation of predictive models of platelet transfusion effect in multi-center tumor patients

Zhongguo shuxue zazhi, 2023
Objective To study the platelet transfusion predictive models in tumor patients and evaluate its application effect. Methods A retrospective study was conducted on 944 tumor patients, including 533 males and 411 females who received platelet transfusion ...
Gang ZHAO, Fan GUO, Qing LI, Yihua XIE, Jun LI   +4 more
doaj   +1 more source

Prevalence and Factors associated with Platelet Refractoriness among Tanzanian Patients – A Cross-Sectional Study from The National Reference Hospital [PDF]

, 2023
Background A response to platelet transfusion is assessed by post transfusion platelet increment and failure to reach a desired increment is termed platelet refractoriness, which is best measured by the corrected count increment (CCI) which takes into ...
Luhulla, Koga Malunguja, Nasser, Ahlam, Chamba, Clara, Kakumbula, Helen, Iversen, Per Ole   +4 more
core   +1 more source

Factors affecting the efficacy of platelet transfusion and specificity of HLA-Ⅰ antibodies in tumor patients

Zhongguo shuxue zazhi, 2023
Objective To analyze the factors affecting the efficacy of platelet transfusion and the specificity of HLA-Ⅰ antibodies in tumor patients. Methods Tumer patients applied for platelet transfusion from November 2019 to July 2021 in Sichuan Cancer Hospital ...
Juan SAI, Shanshan WAN, Li TIAN
doaj   +1 more source

Platelet compatibility and platelet antibodies detection: A step towards resolving dilemma in management of platelet refractoriness in oncology patients

Global Journal of Transfusion Medicine, 2019
Background: Platelet refractoriness complicates the provision of platelet transfusions- a critical and essential part in management of thrombocytopenia in Oncology patients. Platelet refractoriness poses challenge due to alloimmunization to HLA (Class I)
Sadhana Mangwana, Atin Kacker, Nikhil Simon   +2 more
doaj   +1 more source