Results 31 to 40 of about 269,068 (254)

Management of patients refractory to platelet transfusion [PDF]

open access: yesLeukemia, 2001
Abstract Objective.—To present a current assessment and practical approach to the diagnosis and management of patients who are refractory to platelet transfusions. Design.—A task force was convened by the College of American Pathologists under the auspices of the Transfusion Medicine Resource Committee for the purposes of outlining current concepts in ...
openaire   +2 more sources

Transfusion effect of 0.5-dose of apheresis platelet in pediatric patients

open access: yesZhongguo shuxue zazhi, 2023
Objective To investigate the transfusion effect of 0.5-dose of apheresis platelet in pediatric patients. Methods A total of 195 children who underwent 0.5-dose platelet transfusion from August 2021 to June 2022 were enrolled, and the platelet count ...
Lijuan QIU   +3 more
doaj   +1 more source

Immune-mediated platelet transfusion refractoriness in a severely thrombocytopenic patient with myelodysplastic syndrome successfully treated with romiplostim

open access: yes, 2022
Immune-mediated platelet transfusion refractoriness due to anti-human leukocyte antigen (HLA) antibodies can occur in approximately 9% of patients with myelodysplastic syndromes (MDS) and can lead to an increased risk of clinically relevant bleeds ...
Čengić, Marina   +9 more
core   +1 more source

Evaluation of the effectiveness of platelet crossmatching by the solid‐phase red cell adherence assay in adult patients of a tertiary care hospital in Thailand: A retrospective study

open access: yesHealth Science Reports, 2022
Background and Aims Platelet transfusion refractoriness is well aware to be associated with poor clinical outcomes. Patients with the alloantibody causing refractoriness required cross‐matched compatible products to improve the platelet number.
Thunnakhon Sinwatcharaphirom   +2 more
doaj   +1 more source

Current trends in platelet transfusions practice: The role of ABO-RhD and human leukocyte antigen incompatibility

open access: yesAsian Journal of Transfusion Science, 2015
Platelet transfusions have contributed to the revolutionary modern treatment of hypoproliferative thrombocytopenia. Despite the long-term application of platelet transfusion in therapeutics, all aspects of their optimal use (i.e., in cases of ABO and/or ...
Serena Valsami   +4 more
doaj   +1 more source

Management of Patients Refractory to Platelet Transfusion

open access: yesArchives of Pathology & Laboratory Medicine, 2003
Abstract Objective. —To present a current assessment and practical approach to the diagnosis and management of patients who are refractory to platelet transfusions. Design. —A task force was convened by the College of
Ronald A, Sacher   +5 more
openaire   +2 more sources

Establishment of platelet donor registry improves the treatment of platelet transfusion refractoriness in Guangzhou region of China

open access: yes, 2010
Platelet transfusion refractoriness (PTR) is the major complication of long-term platelet supportive care. To improve the effectiveness of platelet transfusion therapy in PTR patients, we aimed to establish a platelet donor registry in our region ...
Xu, Xiuzhang   +9 more
core   +1 more source

Budget impact of implementing platelet pathogen reduction into the Italian blood transfusion system

open access: yes, 2018
Background. Despite improvements in blood donor selection and screening procedures, transfusion recipients can still develop complications related to infections by known and emerging pathogens. Pathogen reduction technologies (PRT) have been developed to
Rebulla, Paolo   +11 more
core   +1 more source

Human Leukocyte Antigen Alloimmunization and Alloimmune Platelet Refractoriness

open access: yes, 2020
Despite significant advancements in the production of platelet products, storage, and transfusion, transfusion refractoriness remains a significant clinical problem, affecting up to 14% of hematological patients receiving platelet transfusions.
Anno Saris   +3 more
core   +1 more source

An Evaluation of Platelet Transfusion Response Using HLA Crossmatch-compatible Donors in Patients with Platelet Refractoriness [PDF]

open access: yes, 2009
Background : Majority of immune-mediated platelet refractoriness is caused by HLA alloimmunization and can be effectively managed by HLA-matched platelet transfusions. However, HLA class I-typed large-sized donor registry has not been well established in
박경득   +6 more
core   +1 more source

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