Results 61 to 70 of about 5,003 (295)

Current and novel biomarkers in cardiogenic shock

European Journal of Heart Failure, EarlyView.
A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end‐organ dysfunction.
Victor Galusko, Florian A. Wenzl, Christophe Vandenbriele, Vasileios Panoulas, Thomas F. Lüscher, Diana A. Gorog   +5 more
wiley   +1 more source

Polyinosinic: polycytidylic acid induced inflammation enhances while lipopolysaccharide diminishes alloimmunity to platelet transfusion in mice

Frontiers in Immunology, 2023
IntroductionAlloimmune responses against platelet antigens, which dominantly target the major histocompatibility complex (MHC), can cause adverse reactions to subsequent platelet transfusions, platelet refractoriness, or rejection of future transplants ...
Johnson Q. Tran, Johnson Q. Tran, Marcus O. Muench, Marcus O. Muench, Betty Gaillard, Orsolya Darst, Mary M. Tomayko, Mary M. Tomayko, Rachael P. Jackman, Rachael P. Jackman   +9 more
doaj   +1 more source

Permeability and conductivity of platelet-reinforced membranes and composites [PDF]

, 2001
We present large scale simulations of the diffusion constant $D$ of a random composite consisting of aligned platelets with aspect ratio $a/b>>1$ in a matrix (with diffusion constant $D_0$) and find that $D/D_0 = 1/(1+ c_1 x + c_2 x^2)$, where $x= a v_f/b$ and $v_f$ is the platelet volume fraction.
arxiv   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Suction tube uterine tamponade versus uterine balloon tamponade for treatment of refractory postpartum hemorrhage: A randomized clinical feasibility trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare low‐cost “Suction Tube Uterine Tamponade” (STUT) treatment for refractory postpartum hemorrhage (PPH) with uterine balloon tamponade (UBT) using a randomized feasibility study. Methods After verbal assent, we allocated participants with refractory PPH by randomly ordered envelopes to STUT or routine UBT at 10 hospitals in ...
Mandisa Singata‐Madliki, Albaro J. Nieto‐Calvache, Luisa F. Rivera Torres, Hazmath Abdul, Joanne Batting, Sylvia N. Cebekhulu, Lawrence Chauke, Priya Soma‐Pillay, Susan Fawcus, Logie Govender, Busiwe Majeke, Xolani Mbongozi, Katrin Middleton, Poovangela Naidoo, Sanele Ndaba, Trevi Spence, Gaynor M. Balie, Angelica Monroy, Monica Cantor, G. Justus Hofmeyr   +19 more
wiley   +1 more source

A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation

Haematologica, 2018
HLA antibodies are associated with refractoriness to platelet transfusion, leading to rapid platelet clearance, sometimes coinciding with clinical side effects such as fever and chills.
Maaike Rijkers, Anno Saris, Sebastiaan Heidt, Arend Mulder, Leendert Porcelijn, Frans H.J. Claas, Ruben Bierings, Frank W.G. Leebeek, A.J. Gerard Jansen, Gestur Vidarsson, Jan Voorberg, Masja de Haas   +11 more
doaj   +1 more source

Donor HLA Genotyping using Polymerase Chain Reaction- Sequence Specific Primers (PCR-SSP) as Method for Acquiring Donor Panel in Platelet Refractoriness

MCBS (Molecular and Cellular Biomedical Sciences), 2021
Background: Evaluation and identification of HLA antibodies in the recipient’s serum is of utmost importance prior to transplantation and transfusion. HLA typing is a steppingstone in proposing a donor panel. In order to obtain the HLA typing, Polymerase
Tubagus Djumhana Atmakusuma, Andhika Rachman, Ni Ken Ritchie   +2 more
doaj   +1 more source

Effects of Average Number of Platelets Through the Thickness and Platelet Width on the Mechanical Properties of Discontinuous Fiber Composites [PDF]

arXiv, 2023
In this study, we experimentally and numerically investigate the evolution of the tensile material properties of Discontinuous Fiber Composites (DFCs) with an increasing average number of platelets through the thickness for two different platelet widths.
arxiv  

Ask a pathologist [PDF]

, 2015
QUESTION: My patient has thrombocytopenia, but after the last platelet transfusion his platelet count only increased from 21,000/μL to 26,000/μL.
Coberly, Emily
core  

Cost analysis of intrauterine balloon tamponade versus uterine artery embolization in the management of persistent postpartum hemorrhage

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The aim of this study was to compare the cost of a strategy initially resorting to intrauterine balloon tamponade versus a strategy initially resorting to uterine artery embolization in the management pathway of persistent postpartum hemorrhage.
Lisanne R. Bonsen, M. Elske van den Akker‐van Marle, Camila Caram‐Deelder, Paul I. Ramler, Christianne J. M. de Groot, Thijs Urlings, Thomas van den Akker, Johanna G. van der Bom, Dacia D. C. A. Henriquez, on behalf of the TeMpOH‐1 study group   +9 more
wiley   +1 more source