Results 61 to 70 of about 3,822 (260)

Re-Evaluation Of Modified Rapid Monoclonal Antibody Immobilization Of Platelet Antigen (MR-MAIPA) For Detecting Platelet Antibody In Patients With Suspected Immune Thrombocytopenia [PDF]

, 2016
Ujian antibodi terhadap platelet di Malaysia hanya dijalankan di Pusat Darah Negara (PDN), Kuala Lumpur. Sebelum tahun 2013, ujian antibodi terhadap platelet di Malaysia dijalankan menggunakan teknik MAIPA. Namun begitu, MAIPA memerlukan masa selama tiga
Aziz, Mohd Fahmi
core  

The diagnostic performance of the basic versus the detailed telomere Flow FISH test in young patients with aplastic anaemia

British Journal of Haematology, EarlyView.
Summary Identifying telomere biology disorders (TBDs) in patients with aplastic anaemia (AA) is essential for guiding appropriate care. Telomere length (TL) measurement by flow cytometry with fluorescence in situ hybridization supports diagnosis, but the real‐world performance of the basic test (lymphocytes and granulocytes) versus the detailed test ...
Nicholas F. DeCleene, Duc T. Nguyen, Susan E. Kirk, Hannah L. Helber, Ghadir S. Sasa, Alison A. Bertuch   +5 more
wiley   +1 more source

Management of Patients Refractory to Platelet Transfusion

Archives of Pathology & Laboratory Medicine, 2003
AbstractObjective.—To present a current assessment and practical approach to the diagnosis and management of patients who are refractory to platelet transfusions.Design.—A task force was convened by the College of American Pathologists under the auspices of the Transfusion Medicine Resource Committee for the purposes of outlining current concepts in ...
Ronald A, Sacher, Thomas S, Kickler, Charles A, Schiffer, Laurence A, Sherman, Arthur W, Bracey, Ira A, Shulman   +5 more
openaire   +2 more sources

Ask a pathologist [PDF]

, 2015
QUESTION: My patient has thrombocytopenia, but after the last platelet transfusion his platelet count only increased from 21,000/μL to 26,000/μL.
Coberly, Emily
core  

Phase II study of the triple combination of rabbit ATG, ciclosporin and eltrombopag in patients with transfusion‐dependent aplastic anaemia: West Japan Hematology Study Group (W‐JHS) AA02 trial

British Journal of Haematology, EarlyView.
Summary The efficacy of a triple combination of rabbit anti‐human thymocyte immunoglobulin (rATG), ciclosporin and eltrombopag (EPAG) was prospectively evaluated in patients with severe or transfusion‐dependent non‐severe aplastic anaemia (SAA) across 29 institutions in Japan. Sixty patients were enrolled, of whom 48 had SAA. The primary end‐point, the
Fumi Nakamura, Ken Ishiyama, Ritsuro Suzuki, Hiroyuki Maruyama, Yasushi Onishi, Kensuke Usuki, Hideo Koh, Katsuto Takenaka, Ryunosuke Saiki, Seishi Ogawa, Kana Matsumoto, Takuto Takahashi, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Kenichi Yoshimura, Itaru Matsumura, Koichi Akashi, Shinji Nakao   +17 more
wiley   +1 more source

Research progress on the pathogenesis, prevention and treatment of immune platelet transfusion refractoriness

Zhongguo shuxue zazhi
Platelet transfusion refractoriness (PTR) is one of the common problems in platelet transfusion, significantly impacting patient clinical outcomes and increasing the demand for allogeneic platelet transfusion.
LI Penghui, WU Chenggao, LE Aiping
doaj   +1 more source

A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation

Haematologica, 2018
HLA antibodies are associated with refractoriness to platelet transfusion, leading to rapid platelet clearance, sometimes coinciding with clinical side effects such as fever and chills.
Maaike Rijkers, Anno Saris, Sebastiaan Heidt, Arend Mulder, Leendert Porcelijn, Frans H.J. Claas, Ruben Bierings, Frank W.G. Leebeek, A.J. Gerard Jansen, Gestur Vidarsson, Jan Voorberg, Masja de Haas   +11 more
doaj   +1 more source

Simultaneous flow cytometric detection of antibodies against platelets, granulocytes and lymphocytes [PDF]

, 1991
We present a time-saving and objective flow cytometric immunofluorescence assay for the simultaneous detection of antibodies against platelets, granulocytes or lymphocytes using a reconstituted mixture of these cell populations.
Bolhuis, R.L.H. (Reinder), Gratama, J.W. (Jan-Willem), Linden, R. (Reinier) van der, Sintnicolaas, K. (Krijn), Vries, W. (Walter) de   +4 more
core   +1 more source

International Practices in Managing Preconception, Pregnancy and Childbirth in Women With Glanzmann Thrombasthenia: A Survey From the European Association of Haemophilia and Allied Disorders (EAHAD)

Haemophilia, EarlyView.
ABSTRACT Background Glanzmann thrombasthenia (GT) is an inherited platelet disorder resulting in severely reduced platelet aggregation and increased bleeding tendency. Pregnancy and childbirth in women with GT present significant challenges for both mother and child.
Karlijn H. G. Rutten, Roger E. G. Schutgens, Roseline d'Oiron, Mathieu Fiore, Giancarlo Castaman, Keith Gomez, Mary Mathias, Michelle Lavin, Petra Elfvinge, Rezan Abdul Kadir, Karin P. M. van Galen, the Glanzmann Thrombasthenia and Women and Girls with Bleeding Disorders Working Groups of the EAHAD   +11 more
wiley   +1 more source

The international, prospective Glanzmann Thrombasthenia Registry: treatment and outcomes in surgical intervention

Haematologica, 2015
Standard treatment for Glanzmann thrombasthenia, a severe inherited bleeding disorder, is platelet transfusion. Recombinant factor VIIa is reported to be effective in Glanzmann thrombasthenia with platelet antibodies and/or refractoriness to platelet ...
Man-Chiu Poon, Roseline d’Oiron, Rainer B. Zotz, Niels Bindslev, Matteo Nicola Dario Di Minno, Giovanni Di Minno   +5 more
doaj   +1 more source