Plateletpheresis-associated lymphopenia in frequent platelet donors [PDF]
Abstract More than 1 million apheresis platelet collections are performed annually in the United States. After 2 healthy plateletpheresis donors were incidentally found to have low CD4+ T-lymphocyte counts, we investigated whether plateletpheresis causes lymphopenia.
John M. Gansner +19 more
openaire +2 more sources
Associations between dietary iron and zinc intakes, and between biochemical iron and zinc status in women [PDF]
Iron and zinc are found in similar foods and absorption of both may be affected by food compounds, thus biochemical iron and zinc status may be related. This cross-sectional study aimed to: (1) describe dietary intakes and biochemical status of iron and ...
Bailey, Karl B. +7 more
core +2 more sources
Background: Platelet transfusions are routinely needed as an essential part of treatment for patients undergoing cancer therapy, as well as for those with bleeding disorders, and for patients undergoing open heart surgeries or organ transplantation.
Imran Khurshid, Irm Yasmeen, Aleem Jan
doaj +1 more source
Plateletpheresis adverse events in relation to donor and plateletpheresis session profile
Introduction: Increasing demand of platelet transfusions for patients has led to a trend in the increased use of automated blood collections. These share many of the same reactions and injuries seen with pooled platelets obtained from whole blood donation but also have unique complications.
Rajni Bassi +2 more
openaire +2 more sources
HIV Activates the Tyrosine Kinase Hck to Secrete ADAM Protease-Containing Extracellular Vesicles [PDF]
HIV-Nef activates the myeloid cell-typical tyrosine kinase Hck, but its molecular role in the viral life cycle is not entirely understood. We found that HIV plasma extracellular vesicles (HIV pEV) containing/10 proteases and Nef also harbor Hck, and ...
Baur, A. S. +8 more
core +2 more sources
Research progress of iron deficiency in apheresis donors
Objective The loss of iron stores is well documented in whole blood donors, and a large number of studies have confirmed that blood donors are at risk of iron deficiency.
Guanglin XIAO +3 more
doaj +1 more source
Abstract Background Trauma is the most common cause of death in children >1 year of age, with hemorrhage being the most common preventable cause of death after injury. Antifibrinolytics like tranexamic acid (TXA) are a key aspect of trauma management in children, but optimal dosing remains unknown.
Gideon Stitt +5 more
wiley +1 more source
Adverse events associated with apheresis procedures: incidence and relative frequency
Background: Apheresis procedures [plateletpheresis, plasmapheresis, peripheral blood stem cell collection] are usually well tolerated. Occasionally Adverse Events (AEs) of variable severity may occur during or after the procedure. AEs that occur in Donor/
P Sujatha +2 more
doaj +1 more source
Early prediction of transfusion requirements in trauma patients using explainable machine learning
Abstract Introduction Hemorrhagic shock is the most common preventable cause of death in trauma patients. Early transfusion significantly improves survivability in patients suffering from hemorrhagic shock. We hypothesized that machine learning models could reduce time to initial transfusion by more rapidly identifying patients likely to require blood ...
Michael R. De La Rosa +4 more
wiley +1 more source
Study and analysis of the coagulation factors and their natural inhibitors levels in apheresis derived platelet concentrate units over a five-day storage period [PDF]
Background: The possibility of utilizing clotting factors in the plasma phase of apheresis platelet concentrates, as a supplement to the standard FFP transfusion for clotting factor replacement needs to be explored.
Bhowmik, Sujay +3 more
core +2 more sources

