Results 1 to 10 of about 4,437,433 (360)

Effects of anesthetics on cardiac function test in mouse model of pressure overload-induced heart failure

陆军军医大学学报, 2022
Objective To compare the effects of four common anesthetics on cardiac function test in pressure overload-induced heart failure mice. Methods Eight-week-old male C57/BL6 mice (n=120) with a body weight of 20~25 g were selected to establish a mouse model ...
TANG Fuqin, REN Meiying, ZHU Yu, JIAN Zhao, XIAO Yingbin   +4 more
doaj   +1 more source

Prolonged low flow reduces reactive hyperemia and augments low flow mediated constriction in the brachial artery independent of the menstrual cycle [PDF]

, 2013
© 2013 Rakobowchuk et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
AE Devan, AM Malek, B Jiang, CM Pedersen, DHJ Thijssen, Emily R. Parsloe, Emma Harris, GP Fadini, J Pleiner, Karen M. Birch, KE Pyke, LE Spieker, M Rakobowchuk, Mark Rakobowchuk, MI Okorie, MW Broadhead, Nick Ashton, RA Harris, RK Kharbanda, Sarah E. Gibbins, SP Loukogeorgakis, SP Loukogeorgakis, SP Loukogeorgakis, T Gori, T Gori, T Gori, T Gori, TL Weissgerber   +27 more
core   +11 more sources

Hypermethylation of the CTRP9 promoter region promotes Hcy induced VSMC lipid deposition and foam cell formation via negatively regulating ER stress

Scientific Reports, 2023
To provide a theoretical basis for the prevention and treatment of atherosclerosis (As), the current study aimed to investigate the mechanism underlying the effect of homocysteine (Hcy) on inducing the lipid deposition and foam cell formation of the ...
Xiuyu Wang, Xing Ma, Yue Zeng, Lingbo Xu, Minghao Zhang   +4 more
doaj   +1 more source

Cooperation between NSPc1 and DNA methylation represses HOXA11 expression and promotes apoptosis of trophoblast cells during preeclampsia

Acta Biochimica et Biophysica Sinica, 2023
Accumulating evidence has shown that the apoptosis of trophoblast cells plays an important role in the pathogenesis of preeclampsia, and an intricate interplay between DNA methylation and polycomb group (PcG) protein-mediated gene silencing has been ...
Xie Lin, Ding Ning, Sheng Siqi, Zhang Honghong, Yin He, Gao Lina, Zhang Hui, Ma Shengchao, Yang Anning, Li Guizhong, Jiao Yun, Shi Qing, Jiang Yideng, Zhang Huiping   +13 more
doaj   +1 more source

miR-30a-5p promotes glomerular podocyte apoptosis via DNMT1-mediated hypermethylation under hyperhomocysteinemia

Acta Biochimica et Biophysica Sinica, 2021
Abnormal elevation of homocysteine (Hcy) level is closely related to the development and progression of chronic kidney disease (CKD), with the molecular mech2anisms that are not fully elucidated.
Ding Ning, Xie Lin, Ma Fei, Ma Shengchao, Xiong Jiantuan, Lu Guanjun, Zhang Huiping, Jiang Yideng   +7 more
doaj   +1 more source

A novel lncRNA FPASL regulates fibroblast proliferation via the PI3K/AKT and MAPK signaling pathways in hypertrophic scar

Acta Biochimica et Biophysica Sinica, 2022
Hypertrophic scar is a problem for numerous patients, especially after burns, and is characterized by increased fibroblast proliferation and collagen deposition.
Ma Fang, Shen Jiangyong, Zhang Hui, Zhang Zhenghao, Yang Anning, Xiong Jiantuan, Jiao Yun, Bai Zhigang, Ma Shengchao, Zhang Huiping, Jiang Yideng   +10 more
doaj   +1 more source

Warfare Vascular Injuries [PDF]

Medical Journal Armed Forces India, 2010
Vascular injuries as a part of combat injuries have been recorded since times immemorial. Responsible for death due to exsanguination, the management of vascular injuries was ligation or amputation till the landmark Vietnam experience. The present day management has evolved with advances in modern technology and may start at the battlefield with the ...
R, Katoch, Rps, Gambhir
openaire   +2 more sources

Physiological and pathological characteristics of vascular endothelial injury in diabetes and the regulatory mechanism of autophagy

Frontiers in Endocrinology, 2023
Vascular endothelial injury in diabetes mellitus (DM) is the major cause of vascular disease, which is closely related to the occurrence and development of a series of vascular complications and has a serious negative impact on a patient’s health and ...
Hanyu Liu, Xueru Wang, Hong Gao, Hong Gao, Chan Yang, Chunguang Xie, Chunguang Xie   +6 more
doaj   +1 more source

Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury [PDF]

, 2015
AIMS: Neuropilins 1 and 2 (NRP1 and NRP2) play crucial roles in endothelial cell migration contributing to angiogenesis and vascular development. Both NRPs are also expressed by cultured vascular smooth muscle cells (VSMCs) and are implicated in VSMC ...
Evans, I, Fields, L, Lowe, V, Mahmoud, M, Mehta, V, Pellet-Many, C, Ruivo, J, Zachary, I   +7 more
core   +8 more sources

LncRNA FPASL suppresses fibroblast proliferation through its DNA methylation via DNMT3b in hypertrophic scar

Acta Biochimica et Biophysica Sinica, 2022
Long noncoding RNAs (lncRNAs) are increasingly being implicated as key regulators of cell proliferation, apoptosis, and differentiation. However, the molecular mechanisms of specific lncRNAs in the context of hypertrophic scar remain largely unclear ...
Wu Kai, Ma Fang, Shen Jiangyong, Zhang Hui, Wan Yu, He Xi, Yang Anning, Xiong Jiantuan, Jiao Yun, Bai Zhigang, Ma Shengchao, Jiang Yideng, Zhang Huiping, Hao Yinju   +13 more
doaj   +1 more source