Results 11 to 20 of about 4,437,433 (360)

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial

open access: yesLancet, The, 2019
Summary Background Tranexamic acid reduces surgical bleeding and decreases mortality in patients with traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain injury (TBI) and can cause brain herniation and death.

semanticscholar   +3 more sources

Mitigation of Radiation Induced Pulmonary Vascular Injury by Delayed Treatment with Captopril [PDF]

open access: yes, 2012
Background and Objective: A single dose of 10 Gy radiation to the thorax of rats results in decreased total lung angiotensin-converting enzyme (ACE) activity, pulmonary artery distensibility and distal vascular density while increasing pulmonary ...
Fish, Brian L.   +5 more
core   +2 more sources

Destabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury

open access: yesEBioMedicine, 2016
Lysophosphatidic acid receptor 1 (LPA1) is a druggable target for treating pulmonary inflammatory diseases. However, the molecular regulation of LPA1 stability, a factor that critically impacts its biological activity, remains largely unknown.
Jing Zhao   +6 more
doaj   +1 more source

Vascular Stem/Progenitor Cells in Vessel Injury and Repair

open access: yesFrontiers in Cardiovascular Medicine, 2022
Vascular repair upon vessel injury is essential for the maintenance of arterial homeostasis and function. Stem/progenitor cells were demonstrated to play a crucial role in regeneration and replenishment of damaged vascular cells during vascular repair ...
Jiaping Tao   +11 more
doaj   +1 more source

Effect of Vitamin C Infusion on Organ Failure and Biomarkers of Inflammation and Vascular Injury in Patients With Sepsis and Severe Acute Respiratory Failure: The CITRIS-ALI Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Experimental data suggest that intravenous vitamin C may attenuate inflammation and vascular injury associated with sepsis and acute respiratory distress syndrome (ARDS). Objective To determine the effect of intravenous vitamin C infusion on
A. Fowler   +35 more
semanticscholar   +1 more source

Role of noncoding RNA in vascular remodelling [PDF]

open access: yes, 2016
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H.   +2 more
core   +1 more source

Clinical characteristics and renal prognosis associated with interstitial fibrosis and tubular atrophy (IFTA) and vascular injury in lupus nephritis biopsies.

open access: yesSeminars in Arthritis & Rheumatism, 2019
BACKGROUND Interstitial fibrosis and tubular atrophy (IFTA) and vascular injury are frequent histologic features of lupus nephritis renal biopsies, but their clinical correlates and prognostic value are not well understood. This cohort study investigated
Cianna L Leatherwood   +9 more
semanticscholar   +1 more source

Platelet signaling--blood's great balancing act [PDF]

open access: yes, 2015
The antagonistic balance between CalDAG-GEFI and RASA3 signaling is critical for the fine-tuning of platelet adhesiveness, both in the circulation and at sites of vascular ...
Bergmeier, Wolfgang, Stefanini, Lucia
core   +2 more sources

Major vascular injury during gynecologic cancer surgery

open access: yesGynecologic Oncology Reports, 2021
Objective: Vascular injury during major gynecologic cancer surgery is a rare but potentially fatal complication. The purpose of this study was to review our experience with major vascular injury during gynecologic cancer surgery.
Andrea L. Buras   +5 more
doaj   +1 more source

Wartime Vascular Injury [PDF]

open access: yesMilitary Medicine, 2018
Wartime vascular injury can be particularly challenging due to the complexity of the case, concomitant injuries, resource limitations, and often lack of expertise of the operating surgeon. The proliferation of vascular shunting has been of particular importance as a damage control surgery technique to restore perfusion and temporize the immediate need ...
Todd, Rasmussen   +6 more
openaire   +2 more sources

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