Results 21 to 30 of about 4,437,433 (360)

Traumatic microbleeds suggest vascular injury and predict disability in traumatic brain injury.

open access: yesBrain : a journal of neurology, 2019
Traumatic microbleeds are small foci of hypointensity seen on T2*-weighted MRI in patients following head trauma that have previously been considered a marker of axonal injury.
Allison D Griffin   +13 more
semanticscholar   +1 more source

Radiation-Induced Endothelial Vascular Injury

open access: yesJACC: Basic to Translational Science, 2018
Summary In radiation therapy for cancer, the therapeutic ratio represents an optimal balance between tumor control and normal tissue complications. As improvements in the therapeutic arsenal against cancer extend longevity, the importance of late effects
B. Venkatesulu   +8 more
semanticscholar   +1 more source

Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]

open access: yes, 2006
It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury

open access: yesNature Communications, 2018
Hyperhomocysteinemia (HHcy) is a risk factor for various cardiovascular diseases. However, the mechanism underlying HHcy-aggravated vascular injury remains unclear.
Tuoyi Li   +14 more
semanticscholar   +1 more source

Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infra-orbital blood-nerve barrier following chronic constriction injury? [PDF]

open access: yes, 2017
BackgroundBlood–nerve barrier disruption is pivotal in the development of neuroinflammation, peripheral sensitization, and neuropathic pain after peripheral nerve injury.
Boucher, Yves   +7 more
core   +4 more sources

AIBP and APOA-I synergistically inhibit intestinal tumor growth and metastasis by promoting cholesterol efflux

open access: yesJournal of Translational Medicine, 2019
Background The roles played by cholesterol in cancer development and progression represent a popular field in the cancer community. High cholesterol levels are positively correlated with the risk of various types of cancer.
Tao Zhang   +6 more
doaj   +1 more source

Extracellular-superoxide dismutase DNA methylation promotes oxidative stress in homocysteine-induced atherosclerosis

open access: yesActa Biochimica et Biophysica Sinica, 2022
In the present study, we investigate the effect of homocysteine (Hcy) on extracellular-superoxide dismutase (EC-SOD) DNA methylation in the aorta of mice, and explore the underlying mechanism in macrophages, trying to identify the key targets of Hcy ...
Ma Shengchao   +10 more
doaj   +1 more source

Sox17 is required for endothelial regeneration following inflammation-induced vascular injury

open access: yesNature Communications, 2019
Repair of the endothelial cell barrier after inflammatory injury is essential for tissue fluid homeostasis and normalizing leukocyte transmigration. However, the mechanisms of endothelial regeneration remain poorly understood.
Menglin Liu   +8 more
semanticscholar   +1 more source

Subclavian vascular injuries

open access: yesJournal of British Surgery, 1987
Abstract This study comprises 228 patients with penetrating injuries of the subclavian vessels. The vein alone was involved in 44 per cent, the artery alone in 39 per cent, and both vessels in 17 per cent. The majority of the victims (61 percent) did not reach the hospital alive, and in those who were operated on the mortality was 15·5 ...
D, Demetriades   +4 more
openaire   +2 more sources

A contemporary, 7‐year analysis of vascular injury from the war in Afghanistan

open access: yesJournal of Vascular Surgery, 2018
Objective: Vascular injury is a leading cause of death and disability in military and civilian trauma. Although a previous interim study defined the distribution of vascular injury during the wars in Iraq and Afghanistan, a contemporary epidemiologic ...
Jigarkumar A. Patel   +4 more
semanticscholar   +1 more source

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