Results 231 to 240 of about 419,372 (309)
PLATELETS AND THE SHWARTZMAN PHENOMENON [PDF]
Jack Levin, Leighton E. Cluff
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sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin+21 more
wiley +1 more source
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu+38 more
wiley +1 more source
EFFECTS OF BACTERIAL ENDOTOXIN ON RABBIT PLATELETS [PDF]
Roger M. Des Prez+2 more
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Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao+15 more
wiley +1 more source
PLATELET PHOSPHATIDES. THEIR FATTY ACID AND ALDEHYDE COMPOSITION AND ACTIVITY IN DIFFERENT CLOTTING SYSTEMS* [PDF]
Aaron J. Marcus+3 more
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This study investigates the metabolic vulnerabilities of glioblastoma (GBM), an aggressive brain tumor. Research demonstrates that iron chelation therapy, in combination with standard chemotherapy, significantly enhances the efficacy of treatment against resistant GBM cells in a 3D tumoroid model.
Meitham Amereh+8 more
wiley +1 more source
In Vitro Thrombosis and Platelet Aggregation in Myocardial Infarction [PDF]
N.G. Ardlie+2 more
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In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang+10 more
wiley +1 more source