Results 241 to 250 of about 432,603 (317)

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Platelet effector functions in inflammation. [PDF]

Res Pract Thromb Haemost
Escaig R, Kreutz L, Kaiser R, Nicolai L.
europepmc   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

Synthesis and applications of 1D and 2D nanoparticles prepared through crystallisation-driven self-assembly. [PDF]

Chem Sci
Yang K, Arno MC.
europepmc   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Value of peripheral blood cell parameters and their derived ratios in predicting intravenous immunoglobulin resistance in Kawasaki disease. [PDF]

Ital J Pediatr
Tang Q, Xu X, Gan C.
europepmc   +1 more source

Bridging the clinical equivalence gap: a nationwide survey on healthcare professionals' perceptions of whole blood-derived versus apheresis platelets in China. [PDF]

Hematol Transfus Cell Ther
Sun TC, Zhang N, Wen YJ, Wu D, Zhang WD, Jia YJ.   +5 more
europepmc   +1 more source

Platelet-Derived Granules and Extracellular Vesicles in Neurodegenerative Diseases: Neurovascular Mechanisms and Clinical Implications. [PDF]

Cells
Lee BK, Yoo JR, Jung YS.
europepmc   +1 more source

Cross-species comparison of platelet proteomes reveals developmentally regulated metabolic and inflammatory changes. [PDF]

Blood Vessel Thromb Hemost
Thom CS, Ma X, Feldman HA, McGrath KE, Maurya P, Fazelinia H, Spruce L, O'Reilly D, El Nems A, Escobar JR, Palis J, Morrell CN, Sola-Visner M, Mager DE, Davenport PE.   +14 more
europepmc   +1 more source

Platelets from early-stage Alzheimer patients show enhanced amyloid binding, an elevated open canalicular system and sex-specific differences in their activation profile. [PDF]

Front Neurol
Donner L, Christl J, Kujovic M, Supprian T, Elvers M.   +4 more
europepmc   +1 more source