Results 261 to 270 of about 432,603 (317)

Platelet calmodulin correlates with platelet turnover

European Journal of Haematology, 1990
Abstract: We measured the calmodulin content in platelets in 13 normal persons and in 62 patients with hematological diseases. The level of platelet calmodulin was higher in patients with idiopathic thrombocytopenic purpura (ITP), systemic lupus erythematosus, myeloproliferative disorders, acute leukemia in a recovery phase, aplastic anemia ...
N, Endoh, H, Oh, K, Itoh, T, Asai, S, Yoshida   +4 more
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Platelets and platelet disorders in Africa

Baillière's Clinical Haematology, 1992
Blood platelets, which are known to play important roles in normal vertebrate biology, are influenced by a variety of factors, the majority of which are acquired. In this chapter, attention is drawn to the need to re-examine one of the old accepted values in haematology, the normal platelet count.
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Platelet aggregation by platelet-clumping substance

Thrombosis Research, 1974
Abstract The platelet-clumping substance isolated from rabbit plasma by the authors aggregated washed rabbit platelets, while ADP did not. The presence of AMP or adenosine did not inhibit the appearance of platelet aggregation induced by the clumping substance.
H, Yamazaki, T, Sano, T, Shimamoto, T, Shimamoto   +3 more
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Platelet Economy (Platelet Survival and Turnover)*

British Journal of Haematology, 1966
Investigators studying blood platelet survival and turnover have used the term ‘thrombo‐kinetics’ to describe the subject, by analogy with the usages of thermodynamics. Inasmuch as these phenomena reflect the interactions and hazards which the platelets encounter while discharging their function in the circulation, we prefer the term ‘platelet economy’
J F, Mustard, H C, Rowsell, E A, Murphy
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Selenium in platelets

Biological Trace Element Research, 1988
Blood and its main components are commonly used to detect states of selenium deficiency. In order to examine whether human platelets are able to provide better or additional information, improvements of the analytical method resulted in surprisingly narrow normal ranges for selenium and other mineral elements using neutron activation analysis (NAA) and
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PLATELETS AS IMMUNOGENS

Vox Sanguinis, 1992
An immune response to human platelet antigens (HPA), as in neonatal alloimmune thrombocytopenia (NAIT) and post-transfusion purpura (PTP), is the exception rather than the rule and evidence is accumulating for the importance of human leucocyte antigen (HLA) class II restriction in this situation.
openaire   +3 more sources

Platelet Formation, Platelet Density and Platelet Ageing

1990
Microscopic examination of both platelets and megakaryocytes shows them to vary widely in size and ultrastructure. This structural diversity was noted by early investigators (Bunting 1909) and interest in its origin and significance has continued to the present day.
K. G. Chamberlain, M. Tong, D. G. Penington   +2 more
openaire   +1 more source

Mechanism and control of platelet-platelet interactions

Microvascular Research, 1972
Abstract With the technique of shadow-casting of whole platelets, it has been possible to observe both the very early events produced on the platelet surface by aggregating agents and what appears to be the entire process of platelet aggregation. It has been shown that a variety of aggregating agents and conditions such as ADP, thrombin, collagen ...
François M. Booyse, Thomas P. Hoveke, Donna Kisieleski, Max E. Rafelson   +3 more
openaire   +1 more source

Platelet substitutes and novel platelet products

Expert Opinion on Investigational Drugs, 2000
Despite many advances in the safety, processing and storage of conventional 22 degrees C liquid-stored allogeneic platelet concentrates, there are still significant drawbacks to standard platelet concentrates used in transfusions for patients with thrombocytopenia.
D H, Lee, M A, Blajchman
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Platelet Activity in Washed Platelet Concentrates

Anesthesia & Analgesia, 2004
Life-threatening anaphylaxis or febrile nonhemolytic transfusion reactions after transfusion of platelet concentrates (PCs) is a serious clinical problem caused by the sensitizing of recipients to plasma components, such as immunoglobulin A, or by cytokines. There is a possible indication for washing of PCs in these thrombocytopenic patients.
Schoenfeld H, Muhm M, Doepfmer U, Exadaktylos A, Radtke H   +4 more
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