A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device [PDF]
, 2019 Background and objectives: Several sources of haematopoietic stem cells have been used for static culture of megakaryocytes to produce platelets in vitro.
Baruch, Dominique +5 more
core +1 more source
Neonatal platelet physiology and implications for transfusion
Platelets, 2022 The neonatal hemostatic system is different from that of adults. The differences in levels of procoagulant and anticoagulant factors and the evolving equilibrium in secondary hemostasis during the transition from fetal/neonatal life to infancy, childhood,
Francisca Ferrer-Marín +1 more
doaj +1 more source
Frozen and cold-stored platelets: reconsidered platelet products
Platelets, 2022 Platelet transfusion, both prophylactic and therapeutic, is a key element in modern medicine. Currently, the standard platelet product for clinical use is platelet concentrates at room temperature (20–24°C) under gentle agitation.
Teresa Jimenez-Marco +4 more
doaj +1 more source
Quantitative structural mechanobiology of platelet-driven blood clot contraction. [PDF]
, 2017 Blood clot contraction plays an important role in prevention of bleeding and in thrombotic disorders. Here, we unveil and quantify the structural mechanisms of clot contraction at the level of single platelets.
Alber, Mark S +3 more
core +2 more sources
Platelets, 2022 Mitochondria regulate intracellular metabolism and are also involved in intercellular transfer in vitro and in vivo, thereby affecting the function of adjacent cells.
Enlin Chen +3 more
doaj +1 more source
Current challenges in platelet transfusion
Platelets, 2022 The supply of platelets for transfusion is a logistical challenge due to the physiology of platelets and current measures of transfusion performance dictating storage at 22°C and a short product shelf-life (
Peter Smethurst, Rebecca Cardigan
doaj +1 more source
Dynamic Formation of Preferentially Lattice Oriented, Self Trapped Hydrogen Clusters [PDF]
arXiv, 2023 A series of MD and DFT simulations were performed to investigate hydrogen self-clustering and retention in tungsten. Using a newly develop machine learned interatomic potential, spontaneous formation of hydrogen platelets was observed after implanting low-energy hydrogen into tungsten at high fluxes and temperatures.
arxiv
Platelets, 2022 We analyze changes in circulating platelets in COVID-19 positive patients who received conventional treatment Dexamethasone and Enoxaparin (Dexa-Enoxa) compared to patients treated with conventional therapy plus nebulization with alkaline hypertonic ...
Oscar Salva +6 more
doaj +1 more source
Three-dimensional Multiscale Model of Deformable Platelets Adhesion to Vessel Wall in Blood Flow [PDF]
, 2013 When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering and rolling on the injured endothelium is a critical initial step in blood clot formation.
arxiv +1 more source
Effects of Average Number of Platelets Through the Thickness and Platelet Width on the Mechanical Properties of Discontinuous Fiber Composites [PDF]
arXiv, 2023 In this study, we experimentally and numerically investigate the evolution of the tensile material properties of Discontinuous Fiber Composites (DFCs) with an increasing average number of platelets through the thickness for two different platelet widths.
arxiv