Results 81 to 90 of about 1,229,988 (286)
Online Terrorist Speech, Direct Government Regulation, and the Communications Decency Act [PDF]
, 2018 The Communications Decency Act (CDA) provides Internet platforms complete liability protection from user-generated content. This Article discusses the costs of this current legal framework and several potential solutions.
Beale, Steven
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Innovation and SustainabilityThis article examined the institutional transformations induced by the digital economy, with particular emphasis on their behavioural and strategic implications for economic governance.
H. Bazetska, K. Mykhailova
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Characteristics of the European Platform Regulation
Public Governance, Administration and Finances Law Review, 2022 This paper presents the European regulation of platforms. In its first part, it reconstructs the process by which the concept of ‘platform’ in information technology and marketing have evolved and become a legal concept. This emerged from the mid-2010s, first in amendments of sectoral rules and later in sui generis platform rules.
openaire +2 more sources
Activity regulation for the participative creation of data on-line [PDF]
, 2010 International audienceThis paper discusses automatic regulation in participative Web systems. We present a generic solution with an original trace-centered approach.
Courtin, Christophe +2 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Platforms, Power, and the Antitrust Challenge: A Modest Proposal to Narrow the U.S.-Europe Divide [PDF]
, 2019 Big platforms dominate the new economy landscape. Colloquially known as GAFA [Google, Amazon, Facebook, and Apple] or FAANG [Facebook, Amazon, Apple, Netflix, and Google], the high tech big data companies are charged with using the power of their ...
Fox, Eleanor M.
core +1 more source
Export Control Regulations in the United Arab Emirates - Comparative Analysis with the United Kingdom [PDF]
, 2019 Governments across the world appreciate the need for checks on the transfer or exportation of commodities, information, software, and technology considered of strategic value.
Malkawi, Bashar H.
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source