Results 101 to 110 of about 1,248,661 (307)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Determination of Cholesterol Oxidation Products in Meat Products by Saponification at Room Temperature Combined with Gas Chromatography-Quadrupole-Time-of-Flight Mass Spectrometry [PDF]

Shipin Kexue
In view of the diverse forms and unstable properties of cholesterol oxidation products (COPs) in meat products under specific conditions, a sample pretreatment technology, saponification at room temperature, was established for the accurate detection of ...
LI Jie, CHEN Qianqian, WANG Yanli, TIAN Qiyan, LIANG Xiuqing, LI Xia, LI Xinling, LIU Yanming, SHEN Zhonglan
doaj   +1 more source

Characteristics of the European Platform Regulation

Public Governance, Administration and Finances Law Review, 2022
This paper presents the European regulation of platforms. In its first part, it reconstructs the process by which the concept of ‘platform’ in information technology and marketing have evolved and become a legal concept. This emerged from the mid-2010s, first in amendments of sectoral rules and later in sui generis platform rules.
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Empathic mediators for distance learning courses [PDF]

, 2018
Conferência Internacional realizada em Lisboa de 15-16 de novembro de 2018.Online distance learning introduces several challenges, such as the dependence of online tools, the asynchronous communication between teachers and students, and the lack of ...
Alves, Catarina Bilé, Barros, Daniela Melaré Vieira, Carmo, Maria Beatriz, Carvalho, Elizabeth, Cláudio, Ana Paula, Costa, Ricardo, Marcos, Adérito, Martinho, Carlos, Morgado, Leonel, Morgado, Lina, Rocio, Vitor, Rodrigues, Ricardo, Seixas, Sónia, Silva, João Balsa da, Varghese, Anila Ann   +14 more
core  

Pattern Recognition: Industry seeking regulation – the case of crowdfunding. Bruges Political Research Papers 79/2020 [PDF]

, 2020
At first it seems counterintuitive that an industry would seek regulation over itself, but from the point of view of crowdfunding, it was a logical step.
Ambrus, Eva
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Procompetitive infrastructure sector regulation and diffusion of innovation: The case of broadband networks [PDF]

The paper assesses the scope for competition inducing infrastructure regulation in furthering the diffusion of innovation. The paper uses data on the adoption of broadband services comprising a global panel of 167 countries.
Gruber, Harald, Koutroumpis, Pantelis
core  

Synergy between theory and practice for ultra large container ships [PDF]

, 2010
In 2003 an accessibility study based on real-time simulations for the S-class container ships of Maersk Sealand was performed at Flanders Hydraulics Research in cooperation with all involved parties (public and port authorities, pilots, tug and shipping ...
Eloot, Katrien, Vantorre, Marc, Verwilligen, Jeroen   +2 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source