Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
MAS platforms as an enabler of enterprise mobilisation: The state of the art [PDF]
One of the main application areas for multi-agent systems technology is enterprise mobilization, wherein the main business process actors are nomadic workers.
Lee, L +4 more
core +2 more sources
Platform-Enabled Destination Management: KPI Dashboards and DEA Benchmarking in the Peloponnese
Platform-enabled governance is reshaping destination management, yet subnational destinations still lack replicable dashboards that combine key performance indicators (KPIs) with efficiency analysis.
Georgios Tsoupros +3 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Platforms, network effects and small business dynamics in China : case study of the Shanzhai cell phone industry [PDF]
This paper seeks to argue the significance of platforms on emerging markets through a case study of the Shanzhai cell phone industry in Shenzhen, China.
Pan, Jiutang, Ding, Ke
core
Fashion Futures as Design Scenarios for the Triple Transition Framework
This article explores how fashion, as a culture-intensive industry, can act as a testbed for ecosystem-centred sustainability transitions. Building on debates on the Triple Transition (green, digital, resilience) and the four pillars of sustainability ...
Paola Bertola +3 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Two-Sided Platforms: Pricing and Social Efficiency [PDF]
This paper models two-sided market platforms, which connect third-party suppliers (developers) of many different products and services to users who demand a variety of these products.
Andrei Hagiu
core
Trust as Behavioral Architecture: How E-Commerce Platforms Shape Consumer Judgment and Agency
In digital marketplaces, trust in e-commerce platforms has evolved from a protective heuristic into a powerful mechanism of behavioral conditioning. This review interrogates how trust cues such as star ratings, fulfillment badges, and platform reputation
Anupama Peter Mattathil +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

