Results 71 to 80 of about 800,456 (356)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Electrochemical behaviour of gamma hydroxybutyric acid at a platinum electrode in acidic medium [PDF]

, 2013
The electrooxidation of Gamma Hydroxybutyric Acid (GHB) on a polycrystalline platinum electrode is studied by cyclic voltammetry in acidic medium. Two oxidation peaks, A and B, are obtained in the positive scan within the potential range of the double ...
Andrew, Bard, Camargo, Cappell, Ciolino, Crookes, del Colle, Dimos, Elie, Elie, ElSohly, Gahlinger, Heinen, Hitmi, Hitmi, Housmans, Iwasita, J. González-Rodríguez, J.M. Sevilla, Lai, Lamy, Li, Louaagie, M. Blázquez, Ma, Nart, Nart, Palatini, R. Jiménez-Pérez, Richard, Rodriguez, Souto, Sporer, T. Pineda, Wood   +34 more
core   +1 more source

Conflict between work and nonwork roles of employees in the mining industry: Prevalence and differences between demographic groups

SA Journal of Human Resource Management, 2011
Orientation: International researchers have increasingly recognised the interaction between work and nonwork roles as an interesting and important topic.
Betsie Steyl, Eileen Koekemoer
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Synthesis and Characterization of Nanoscale Tungsten Particles with Hollow Superstructure Using Spray Drying Combined with Calcination Process

Nanoscale Research Letters, 2019
Nanoscale tungsten (W) powder is used in some special materials. In this study, a hollow superstructure W powder consisting of nanoparticles was synthesized by spray drying combined with two-step calcination from commercial (NH4)6W7O24·6H2O.
Panchao Zhao, Wei Yi, Qigao Cao, Bosheng Zhang, Kunkun Chen, Rui Dang, Jialin Chen   +6 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Microstructural evolution and nanoindentation creep behavior in a PdAgCuAuPtZn multi-principal elements alloy

Journal of Materials Research and Technology
The precious metal based multi-principal elements alloy (MPEA) PdAgCuAuPtZn is mainly used in electrical contact applications, as a new type of multi-component alloy.
Xuan Zhou, Hualong Ge, Shunmeng Zhang, Li Fu, Zhiwei Xia, Junjie He, Kai Xiong, Jun Cheng, Yi Liu, Lihua Ma, Quan Fu, Zhi Xiong, Yong Mao   +12 more
doaj   +1 more source

Correction to: Synthesis and Characterization of Nanoscale Tungsten Particles with Hollow Superstructure Using Spray Drying Combined with Calcination Process

Nanoscale Research Letters, 2019
In the article [1], the use of the formula (NH4)6W7O24·6H2O to represent the starting material ammonium paratungstate (APT) is outdated and incorrect.
Panchao Zhao, Wei Yi, Qigao Cao, Bosheng Zhang, Kunkun Chen, Rui Dang, Jialin Chen   +6 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Removal of cytostatic platinum compounds and recovery of precious metal from aqueous wastestream [PDF]

, 2013
Over the last decades, a strong antropogenic increase in platinum concentrations in the environment is observed. While catalytic converters used in cars and industry contribute to elevated levels in vegetation and soils, hospitals intensely discard ...
Du Laing, Gijs, Folens, Karel
core   +1 more source