Results 131 to 140 of about 31,406 (294)

Liver transplant recipients with polycystic liver disease have longer waiting times but better long-term clinical outcomes than those with liver disease due to other causes: A retrospective cross-sectional study.

PLoS ONE
IntroductionLiver transplantation is the only curative option for patients with polycystic liver disease (PLD). In the United Kingdom, these patients are listed on the variant syndrome list due to their preserved liver function reflected in the United ...
Matt Gittus, Joanna Moore, Albert C M Ong   +2 more
doaj   +1 more source

Plasma glycosylphosphatidylinositol phospholipase D (GPI-PLD) and abdominal aortic aneurysm.

, 2012
Recent reviews state that a circulating biomarker predicting aortic rupture risk would be a powerful tool to stratify patients with small screen-detected abdominal aortic aneurysm (AAA).
Wallinder, Jonas, Henriksson, Anders E., Bergström, Jörgen, Lindqvist, Markus   +3 more
core  

Unveiling the roles of extracellular vesicles in hematologic malignancies: Pathogenesis, diagnostic tools, and clinical translation

Interdisciplinary Medicine, EarlyView.
Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen, Zhiyuan Wu, Feng Zhang, Yuan Meng, Hongyan Liao, Tony Y. Hu   +5 more
wiley   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source

Outcomes of pharmacist‐led deprescribing interventions in older adults living in long‐term care facilities: a scoping review

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background An increase in the ageing population across long‐term care facilities (LTCFs) has led to an increased risk of polypharmacy. Pharmacist‐led deprescribing (PLD) can reduce these risks but there are limitations to its widespread uptake.
Sefunmi Odetola, Eileen Willis, Katrina Lane‐Krebs, Ashlyn Sahay   +3 more
wiley   +1 more source

Effect of phosphatidylcholine on pld gene expression level of Aspergillus fumigatus by the real time PCR method and investigations of these genes using bioinformatics analysis

Iranian Journal of Microbiology, 2012
Background and Objectives: Phospholipases are a group of enzymes that breakdown phospholipid molecules producing second products. These second products play a diverse role in the cell such as signal transduction and digestion in humans.
Ad Noodeh, N Singh, Gd Robson
doaj  

Inter‐Shot Motion Correction of Segmented 3D‐GRASE ASL Perfusion Imaging With Self‐Navigation and CAIPI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Segmented 3D Gradient and Spin Echo (GRASE) is commonly used in Arterial Spin Labeling (ASL) perfusion imaging. However, it is vulnerable to inter‐shot motion, leading to subtraction errors that cannot be corrected. We developed a retrospective self‐navigated inter‐shot motion correction method for segmented 3D‐GRASE ASL imaging with ...
Minhao Hu, Frederik J. Lange, Peter Jezzard, Joseph G. Woods, Mark Chiew, Thomas W. Okell   +5 more
wiley   +1 more source

Multiple‐TE Based Blood–Brain‐Barrier Water Exchange Time Measurement Using a TE‐Resolved 3D TSE Stack‐Of‐Spirals Readout

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a slice‐wise blurring‐free and densely sampled TE‐resolved multiple‐TE (mTE) ASL sequence (TASL) for measuring blood–brain barrier (BBB) water exchange time. Methods A 3D TSE spiral‐readout pCASL sequence was modified to enable TE‐resolved acquisition.
Bo Li, Yiran Li, Xiao Liang, Amnah Mahroo, Manuel Taso, Marta Vidorreta Díaz de Cerio, Lucas Lemos Franco, Yulin Chang, María Asunción Fernández Seara, Matthias Günther, John A. Detre, Ze Wang   +11 more
wiley   +1 more source

Inhibition of Cell Invasion by Targeting PLD

, 2010
Phospholipase D (PLD) is a crucial signaling enzyme involved in many cellular processes. The catalytic activity of PLD is essential for the production of Phosphatidic Acid (PA), a critical second messenger in cell signaling cascades downstream. Using the
Farkaly, Terry C.
core  

Denoising of ASL Data Using Deep Learning Priors Generated From Distribution Remapping

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop an effective deep learning (DL)–based method to denoise arterial spin labeling (ASL) data. Methods Conventional DL–based ASL denoising methods often suffer from overfitting and poor generalization when training data are limited.
Ziyang Xu, Rong Guo, Ziwen Ke, Yudu Li, Yibo Zhao, Wen Jin, Ruihao Liu, Ziyu Meng, Yao Li, Zhi‐Pei Liang   +9 more
wiley   +1 more source