Results 61 to 70 of about 19,659 (264)
The role of phospholipase D in modulating the MTOR signaling pathway in polycystic kidney disease.
PLoS ONE, 2013 The mammalian target of rapamycin (mTOR) signaling pathway is aberrantly activated in polycystic kidney disease (PKD). Emerging evidence suggests that phospholipase D (PLD) and its product phosphatidic acid (PA) regulate mTOR activity.
Yang Liu +6 more
doaj +1 more source
Bile Acid Recognition by NAPE-PLD [PDF]
ACS Chemical Biology, 2016 The membrane-associated enzyme NAPE-PLD (N-acyl phosphatidylethanolamine specific-phospholipase D) generates the endogenous cannabinoid arachidonylethanolamide and other lipid signaling amides, including oleoylethanolamide and palmitoylethanolamide. These bioactive molecules play important roles in several physiological pathways including stress and ...
Margheritis, E. +9 more
openaire +4 more sources
Optical Signature of Moiré Superlattices Formed by Twisted SrTiO3 Membranes
Advanced Functional Materials, EarlyView.We discover optical signatures from bonded interfaces in twisted SrTiO3 moiré superlattices, including low‐frequency Raman vibrational modes and strong second‐harmonic generation, consistent with strong interlayer coupling inferred from cross‐sectional electron microscopy and ab initio calculations. ABSTRACT Moiré superlattices formed at the interfaces
T. A. M. Ragib Shahriar +13 more
wiley +1 more source
Machine Learning with Probabilistic Law Discovery: a Concise Introduction
Известия Иркутского государственного университета: Серия "Математика", 2023 Probabilistic Law Discovery (PLD) is a logic based Machine Learning method, which implements a variant of probabilistic rule learning. In several aspects, PLD is close to Decision Tree/Random Forest methods, but it differs significantly in how relevant ...
A. V. Demin, D.K. Ponomaryov
doaj +1 more source
Technology mapping for large complex PLDs [PDF]
Proceedings of the 35th annual conference on Design automation conference - DAC '98, 1998 In this paper we present a new technology mapping algorithm for use with complex PLDs (CPLDs), which consists of a large number of PLA-style logic blocks. Although the traditional synthesis approach for such devices uses two-level minimization, the complexity of recently-produced CPLDs has resulted in a trend toward multi-level synthesis.
Jason Helge Anderson, Stephen Dean Brown
openaire +1 more source
Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds
Advanced Functional Materials, EarlyView.This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley +1 more source
Correlated Metal LaNiO3 as a p‐Type Transparent Conductor
Advanced Functional Materials, EarlyView.p‐type transparent conducting oxides are needed to enable superstrate solar cell geometries with n‐type absorbers. The p‐type correlated metal LaNiO3 combines high optical transmission with low electrical resistivity and is compatible with a range of scalable deposition processes.
Shivang Beniwal +8 more
wiley +1 more source
Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery
Advanced Functional Materials, EarlyView.This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar +4 more
wiley +1 more source
Ambient‐Stable Transparent P‐Type CuI Transistors Via Room‐Temperature Pulsed Laser Deposition
Advanced Functional Materials, EarlyView.An in situ PLD fabricated AlOx${\rm AlO}_x$/CuI/AlOx${\rm AlO}_x$ sandwich structure enables stable CuI TFTs with a field‐effect mobility of 2.3 ±$\pm$ 0.7 cm2${\rm cm}^{2}$ V−1${\rm V}^{-1}$ s−1${\rm s}^{-1}$ and excellent ambient stability. Complementary inverters based on CuI:Rb and ZnO:Al exhibit rail‐to‐rail voltage transfer characteristics and an
Yang Chen +5 more
wiley +1 more source
Operando Tracking of Oxygen‐Vacancy Dynamics and Negative Capacitance in Ca‐Doped BiFeO3
Advanced Functional Materials, EarlyView.Operando electrochemical impedance spectroscopy, combined with electrocoloration, enables a direct correlation between real‐space ionic redistribution and the corresponding frequency‐domain electrical response. In lateral Ca‐doped BiFeO3 devices, time‐resolved impedance snapshots capture the evolution from bulk‐dominated mixed conduction to an ...
Jeonghun Suh +3 more
wiley +1 more source