Results 51 to 60 of about 18,976 (183)
Aims Loss of MTAP expression by immunohistochemistry (IHC) is widely used as a surrogate for CDKN2A homozygous deletion (HD) in pleural mesothelioma (PM), but its diagnostic value in peritoneal mesothelioma (PeM) is less well defined. We investigated whether the observed limited reliability of MTAP IHC in PeM reflects a lower frequency of MTAP/CDKN2A ...
Andrea Quaranta +8 more
wiley +1 more source
Cancer Incidence Among Swedish Seafarers Between 1985 and 2020
ABSTRACT Background Several studies from different countries have shown that merchant seafarers have an increased cancer risk compared to the general population. The aim of this study was to provide updated information on cancer incidence in a cohort of Swedish seafarers.
Maria Wallin +3 more
wiley +1 more source
Pleural mesothelioma from fluoro-edenite exposure: PACAP and PAC1 receptor. A preliminary report
Pleural mesothelioma is a devastating malignancy primarily associated with asbestos exposure. However, emerging evidence suggests that exposure to fluoro-edenite fibers, a naturally occurring mineral fiber, can also lead to the development of pleural ...
Claudia Lombardo +8 more
doaj +1 more source
Pleural mesothelioma and venous thrombosis: the eosinophilia link
Peripheral blood eosinophilia and vascular occlusions are rare occurrences in patients with pleural mesothelioma whereas eosinophilia may associate with thrombosis.
Aye Win, Ames Paul
doaj +1 more source
Abstract A 15‐year‐2‐month‐old, male, neutered domestic shorthair cat was presented for a 1‐week history of increased respiratory effort and declining appetite. Point‐of‐care ultrasound diagnosed tri‐cavitary effusion, and echocardiography revealed the presence of multiple free‐floating hyperechoic nodules within the pericardium.
Maximiliane Gabriele Sehn +4 more
wiley +1 more source
Talc Use and Risk of Cancer: An Umbrella Review and Overlapped Analysis
ABSTRACT Background This umbrella review aimed to systematically synthesize and critically appraise the available evidence from systematic reviews and meta‐analyses evaluating the association between talc exposure and cancer risk in humans. Methods This umbrella review was conducted in accordance with the PRIOR guidelines and registered in PROSPERO.
Frank Mayta‐Tovalino +4 more
wiley +1 more source
Next‐Generation CAR‐T Cell Therapy: From Modular Design to Clinical Expansion
Over the past decades, chimeric antigen receptor (CAR)‐T cell therapy has evolved from a linear engineering concept into a powerful yet constrained immunotherapy, limited by tumour microenvironment barriers, immune evasion, and manufacturing complexity.
Yuesong Bai +5 more
wiley +1 more source
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley +8 more
wiley +1 more source
Background Malignant pleural mesothelioma is a rare disease with a poor prognosis; distinguishing it from non-specific pleurisy is essential for determining an appropriate treatment strategy. We aimed to evaluate the diagnostic utility and safety of full-
Takahiro Ueda +13 more
doaj +1 more source
Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma.
To investigate the underlying causes of chemoresistance in malignant pleural mesothelioma, we have studied mesothelioma cell lines as 3D spheroids, which acquire increased chemoresistance compared to 2D monolayers. We asked whether the gene expression of
Dario Barbone +8 more
doaj +1 more source

