Results 11 to 20 of about 42,358 (170)
Pharmacodynamics and pharmacokinetics of PLGA-based doxorubicin-loaded implants for tumor therapy
Drug Delivery, 2022 The traditional systemic chemotherapy through intravenous infusion of doxorubicin (DOX) has many side effects. The aim of this study was to develop a PLGA-based DOX-loaded implant and to evaluate the efficacy and drug metabolism distribution of the ...
Peng He +8 more
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British Journal of Pharmacy, 2023 The aim of the study is to examine the effect of the molecular weight of Polyethylene glycol (PEG) on the properties of nanoparticles. PEGlyation of nanoparticles is a promising approach to extend the circulation time and protect nanoparticles from
HardipSinh Barad +2 more
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PLGA/TiO2 nanocomposite scaffolds for biomedical applications: fabrication, photocatalytic, and antibacterial properties [PDF]
BioImpacts, 2021 Introduction: Porous 3D scaffolds synthesized using biocompatible and biodegradable materials could provide suitable microenvironment and mechanical support for optimal cell growth and function.
Seyedeh Sogol Pelaseyed +3 more
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Influence of PLGA and PLGA-PEG on the dissolution profile of oxaliplatin [PDF]
Polímeros, 2016 Abstract Oxaliplatin was inserted into polymeric matrices aiming to study the interaction of this drug with these polymers and its capability to diffuse to the environment. Tested polymers were: (1) polyethylene glycol (PEG), (2) poly(lactic-co-glycolic acid) (PLGA), and (3) a copolymer of them (PLGA-PEG).
Pereira, Emiliane Daher +8 more
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CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis [PDF]
BioImpacts, 2022 Introduction: The limited efficacy of BCG (bacillus Calmette–Guérin) urgently requires new effective vaccination approaches for the control of tuberculosis. Poly lactic-co-glycolic acid (PLGA) is a prevalent drug delivery system.
Zhengmin Liang +8 more
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Branched PLGA derivatives with tailored drug delivery properties
Acta Pharmaceutica, 2020 Despite several shortcomings such as extreme hydrophobicity, low drug capacity, characteristic triphasic drug release pattern with a high burst effect, poly(lactic-co-glycolic acid derivatives are widely used in drug delivery.
Snejdrova Eva +4 more
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Bioengineering, 2019 Thermoresponsive hydrogels showing biocompatibility and degradability have been under intense investigation for biomedical applications, especially hydrogels composed of hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(lactic acid-co-glycolic
Tomoki Maeda
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Drug Design, Development and Therapy, 2021 Yang Sun, Di Long Department of Orthopaedics, Affiliated Central Hospital of Shenyang Medical College, Shenyang, People’s Republic of ChinaCorrespondence: Yang Sun Email sunyang797979@163.comBackground: The present work is an effort to develop a ...
Sun Y, Long D
doaj
Vaccines, 2019 Formulation of inhalable delivery systems containing tuberculosis (TB) antigens to target the site of infection (lungs) have been considered for the development of subunit vaccines. Inert delivery systems such as poly (lactic-co-glycolic acid) (PLGA) are
Carla B. Roces +4 more
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Cytotoxic and mutagenic potential of juglone: a comparison of free and nano-encapsulated form
Arhiv za Higijenu Rada i Toksikologiju, 2020 Despite its evidenced beneficial herbicidal, antibacterial, antiviral, antifungal, and antioxidant effects, the application of juglone (5-hydroxy-1,4,-naphthoquinone) is limited due to its low water solubility and allelopathic and toxic effects.
Erisen Semiha +4 more
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