Results 11 to 20 of about 44,745 (266)
Preparation of PLGA Nanoparticles by Milling Spongelike PLGA Microspheres
Pharmaceutics, 2022 Currently, emulsification-templated nanoencapsulation techniques (e.g., nanoprecipitation) have been most frequently used to prepare poly-d,l-lactide-co-glycolide (PLGA) nanoparticles. This study aimed to explore a new top-down process to produce PLGA nanoparticles.
Jimin Lee, Hongkee Sah
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Study of Thermal Degradation of PLGA, PLGA Nanospheres and PLGA/Maghemite Superparamagnetic Nanospheres [PDF]
Materials Research, 2015 Poly(glycolide-co-lactide) (PLGA) nanospheres containing magnetic materials have been extensively studied because of its biomedical applications. Therefore, it is very important to know thermal properties of these materials in addition to other physical properties. Thermal degradation activation energy (Eα) of PLGA nanospheres with maghemite entrapment
Silva, Marcela Fernandes +4 more
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PLGA Particles in Immunotherapy
Pharmaceutics, 2023 Poly(lactic-co-glycolic acid) (PLGA) particles are a widely used and extensively studied drug delivery system. The favorable properties of PLGA such as good bioavailability, controlled release, and an excellent safety profile due to the biodegradable polymer backbone qualified PLGA particles for approval by the authorities for the application as a drug
Dennis Horvath, Michael Basler
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Influence of PLGA and PLGA-PEG on the dissolution profile of oxaliplatin [PDF]
Polímeros, 2016 Abstract Oxaliplatin was inserted into polymeric matrices aiming to study the interaction of this drug with these polymers and its capability to diffuse to the environment. Tested polymers were: (1) polyethylene glycol (PEG), (2) poly(lactic-co-glycolic acid) (PLGA), and (3) a copolymer of them (PLGA-PEG).
Pereira, Emiliane Daher +8 more
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CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis [PDF]
BioImpacts, 2022 Introduction: The limited efficacy of BCG (bacillus Calmette–Guérin) urgently requires new effective vaccination approaches for the control of tuberculosis. Poly lactic-co-glycolic acid (PLGA) is a prevalent drug delivery system.
Zhengmin Liang +8 more
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Branched PLGA derivatives with tailored drug delivery properties
Acta Pharmaceutica, 2020 Despite several shortcomings such as extreme hydrophobicity, low drug capacity, characteristic triphasic drug release pattern with a high burst effect, poly(lactic-co-glycolic acid derivatives are widely used in drug delivery.
Snejdrova Eva +4 more
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Bioengineering, 2019 Thermoresponsive hydrogels showing biocompatibility and degradability have been under intense investigation for biomedical applications, especially hydrogels composed of hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(lactic acid-co-glycolic
Tomoki Maeda
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Drug Design, Development and Therapy, 2021 Yang Sun, Di Long Department of Orthopaedics, Affiliated Central Hospital of Shenyang Medical College, Shenyang, People’s Republic of ChinaCorrespondence: Yang Sun Email sunyang797979@163.comBackground: The present work is an effort to develop a ...
Sun Y, Long D
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Vaccines, 2019 Formulation of inhalable delivery systems containing tuberculosis (TB) antigens to target the site of infection (lungs) have been considered for the development of subunit vaccines. Inert delivery systems such as poly (lactic-co-glycolic acid) (PLGA) are
Carla B. Roces +4 more
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Cytotoxic and mutagenic potential of juglone: a comparison of free and nano-encapsulated form
Arhiv za Higijenu Rada i Toksikologiju, 2020 Despite its evidenced beneficial herbicidal, antibacterial, antiviral, antifungal, and antioxidant effects, the application of juglone (5-hydroxy-1,4,-naphthoquinone) is limited due to its low water solubility and allelopathic and toxic effects.
Erisen Semiha +4 more
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