Results 31 to 40 of about 42,358 (170)
Indonesian Journal of Chemistry, 2022 The biodegradable polymer poly(lactic-co-glycolic acid) (PLGA) is a biomaterial with great potential as a drug delivery carrier and a tissue engineering scaffold.
Diah Lestari +2 more
doaj +1 more source
Protein-loaded PLGA–PEG–PLGA microspheres: A tool for cell therapy
European Journal of Pharmaceutical Sciences, 2012 A promising strategy to repair injured organs is possible by delivering a growth factor via poly-(d,l lactide-co-glycolide) (PLGA) microspheres; the latter are coated with adhesion molecules that serve as a support for cell delivery. At present, PLGA is not the optimal choice of polymer because of poor or incomplete protein release.
Van-Thanh, Tran +6 more
openaire +2 more sources
Surface modification of PLGA microspheres [PDF]
Journal of Biomedical Materials Research Part A, 2003 AbstractMicrospheres made of poly(lactic‐co‐glycolic acid) (PLGA) are biocompatible and biodegradable, rendering them a promising tool in the context of drug delivery. However, nonspecific adsorption of plasma proteins on PLGA micro‐ and nanospheres is a main limitation of drug targeting.
Müller M +7 more
openaire +3 more sources
Synergistic co-administration of doxorubicin and berberine by PLGA/PVA hybrid polymeric Nanoformulation for breast cancer treatment [PDF]
Nanomedicine JournalObjective(s): The clinical application of doxorubicin (DOX), a potent anticancer agent, is restricted by its serious side-effects and multidrug resistance.
Masoumeh Rahmani +4 more
doaj +1 more source
Medical Journal of BabylonBackground: Many people all around the world suffer from tooth decay, a chronic infectious disease that can lead to tooth loss. Streptococcus mutans and Candida albicans are typical microorganisms involved in the caries process.
Ghada Abdul Salam Ibrahim +2 more
doaj +1 more source
Drug Delivery, 2019 Cisplatin is the most commonly used antitumor drug in the chemotherapy of a variety of malignancies. However, the severe side effects and drug resistance limit its clinical application.
Li Gao +9 more
doaj +1 more source
Biomedical Photonics, 2019 The article describes the process of developing a technology for producing nanoparticles based on a copolymer of lactic and glycolic acids (PLGA) containing dipropoxybacteriopurpurinimide (DPBPI) for photodynamic therapy of malignant tumors of various ...
M. D. Sapelnikov +7 more
doaj +1 more source
Porous polymer coatings on metal microneedles for enhanced drug delivery [PDF]
Royal Society Open Science, 2018 We present a simple method to coat microneedles (MNs) uniformly with a porous polymer (PLGA) that can deliver drugs at high rates. Stainless steel (SS) MNs of high mechanical strength were coated with a thin porous polymer layer to enhance their delivery
Asad Ullah, Chul Min Kim, Gyu Man Kim
doaj +1 more source
Sustained release of sodium deoxycholate from PLGA–PEG–PLGA thermosensitive polymer [PDF]
Artificial Cells, Nanomedicine, and Biotechnology, 2018 Delivery of the drugs to the target tissue and reducing their side effects on surrounding tissues is still a significant challenge for pharmaceutical scientists. The aim of this study was to investigate the suitability of PLGA–PEG–PLGA triblock copolymer as a matrix material for a sustained-release system of sodium deoxycholate (NaDC).
Parisa, Nasrollahi +5 more
openaire +2 more sources
Formulation of stabilizer-free, nontoxic PLGA and elastin-PLGA nanoparticle delivery systems
International Journal of Pharmaceutics, 2021 Biocompatible nanoparticles composed of poly(lactic-co-glycolic acid) (PLGA) are used as drug and vaccine delivery systems because of their tunability in size and sustained release of cargo molecules. While the use of toxic stabilizers such as polyvinyl alcohol (PVA) limit the utility of PLGA, stabilizer-free PLGA nanoparticles are rarely used because ...
Zachary R, Stromberg +11 more
openaire +2 more sources