Results 21 to 30 of about 42,358 (170)
British Journal of Pharmacy, 2019 The main objective of this work was to formulate novel amphiphilic PLGA nanoparticles with improved physicochemical properties for the delivery of the novel peptide (CK-10) to be used for targeting of the cancerous/tumour tissue.
Ahmed M Faheem +3 more
doaj +1 more source
PLGA – THE SMART POLYMER FOR DRUG DELIVERY
Фармация и фармакология (Пятигорск), 2021 Polymers have become an integral part of novel drug delivery system. One such successful biodegradable polymer is poly lactic-co-glycolic acid (PLGA) which consists of polyesters of lactic acid and glycolic acid.
N. Surya, S. Bhattacharyya
doaj +1 more source
British Journal of Pharmacy, 2019 Ran is a small RAS-related GTPase and is overexpressed in breast carcinoma to induce malignant transformation and metastatic growth. A novel series of antiRan-GTPase peptide (CK-10), which inhibits Ran hydrolysis and activation, have suboptimal activity ...
Ahmed M Faheem +3 more
doaj +1 more source
Science and Technology of Advanced Materials, 2021 Multifunctional nanocarriers have attracted considerable interest in improving cancer treatment outcomes. Poly(lactide-co-glycolide) (PLGA) nanospheres encapsulating copper oxide nanoparticles (CuO-NPs) are characterized by antitumor activity and exhibit
Inbal Maor +8 more
doaj +1 more source
Nanopartículas no tratamento da doença de alzheimer
Millenium, 2022 Introdução: A Doença de Alzheimer é uma patologia neurodegenerativa primária, de etiologia desconhecida e influenciada por vários fatores com aspetos neuropatológicos e neuroquímicos característicos.
Luísa Cruz Lopes +7 more
doaj +1 more source
A nanoparticle loaded nasal sol-gel system of midazolam hydrochloride for the management of intermittent seizures [PDF]
Nanomedicine JournalObjective(s): Midazolam hydrochloride is a short-acting hypnotic sedative with anticonvulsant properties. Considering the poor bioavailability, rapid elimination, and inconvenience of administering oral medication in epileptic conditions, this study ...
Venkatesh Srinivasan +3 more
doaj +1 more source
British Journal of Pharmacy, 2022 The aim of this project is to produce antibiotic-loaded poly (lactic-co-glycolic acid) (PLGA) polymer films by airbrush onto orthopaedic implants to address prosthetic joint infections (PJIs).
Tiancheng Luo +2 more
doaj +1 more source
Thermosensitive PLGA–PEG–PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy
Pharmaceutics, 2022 Allergen-specific immunotherapy (AIT) is the only currently available curative treatment option for allergic diseases. AIT often includes depot-forming and immunostimulatory adjuvants, to prolong allergen presentation and to improve therapeutic efficacy.
Sonja Heine +12 more
openaire +4 more sources
Drug Delivery, 2017 The natural product berberine (BBR), present in various plants, arouses great interests because of its numerous pharmacological effects. However, the further development and application of BBR had been hampered by its poor oral bioavailability.
Fei Yu +9 more
doaj +1 more source
Drug Delivery, 2020 The aim of this study is to prepare and evaluate the antibacterial and antibiofilm activity of ciprofloxacin (CIP) loaded PLGA nanoparticles (F2) and CIP-PLGA nanoparticles coated with chitosan (F3) versus ciprofloxacin solution (Fl) as a control on ...
Mona G. Arafa +2 more
doaj +1 more source