Results 21 to 30 of about 44,745 (266)
British Journal of Pharmacy, 2019 The main objective of this work was to formulate novel amphiphilic PLGA nanoparticles with improved physicochemical properties for the delivery of the novel peptide (CK-10) to be used for targeting of the cancerous/tumour tissue.
Ahmed M Faheem +3 more
doaj +1 more source
PLGA – THE SMART POLYMER FOR DRUG DELIVERY
Фармация и фармакология (Пятигорск), 2021 Polymers have become an integral part of novel drug delivery system. One such successful biodegradable polymer is poly lactic-co-glycolic acid (PLGA) which consists of polyesters of lactic acid and glycolic acid.
N. Surya, S. Bhattacharyya
doaj +1 more source
British Journal of Pharmacy, 2019 Ran is a small RAS-related GTPase and is overexpressed in breast carcinoma to induce malignant transformation and metastatic growth. A novel series of antiRan-GTPase peptide (CK-10), which inhibits Ran hydrolysis and activation, have suboptimal activity ...
Ahmed M Faheem +3 more
doaj +1 more source
Science and Technology of Advanced Materials, 2021 Multifunctional nanocarriers have attracted considerable interest in improving cancer treatment outcomes. Poly(lactide-co-glycolide) (PLGA) nanospheres encapsulating copper oxide nanoparticles (CuO-NPs) are characterized by antitumor activity and exhibit
Inbal Maor +8 more
doaj +1 more source
Nanopartículas no tratamento da doença de alzheimer
Millenium, 2022 Introdução: A Doença de Alzheimer é uma patologia neurodegenerativa primária, de etiologia desconhecida e influenciada por vários fatores com aspetos neuropatológicos e neuroquímicos característicos.
Luísa Cruz Lopes +7 more
doaj +1 more source
A nanoparticle loaded nasal sol-gel system of midazolam hydrochloride for the management of intermittent seizures [PDF]
Nanomedicine JournalObjective(s): Midazolam hydrochloride is a short-acting hypnotic sedative with anticonvulsant properties. Considering the poor bioavailability, rapid elimination, and inconvenience of administering oral medication in epileptic conditions, this study ...
Venkatesh Srinivasan +3 more
doaj +1 more source
British Journal of Pharmacy, 2022 The aim of this project is to produce antibiotic-loaded poly (lactic-co-glycolic acid) (PLGA) polymer films by airbrush onto orthopaedic implants to address prosthetic joint infections (PJIs).
Tiancheng Luo +2 more
doaj +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Protein-loaded PLGA–PEG–PLGA microspheres: A tool for cell therapy
European Journal of Pharmaceutical Sciences, 2012 A promising strategy to repair injured organs is possible by delivering a growth factor via poly-(d,l lactide-co-glycolide) (PLGA) microspheres; the latter are coated with adhesion molecules that serve as a support for cell delivery. At present, PLGA is not the optimal choice of polymer because of poor or incomplete protein release.
Van-Thanh, Tran +6 more
openaire +2 more sources
Thermosensitive PLGA–PEG–PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy
Pharmaceutics, 2022 Allergen-specific immunotherapy (AIT) is the only currently available curative treatment option for allergic diseases. AIT often includes depot-forming and immunostimulatory adjuvants, to prolong allergen presentation and to improve therapeutic efficacy.
Sonja Heine +12 more
openaire +4 more sources