Results 21 to 30 of about 90,317 (313)
Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer [PDF]
BioImpacts, 2022 Introduction: Paclitaxel (PTX) is a cornerstone in the treatment of breast cancer, the most common type of cancer in women. However, this drug has serious limitations, including lack of tissue-specificity, poor water solubility, and the development of ...
Laura Cabeza +9 more
doaj +1 more source
A perfusion culture system for assessing bone marrow stromal cell differentiation on PLGA scaffolds for bone repair [PDF]
, 2018 Biomaterials development for bone repair is currently hindered by the lack of physiologically relevant in vitro testing systems. Here we describe the novel use of a bi-directional perfusion bioreactor to support the long term culture of human bone marrow
Alini, Mauro +5 more
core +2 more sources
Drug Design, Development and Therapy, 2021 Yang Sun, Di Long Department of Orthopaedics, Affiliated Central Hospital of Shenyang Medical College, Shenyang, People’s Republic of ChinaCorrespondence: Yang Sun Email sunyang797979@163.comBackground: The present work is an effort to develop a ...
Sun Y, Long D
doaj
Encapsulation of human serum albumin in submicrometer magnetic poly(lactide-co-glycolide) particles as a model system for targeted drug delivery [PDF]
, 2013 Two types of iron oxide nanoparticles were synthesized by coprecipitation of Fe(II) and Fe(III) chlorides: water-dispersible γ-Fe2O3 and organic solvent-dispersible oleic acid-coated Fe3O4 particles.
Feczkó, Tivadar +6 more
core +1 more source
Sustained release of sodium deoxycholate from PLGA–PEG–PLGA thermosensitive polymer [PDF]
Artificial Cells, Nanomedicine, and Biotechnology, 2018 Delivery of the drugs to the target tissue and reducing their side effects on surrounding tissues is still a significant challenge for pharmaceutical scientists. The aim of this study was to investigate the suitability of PLGA–PEG–PLGA triblock copolymer as a matrix material for a sustained-release system of sodium deoxycholate (NaDC).
Parisa, Nasrollahi +5 more
openaire +2 more sources
Vaccines, 2019 Formulation of inhalable delivery systems containing tuberculosis (TB) antigens to target the site of infection (lungs) have been considered for the development of subunit vaccines. Inert delivery systems such as poly (lactic-co-glycolic acid) (PLGA) are
Carla B. Roces +4 more
doaj +1 more source
Cytotoxic and mutagenic potential of juglone: a comparison of free and nano-encapsulated form
Arhiv za Higijenu Rada i Toksikologiju, 2020 Despite its evidenced beneficial herbicidal, antibacterial, antiviral, antifungal, and antioxidant effects, the application of juglone (5-hydroxy-1,4,-naphthoquinone) is limited due to its low water solubility and allelopathic and toxic effects.
Erisen Semiha +4 more
doaj +1 more source
Immunization against Pseudomonas aeruginosa using Alg-PLGA nano-vaccine [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Pseudomonas aeruginosa is the bacterium that causes of pulmonary infection among chronically hospitalized patients. Alginate is a common surface antigen of P.
Saeid Azimi, Leila Safari Zanjani
doaj +1 more source
Influence of electrostatic interactions in electrophoretic membrane contactors [PDF]
, 2002 In electrophoretic separators, a porous membrane is used to put into contact two flowing liquids between which an electrically driven mass transfer takes place. As far as charged solutes are concerned, the mass transfer can be affected by electrostatic
Galier, Sylvain +1 more
core +2 more sources
British Journal of Pharmacy, 2019 The main objective of this work was to formulate novel amphiphilic PLGA nanoparticles with improved physicochemical properties for the delivery of the novel peptide (CK-10) to be used for targeting of the cancerous/tumour tissue.
Ahmed M Faheem +3 more
doaj +1 more source