Results 41 to 50 of about 90,317 (313)

Multi-layer PLGA-pullulan-PLGA electrospun nanofibers for probiotic delivery

Food Hydrocolloids, 2022
Abstract Encapsulation of bacteria into a polymer matrix can potentially enhance the delivery of probiotics. In this study, we present a multilayer electrospun construct to facilitate enhanced delivery of probiotics, where the internal layer is loaded with bacterial cells and the external layers sandwich the internal layer for increased protection ...
Fatemeh Ajalloueian, Priscila R. Guerra, Martin Iain Bahl, Anders Meyer Torp, En Te Hwu, Tine Rask Licht, Anja Boisen   +6 more
openaire   +2 more sources

Treating Macrophages with Anti-inflammatory Nanoparticles as a Strategy to Improve Muscle Repair [PDF]

, 2019
The macrophage is an immune cell that is involved in host defense. More recent research, however, has revealed that they also play a central role in mediating the skeletal muscle regenerative process.
Yan, Derek
core   +1 more source

Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]

, 2017
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura, Chicca, Milvia, DANTI, SERENA, Franceschini, Valeria, Martini, Alessandro, Simoni, Edi, Valente, Filippo   +6 more
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The Anti-Tumor and Immunomodulatory Effects of PLGA-Based Docetaxel Nanoparticles in Lung Cancer: The Potential Involvement of Necroptotic Cell Death through Reactive Oxygen Species and Calcium Build-Up

Vaccines, 2022
Taxanes, microtubule stabilizing agents, are extensively used in the treatment of non-small cell lung cancer (NSCLC). However, their clinical effectiveness remains restricted owing to significant adverse effects and drug resistance.
Parul Gupta, Arpita Singh, Ajay Kumar Verma, Surya Kant, Anuj Kumar Pandey, Puneet Khare, Ved Prakash   +6 more
doaj   +1 more source

Self-consistent field predictions for quenched spherical biocompatible triblock copolymer micelles

, 2013
We have used the Scheutjens-Fleer self-consistent field (SF-SCF) method to predict the self-assembly of triblock copolymers with a solvophilic middle block and sufficiently long solvophobic outer blocks.
Lebouille, Jérôme G. J. L., Leermakers, Frans A. M., Stuart, Martien A. Cohen, Tuinier, Remco, Vleugels, Leo F. W.   +4 more
core   +2 more sources

Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex. [PDF]

, 2016
Bioresorbable silicon electronics technology offers unprecedented opportunities to deploy advanced implantable monitoring systems that eliminate risks, cost and discomfort associated with surgical extraction. Applications include postoperative monitoring
Bink, Hank, Cheng, Huanyu, Chiang, Ken, Dichter, Marc A, Fang, Hui, Huang, Younggang, Hwang, Suk-Won, Jensen, Frances E, Juul, Halvor, Kang, Seung-Kyun, Kim, Bong Hoon, Kim, Jae-Hwan, Kim, Nam Heon, Kuzum, Duygu, Lee, Hee Nam, Lee, Jung Yup, Litt, Brian, Lucas, Timothy H, Richardson, Andrew G, Rogers, John A, Seo, Kyung Jin, Talos, Delia, Thomson, Marissa, Trumpis, Michael, Viventi, Jonathan, Won, Sang Min, Yu, Ki Jun   +26 more
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Surface modification of PLGA microspheres [PDF]

Journal of Biomedical Materials Research Part A, 2003
AbstractMicrospheres made of poly(lactic‐co‐glycolic acid) (PLGA) are biocompatible and biodegradable, rendering them a promising tool in the context of drug delivery. However, nonspecific adsorption of plasma proteins on PLGA micro‐ and nanospheres is a main limitation of drug targeting.
M, Müller, J, Vörös, G, Csúcs, E, Walter, G, Danuser, H P, Merkle, N D, Spencer, M, Textor   +7 more
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A nanoparticle loaded nasal sol-gel system of midazolam hydrochloride for the management of intermittent seizures [PDF]

Nanomedicine Journal
Objective(s): Midazolam hydrochloride is a short-acting hypnotic sedative with anticonvulsant properties. Considering the poor bioavailability, rapid elimination, and inconvenience of administering oral medication in epileptic conditions, this study ...
Venkatesh Srinivasan, Preethi Sudheer, Keserla Bhavani, Arumugam Muthu Kumar   +3 more
doaj   +1 more source

Design and testing of hydrophobic core/hydrophilic shell nano/micro particles for drug-eluting stent coating [PDF]

, 2018
In this study, we designed a novel drug-eluting coating for vascular implants consisting of a core coating of the anti-proliferative drug docetaxel (DTX) and a shell coating of the platelet glycoprotein IIb/IIIa receptor monoclonal antibody SZ-21.
A Arsiwala, A Bierhalz, A Tan, AW Heldman, B Almería, B O’brien, B O’Brien, C Stettler, CJ Pan, CJ Sweeney, CL Song, D Sun, DM Saylor, E Boersma, E Camenzind, ES Park, ES Thian, F Danhier, GY An, H Zhang, HG Wang, J Kanzer, J Riegger, J Yang, J Zhang, JB Slee, JJ Wykrzykowska, JM Lee, JV Natarajan, K Kolandaivelu, KH Bønaa, KS Lim, M Gawaz, M Zamani, M Zamani, MK Dong, MP Skinner, MT Ali, PS Douglas, PW Erruys, RH Müller, RK Aggarwal, RL Wilensky, S Freiberg, S Garg, S Hossfeld, S Jang, S Lee, S Mcginty, S Meng, S Puricel, S Yasuda, SJ Liu, T Inoue, T Nakano, TM Ko, U Baber, X Ma, X Wu, X Xi, Y Cao, YH Lee, Z Yang   +62 more
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Formulation of stabilizer-free, nontoxic PLGA and elastin-PLGA nanoparticle delivery systems

International Journal of Pharmaceutics, 2021
Biocompatible nanoparticles composed of poly(lactic-co-glycolic acid) (PLGA) are used as drug and vaccine delivery systems because of their tunability in size and sustained release of cargo molecules. While the use of toxic stabilizers such as polyvinyl alcohol (PVA) limit the utility of PLGA, stabilizer-free PLGA nanoparticles are rarely used because ...
Zachary R, Stromberg, M, Lisa Phipps, Harsha D, Magurudeniya, Christine A, Pedersen, Trideep, Rajale, Chris J, Sheehan, Samantha J, Courtney, Steven B, Bradfute, Peter, Hraber, Matthew N, Rush, Jessica Z, Kubicek-Sutherland, Jennifer S, Martinez   +11 more
openaire   +2 more sources