Results 41 to 50 of about 44,745 (266)

The Antimicrobial Effects of Poly(Lactic-Co-Glycolic Acid)/Xylitol Nanoparticles on Microorganisms Causing Dental Caries (In Vitro Study)

open access: yesMedical Journal of Babylon
Background: Many people all around the world suffer from tooth decay, a chronic infectious disease that can lead to tooth loss. Streptococcus mutans and Candida albicans are typical microorganisms involved in the caries process.
Ghada Abdul Salam Ibrahim   +2 more
doaj   +1 more source

Soft and Transient Bioelectronics Enabled by Polymer‐Free Ti3C2Tx MXene Hydrogels

open access: yesAdvanced Materials, EarlyView.
We present Ti3C2Tx MXene hydrogel (MXgel) bioelectronics, a soft, flexible, and fully transient platform for high‐fidelity neural recording and stimulation. MXgel bioelectronics exhibit exceptional electrical conductivities, low electrochemical impedances, and high charge injection capacities.
Raghav Garg   +15 more
wiley   +1 more source

The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice

open access: yesDrug Delivery, 2019
Cisplatin is the most commonly used antitumor drug in the chemotherapy of a variety of malignancies. However, the severe side effects and drug resistance limit its clinical application.
Li Gao   +9 more
doaj   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

open access: yesAdvanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani   +2 more
wiley   +1 more source

Development of the technology for obtaining PLGA and dipropoxybateriopurpurinimide-based nanoparticles. Evaluation of physicochemical and biological properties of the obtained delivery system

open access: yesBiomedical Photonics, 2019
The article describes the process of developing a technology for producing nanoparticles based on a copolymer of lactic and glycolic acids (PLGA) containing dipropoxybacteriopurpurinimide (DPBPI) for photodynamic therapy of malignant tumors of various ...
M. D. Sapelnikov   +7 more
doaj   +1 more source

Formulation of stabilizer-free, nontoxic PLGA and elastin-PLGA nanoparticle delivery systems

open access: yesInternational Journal of Pharmaceutics, 2021
Biocompatible nanoparticles composed of poly(lactic-co-glycolic acid) (PLGA) are used as drug and vaccine delivery systems because of their tunability in size and sustained release of cargo molecules. While the use of toxic stabilizers such as polyvinyl alcohol (PVA) limit the utility of PLGA, stabilizer-free PLGA nanoparticles are rarely used because ...
Zachary R, Stromberg   +11 more
openaire   +2 more sources

Recent Advances in Transparent Microelectrode Device Architecture and Fabrication Strategies for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan   +6 more
wiley   +1 more source

Porous polymer coatings on metal microneedles for enhanced drug delivery [PDF]

open access: yesRoyal Society Open Science, 2018
We present a simple method to coat microneedles (MNs) uniformly with a porous polymer (PLGA) that can deliver drugs at high rates. Stainless steel (SS) MNs of high mechanical strength were coated with a thin porous polymer layer to enhance their delivery
Asad Ullah, Chul Min Kim, Gyu Man Kim
doaj   +1 more source

Injectable In-Situ Forming Depot Based on PLGA and PLGA-PEG-PLGA for Sustained-Release of Risperidone: In Vitro Evaluation and Pharmacokinetics in Rabbits

open access: yesPharmaceutics, 2023
In the current research, novel drug delivery systems based on in situ forming gel (ISFG) (PLGA-PEG-PLGA) and in situ forming implant (ISFI) (PLGA) were developed for one-month risperidone delivery. In vitro release evaluation, pharmacokinetics, and histopathology studies of ISFI, ISFG, and Risperdal CONSTA® were compared in rabbits.
Seyedeh Nesa Rezaeian Shiadeh   +6 more
openaire   +3 more sources

Moisture‐Adaptive Triboelectric Materials and Platforms: Design Strategies, Performance Enhancement, and Applications in Energy Harvesting and Wearable Electronics

open access: yesAdvanced Materials Technologies, EarlyView.
This review summarizes moisture‐adaptive strategies that enable triboelectric nanogenerators (TENGs) to operate across diverse moisture conditions. It examines moisture‐management methods, including exclusion, directional transport, removal, and utilization, with charge‐regulation approaches based on interfacial, dielectric, and structural engineering.
Junzhe Gan   +4 more
wiley   +1 more source

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