Results 51 to 60 of about 42,358 (170)
Microfluidics-Assisted Size Tuning and Biological Evaluation of PLGA Particles
Pharmaceutics, 2019 Polymeric particles made up of biodegradable and biocompatible polymers such as poly(lactic-co-glycolic acid) (PLGA) are promising tools for several biomedical applications including drug delivery.
Maria Camilla Operti +5 more
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PLGA‐PEG‐PLGA hydrogels induce cytotoxicity in conventional in vitro assays
Cell Biochemistry and FunctionSignificance statementWe identified that PLGA‐PEG‐PLGA hydrogels, which have been used in human clinical trials and possess a demonstrable safety profile, induced significant cytotoxicity in conventional in vitro assays. This major contradiction may lead to inconsistent and misleading toxicology due to the limited biological representation of these ...
Stewart, CL +4 more
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Comparative analysis of PLGA ocuserts of brimonidine tartrate prepared with different methods
European Pharmaceutical JournalThe eye is a highly sensitive organ with multiple physiological barriers that limit drug bioavailability and reduce patient compliance. Research studies are still going on to discover a novel drug delivery system for ocular delivery. The current research
Paramjot +4 more
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Nano Biomedicine and Engineering, 2011 The purpose of this work was to obtain an optimized Human Serum Albumin (HSA)-loaded poly(lactic-co-glycolic acid)(PLGA) nanoparticles (NPs). A rotatable central composite design (RCCD) was applied to evaluate the joint influence of three formulation ...
Hua Song +6 more
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International Journal of Nanomedicine, 2021 Wenfeng Lin,1,* Chaoming Li,1,2,* Naijin Xu,1,3 Masami Watanabe,1,4 Ruizhi Xue,1 Abai Xu,2 Motoo Araki,1 Ruifen Sun,5 Chunxiao Liu,2 Yasutomo Nasu,1 Peng Huang1,2,6 1Department of Urology, Okayama University Graduate School of Medicine, Dentistry and ...
Lin W +10 more
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The effect of PLGA-PEG-PLGA modification on the sol-gel transition and degradation properties
Express Polymer Letters, 2016 This paper deals with the influence of an incubation medium pH on the hydrolytic degradation of a novel thermosensitive biodegradable triblock copolymer based on hydrophilic poly(ethylene glycol) and hydrophobic copolymer poly(lactic acid-co-glycolic acid) (PLGA-PEG-PLGA), consequently modified at α,ω-ends with itaconic acid (ITA) resulting in α,ω ...
Oborná, Jana +4 more
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Animals, 2019 Pulmonary fibrosis is considered one of the most chronic interstitial illnesses which are not easily treated. thymoquinone’s (TQ) benefits are still partly problematic due to poor water solubility; therefore, it was loaded onto PLGA-PVA carriers ...
Sultan A. M. Saghir +8 more
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Cogent Medicine, 2016 Effective and sustained release formulations of antimetabolite 5-Flurouracil (5Fu) for ocular fibrosis are highly desirable for success of glaucoma filtration surgery (GFS).
Meghali Bora +4 more
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Drug Design, Development and Therapy, 2021 Rana M Gebreel,1 Noha A Edris,2 Hala M Elmofty,2 Mina I Tadros,3,4 Mohamed A El-Nabarawi,3 Doaa H Hassan1 1Department of Pharmaceutics, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt ...
Gebreel RM +5 more
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International Journal of Nanomedicine, 2020 Mona G Arafa,1,2 Germeen NS Girgis,3 Marwa S El-Dahan3 1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, The British University in Egypt (BUE), El-Sherouk City, Cairo, 11837, Egypt; 2Chemotherapeutic Unit, Mansoura ...
Arafa MG, Girgis GNS, El-Dahan MS
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