Results 271 to 280 of about 37,805 (321)

Tracking the Evolution of Cutaneous Melanoma by Multiparameter Flow Sorting and Genomic Profiling. [PDF]

Int J Mol Sci
Roma L, Lorber T, Rau S, Barrett MT, Ercan C, Panebianco F, Piscuoglio S, Glatz K, Bubendorf L, Ruiz C.   +9 more
europepmc   +1 more source

Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing

The Journal of Pathology, Volume 267, Issue 3, Page 347-365, November 2025.
Abstract The most common cause of death in pediatric cancer patients is a treatment‐resistant tumor, compounded by metastatic spread, making surgery, radiation therapy, and chemotherapy unfeasible as curative treatment options. However, the mechanisms behind metastatic spread in pediatric tumors remain largely unexplored. We conducted whole‐genome copy
Natalie Andersson, Michele Ferro, Caroline Jansson, Subhayan Chattopadhyay, Jenny Karlsson, David Gisselsson   +5 more
wiley   +1 more source

Neuroblastoma in Infants: Long‐Term Survival From INES Protocols A SIOPEN Study

Pediatric Blood &Cancer, Volume 72, Issue 11, November 2025.
ABSTRACT Objectives Neuroblastoma is the most common extracranial solid tumor in infants, with a possibility of spontaneous regression even in disseminated disease. Despite an overall good prognosis, relapse can worsen the outcome for some patients. A long‐term analysis is crucial to identify subgroups of patients with poorer prognosis, assessing the ...
Julie Savagner, Caroline Munzer, Gudrun Schleiermacher, Alberto Garaventa, Riccardo Haupt, Stefania Sorrentino, Katia Mazzocco, Andrea Di Cataldo, Adela Canete, Vanessa Segura, Desiree Ramal, Kate Wheeler, Ruth Ladenstein, Ana Forjaz de Lacerda, Benedicte Brichard, Maja Beck‐Popovic, Dominique Valteau‐Couanet, Claudia Pasqualini, Carole Coze, Benoit Dumont, Anne Sophie Defachelles, Marion Gambart   +21 more
wiley   +1 more source

Hepatic Nuclear Ploidy Distribution of Dietary-Restricted Mice

, 1993
Ming Lü, William G. Hinson, Dansha He, Angelo Turturro, Ronald W. Hart   +4 more
openalex   +1 more source

Chloroplast genome diversity and phylogenetic insights of Saccharum spontaneum across Southeast Asia

PLANTS, PEOPLE, PLANET, Volume 7, Issue 6, Page 1834-1844, November 2025.
Climate change and threats to global food security have increased the urgency of conserving genetic resources in key crops like sugarcane. In this study, we analyzed the chloroplast genomes of wild sugarcane to assess their genetic diversity and population structure. We found a high level of diversity, regardless of geographic location, and patterns of
Sicheng Li, Zhen Wang, Chaohua Xu, Lijun Zhang, Baoqing Zhang, Yuxin Huang, Xin Lu, Weixing Duan, Xiping Yang   +8 more
wiley   +1 more source

Whole-genome duplication reshapes adaptation: autotetraploid Arabidopsis arenosa leverages its high genetic variation to compensate for selection constraints.

Celestini S, Lipanova V, Vlcek J, Kolar F.   +3 more
europepmc   +1 more source

Fragility of ER homeostatic regulation underlies haploid instability in human somatic cells. [PDF]

J Biol Chem
Ishida-Ishihara S, Yaguchi K, Miura S, Nomura R, Wang Q, Yoshizawa K, Sato K, Yang G, Veszelyi K, Banhegyi G, Margittai E, Uehara R.   +11 more
europepmc   +1 more source

CUSCO: A Tool for Curating Single‐Copy Orthologs and Extracting Marker Genes for Phylogenetic Tree Construction With Extra Samples

Ecological Research, Volume 40, Issue 6, November 2025.
We developed the CUSCO pipeline. It enables rapid construction of a phylogenetic tree using whole genome sequences and identifies useful marker genes for additional samples. It can handle polyploid genomes. ABSTRACT Single‐copy orthologs are often used to reconstruct phylogenetic trees of life. A set of single‐copy orthologs can be prepared by building
Takashi Seiko, Koki Nagasawa, Ken Naito
wiley   +1 more source

Species integrity and ploidy stability despite extensive gene flow via introgressive hybridization: the case of Betula species in Iceland. [PDF]

BMC Plant Biol
Leduc GB, Thórsson ÆT, Anamthawat-Jónsson K.   +2 more
europepmc   +1 more source

Enrichment of Helminth Mitochondrial Genomes From Faecal Samples Using Hybridisation Capture

Molecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT New approaches are urgently needed to enrich rare or low‐abundant DNA in complex samples. Soil‐transmitted helminths (STHs) inhabit heterogeneous environments, including the gastrointestinal tract of their host as adults and are excreted as eggs and larvae in faeces, complicating our understanding of their biology and the use of genetic tools ...
Marina Papaiakovou, Andrea Waeschenbach, Roy M. Anderson, Piet Cools, Zeleke Mekonnen, D. Timothy J. Littlewood, Cinzia Cantacessi, Stephen R. Doyle   +7 more
wiley   +1 more source