Results 91 to 100 of about 90,784 (353)

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells [PDF]

, 2015
Oncogenic signaling in melanocytes results in oncogene-induced senescence (OIS), a stable cell-cycle arrest frequently characterized by a bi- or multinuclear phenotype that is considered as a barrier to cancer progression.
Bröcker, E.-B., Haferkamp, S., Hufnagel, A.L., Kneitz, S., Leikam, C., Meierjohann, S., Murphy, D.J., Mühling, B., Nanda, I., Otto, C., Schartl, M., Schmid, M., Wagner, T.U.   +12 more
core   +2 more sources

tidypopgen: Tidy population genetics in R

Methods in Ecology and Evolution, EarlyView.
Abstract As genome‐wide data have become increasingly available, software libraries for their analysis have proliferated. While new tools for downstream analyses are constantly emerging, existing workflows are hindered by inefficiencies. Switching between coding languages and object types in the early stages of pipelines wastes researchers' time ...
Evelyn J. Carter, Eirlys E. Tysall, Jason A. Hodgson, Andrea Manica   +3 more
wiley   +1 more source

Aneuploidy among androgenic progeny of hexaploid triticale (XTriticosecale Wittmack). [PDF]

, 2010
Doubled haploids are an established tool in plant breeding and research. Of several methods for their production, androgenesis is technically simple and can efficiently produce substantial numbers of lines.
Lukaszewski, Adam J, Oleszczuk, Sylwia, Rabiza-Swider, Julita, Zimny, Janusz   +3 more
core   +3 more sources

Dynamics of circulating tumour DNA in relapsed/refractory diffuse large B‐cell lymphoma patients

British Journal of Haematology, EarlyView.
Summary The response to salvage chemotherapy in relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) is poor, and data on circulating tumour deoxyribonucleic acid (ctDNA) in this setting are limited. We evaluated ctDNA dynamics in 29 patients with relapsed or refractory DLBCL who received platinum‐based salvage chemotherapy at the University
Yujie Zhong, Johanna Bult, Nick Veltmaat, Filipe Montes de Jesus, Laurens Sillje, Joost Kluiver, Anke van den Berg, Wouter Plattel, Arjan Diepstra, Marcel Nijland   +9 more
wiley   +1 more source

Aneuploidy and proteotoxic stress in cancer [PDF]

, 2015
Although nearly ubiquitous in cancer, aneuploidy exerts detrimental effects on human cells. We recently demonstrated that aneuploid human cells exhibit impaired heat shock factor protein 1 (HSF1) and HSP90 function, suggesting a functional link between ...
Donnelly, N., Storchova, Z.
core   +2 more sources

A century of theories of balancing selection

Biological Reviews, EarlyView.
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka, Martyna K. Zwoinska, Debora Goedert, Hanna Kokko, Xiang‐Yi Li Richter, Iain R. Moodie, Sofie Nilén, Colin Olito, Erik I. Svensson, Peter Czuppon, Tim Connallon   +10 more
wiley   +1 more source

Plant Domestication Affects the Oviposition Behavior and Performance of Ganaspis kimorum, a Parasitoid of Drosophila suzukii

Entomologia Experimentalis et Applicata, EarlyView.
In this study, we investigated the effects of blueberry domestication on the oviposition behavior and performance of Ganaspis kimorum, a parasitoid of Drosophila suzukii. Domestication of blueberries reduced the oviposition‐searching behavior of the parasitoid but enhanced parasitoid performance, including offspring performance. Additionally, blueberry
Yahel Ben‐Zvi, Cesar Rodriguez‐Saona
wiley   +1 more source

Metagenomics for Bacteriology [PDF]

, 2015
The study of bacteria, or bacteriology, has gone through transformative waves since its inception in the 1600s. It all started by the visualization of bacteria using light microscopy by Antonie van Leeuwenhoek, when he first described “animalcules ...
del Castillo, Erika, Izard, Jacques
core   +1 more source

Molecular footprints of the Holocene retreat of dwarf birch in Britain [PDF]

, 2014
© 2014 The Authors. Molecular Ecology Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original ...
Atkinson MD, Avise JC, Brown IR, Brown IR, Furrer R, Hammer Ø, Huntley B, Linnaeus C, Mellersh C, Phillips SJ, Pritchard JK, R Core Team, Rich TCG, Stace CA, Stebbins GL   +14 more
core   +1 more source