Results 51 to 60 of about 75,541 (203)

Stem-Like Adaptive Aneuploidy and Cancer Quasispecies [PDF]

, 2013
We analyze and reinterpret experimental evidence from the literature to argue for an ability of tumor cells to self-regulate their aneuploidy rate. We conjecture that this ability is mediated by a diversification factor that exploits molecular mechanisms
Napoletani, Domenico, Signore, Michele, Struppa, Daniele C.   +2 more
core   +4 more sources

CATECHOLAMINE SECRETION AND PLOIDY IN PHAEOCHROMOCYTOMA

International Journal of Clinical Practice, 2000
SUMMARYThe aim was to evaluate 24 hr urine catecholamine, HMMA and HVA excretion in relation to ploidy in phaeochromocytoma. Data from five diploid and nine tetraploid tumours showed a significant reduction in urine noradrenaline (p=0.02) and HMMA (p=0.03) in diploid tumours but no difference in adrenaline, dopamine and HVA excretion using the Mann ...
W P, Tormey, R J, Fitzgerald, G, Thomas, E W, Kay, M B, Leader   +4 more
openaire   +2 more sources

Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal, Melanie Coughlan, Andrée Nunnikhoven, Reena Corbane, Cathy Cummings‐Lorbetskie, Andrea Rowan‐Carroll, Tanvi Sharma, Andrew Williams, Jessie R. Lavoie, Andrew Stalker, Asish Mohapatra, Matthew J. Meier   +11 more
wiley   +1 more source

De Novo Whole Genome Assemblies of Unusual Case‐Making Caddisflies (Trichoptera) Highlight Genomic Convergence in the Composition of the Major Silk Gene (h‐fibroin)

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
The major silk gene, h‐fibroin, was annotated in high‐quality genomes of two unusual case‐making Trichoptera. H‐Fibroin of Limnocentropus insolitus shows a similar amino acid composition to other case‐making species, while the amino acid composition of h‐fibroin of Phryganopsyche brunnea resembles that of retreat‐making species.
Xiling Deng, Steffen U. Pauls, Ryoichi B. Kuranishi, Paul B. Frandsen, Jacqueline Heckenhauer   +4 more
wiley   +1 more source

A rewiring model of intratumoral interaction networks. [PDF]

, 2019
Intratumoral heterogeneity (ITH) has been regarded as a key cause of the failure and resistance of cancer therapy, but how it behaves and functions remains unclear.
Alizadeh, Badano, Bedard, Castro-Giner, Cleary, Couzin-Frankel, Easton, Enriquez-Navas, Fachal, Garcia-Closas, Gillies, Gosik, Greaves, Jørgensen, Kallioniemi, Komarova, Korolev, Lesseur, Li, Ling, McGranahan, Merlo, Nowak, Qazi, Saadatpour, Smith, Stadler, Tabassum, Vittecoq, Vogelstein, von Loga, von Neumann, Waclaw, Watson, Welch, Zhu   +35 more
core   +2 more sources

Variance of ploidy in Candida albicans [PDF]

Journal of Bacteriology, 1982
Determination of ploidy was performed on isolates of Candida albicans from clinical sources by measuring nuclear DNA content with fluorescent microscope photometry. By this criterion and UV irradiation survival experiments, haploid, diploid, and tetraploid strains were identified in this organism.
Takahito Suzuki, K Tanaka, S Nishibayashi, T Kuroiwa, T Kanbe   +4 more
openaire   +3 more sources

Disentangling relationships in Euphorbia agraria s.l. (Euphorbiaceae) in south‐east Europe: One or two species?

TAXON, EarlyView.
Abstract We explored the diversification of the south‐eastern and eastern European Euphorbia agraria s.l. applying molecular (amplified fragment length polymorphism [AFLP] fingerprinting and sequencing of the nuclear ribosomal internal transcribed spacer [ITS]), cytogenetic (relative genome size [RGS] estimations) and morphometric methods.
Naim Berisha, Peter Schönswetter, Božo Frajman   +2 more
wiley   +1 more source

Doubled haploid ramets via embryogenesis of haploid tissue cultures [PDF]

, 2010
Tissue culture in the oil palm business is generally concerned with the multiplication (clonal production) of dura, pisifera and tenera palms. These are all normal diploids (2n=2x=36).
Caligari, P. D. S., Dunwell, Jim M., Forster, B. P., Iswandar, H. E., Nelson, S. P. C.   +4 more
core  

Resistance to frost and tuber soft rot in near-pentaploid Solanum tuberosum - S. commersonii hybrids [PDF]

, 2007
The objectives of the present study were to evaluate the tolerance to low temperatures and tuber soft rot in sexual near-pentaploid hybrids between incongruent 2x (1EBN) Solanum commersonii (CMM) and 4x (4EBN) S. tuberosum (TBR). For freezing resistance,
AVERSANO, RICCARDO, CARPUTO, DOMENICO, CARUSO, IMMACOLATA, CASTALDI L, FRUSCIANTE, LUIGI, MONTI, LUIGI   +5 more
core   +2 more sources

Demographic history of the Malayan tapirs (Tapirus indicus) in Southeast Asia

Ecological Research, EarlyView.
Malayan tapirs in Southeast Asia can be distinguished into 3 geographical groups, based on genetic structure analysis in 11 whole genomes. The effective population size (Ne) of tapirs shows a general decreasing trend, as suggested by the pairwise sequentially Markovian coalescent analysis, with population expansion or structuring during late Early ...
Qi Luan Lim, Yu Sato, Norsyamimi Rosli, Miho Inoue‐Murayama   +3 more
wiley   +1 more source