Results 51 to 60 of about 88,719 (358)

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou   +17 more
wiley   +1 more source

Inferring Variation in Copy Number Using High Throughput Sequencing Data in R

open access: yesFrontiers in Genetics, 2018
Inference of copy number variation presents a technical challenge because variant callers typically require the copy number of a genome or genomic region to be known a priori.
Brian J. Knaus, Niklaus J. Grünwald
doaj   +1 more source

Phylogenetic relationships in Betula (Betulaceae) based on AFLP markers [PDF]

open access: yes, 2008
The genus Betula comprises various species in boreal and temperate climate zones of the Northern Hemisphere. The taxonomy of Betula is controversial and complicated by parallel evolution of morphological traits, polyploidization events, and extensive ...
Gilissen, L.J.W.J.   +4 more
core   +2 more sources

PLOIDY AND GENE EXPRESSION IN CLEMENTINE

open access: yesActa Horticulturae, 2015
Polyploidy has long been recognized as an important force in the evolution of flowering plants and often results in novel phenotypes having advantages in adaptation and major interest for agriculture. Many crops, including citrus, are bred to a higher level of ploidy in search of desirable traits.
Niñoles Rodenes, Regina   +4 more
openaire   +3 more sources

Targeting RBM10‐Repressed RORB Activity in Liquid Condensates Inhibits Lysosomal Biogenesis and Neuroblastoma Progression via Affecting NF‐κB Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies that RBM10 represses the transcriptional activity of RORB in liquid condensates, resulting in down‐regulation of NR1D1 and RIOK3 that further activates NF‐κB activity to facilitate lysosomal biogenesis and aggressive features of NB cells.
Yanhua Guo   +9 more
wiley   +1 more source

Cardiomyocyte Ploidy, Metabolic Reprogramming and Heart Repair

open access: yesCells, 2023
The adult heart is made up of cardiomyocytes (CMs) that maintain pump function but are unable to divide and form new myocytes in response to myocardial injury.
Andrea Elia, Sadia Mohsin, Mohsin Khan
doaj   +1 more source

Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing

open access: yesAdvanced Science, EarlyView.
It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song   +8 more
wiley   +1 more source

Genome Size in the Arenaria ciliata Species Complex (Caryophyllaceae), with Special Focus on Northern Europe and the Arctic

open access: yesPlants
The main aim of the present study has been the completion of genome size data for the diverse arctic-alpine A. ciliata species complex, with special focus on the unexplored arctic taxon A. pseudofrigida, the north-European A. norvegica, and A.
Gregor Kozlowski   +9 more
doaj   +1 more source

Yield, structural composition and nutritive characteristics of ryegrass cultivars used to haymaking in lowland soils

open access: yesBioscience Journal, 2018
This research aimed to evaluate the dry matter yield, structural composition and nutritive characteristics of diploid and tetraploid annual ryegrass cultivars on different phenological development to haymaking on lowland soils.
Olmar Antônio Denardin Costa   +7 more
doaj   +1 more source

Comparative analysis of cell-free DNA content in culture medium and mitochondrial DNA copy number in porcine parthenogenetically activated embryos

open access: yesThe Journal of Reproduction and Development, 2020
We examined the effect of ploidy on mitochondrial DNA (mtDNA) copy number in embryos and the amount of cell-free mitochondrial and nucleic DNA content (cf-mtDNA and cf-nDNA) in spent culture medium (SCM).
Mitsuru KOBAYASHI   +4 more
doaj   +1 more source

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