Results 81 to 90 of about 88,719 (358)

Prognostic significance of DNA cytometry in cutaneous malignant lymphomas. [PDF]

, 1991
The current classification of cutaneous malignant lymphomas (ML) into low-grade and high-grade lymphomas was found to be of limited reproducibility and permitted only a rough prediction about outcome.
Abmayr, Wolfgang, Braun-Falco, Otto, Burg, Günter, Dummer, Reinhard, Eckert, Fritjof, Kaudewitz, Peter, Stolz, Wilhelm, Vogt, Thomas   +7 more
core   +1 more source

Recombining your way out of trouble: the genetic architecture of hybrid fitness under environmental stress [PDF]

, 2020
Hybridization between species is a fundamental evolutionary force that can both promote and delay adaptation. There is a deficit in our understanding of the genetic basis of hybrid fitness, especially in non-domesticated organisms.
Bendixsen, D., Greig, D., Janzen, T., Nolte, A., Stelkens, R., Zhang, Z.   +5 more
core   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

International Journal of Cancer, EarlyView.
What's New? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff, Christiane Schaefer, Wilhelm G. Dirks, Dawid Krzeciesa, Maximilian Bretschneider, Pauline R. Plaumann, Wiebke K. Guder, Arne Streitbürger, Sonja Herter, Heike Peterziel, Ina Oehme, Felina Zahnow, Thomas G. P. Grünewald, Uta Dirksen   +13 more
wiley   +1 more source

An Improved Natural Transformation Protocol for the Cyanobacterium Synechocystis sp. PCC 6803

Frontiers in Plant Science, 2020
The naturally transformable cyanobacterium Synechocystis sp. PCC 6803 is a widely used chassis strain for the photosynthetic production of chemicals. However, Synechocystis possesses multiple genome copies per cell which means that segregating mutations ...
Matthew A. Pope, Josh A. Hodge, Peter J. Nixon   +2 more
doaj   +1 more source

Variance of ploidy in Candida albicans [PDF]

Journal of Bacteriology, 1982
Determination of ploidy was performed on isolates of Candida albicans from clinical sources by measuring nuclear DNA content with fluorescent microscope photometry. By this criterion and UV irradiation survival experiments, haploid, diploid, and tetraploid strains were identified in this organism.
Takahito Suzuki, K Tanaka, S Nishibayashi, T Kuroiwa, T Kanbe   +4 more
openaire   +3 more sources

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Analysis of character of blooming and the some selection-valuable features of triticale (Triticale Wittm.) in the conditions of Southern Dagestan

Юг России: экология, развитие, 2015
The studying of character of blooming and of some selectionno-valuable signs of the newest cultivars triticale of various parentage and of ploidy level.
U. K. Kurkiev, K. U. Kurkiev, M. D. Dibirov, D. M. Anatov   +3 more
doaj   +1 more source

De Novo Whole Genome Assemblies of Unusual Case‐Making Caddisflies (Trichoptera) Highlight Genomic Convergence in the Composition of the Major Silk Gene (h‐fibroin)

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
The major silk gene, h‐fibroin, was annotated in high‐quality genomes of two unusual case‐making Trichoptera. H‐Fibroin of Limnocentropus insolitus shows a similar amino acid composition to other case‐making species, while the amino acid composition of h‐fibroin of Phryganopsyche brunnea resembles that of retreat‐making species.
Xiling Deng, Steffen U. Pauls, Ryoichi B. Kuranishi, Paul B. Frandsen, Jacqueline Heckenhauer   +4 more
wiley   +1 more source

Haploidy-linked cell proliferation defects limit larval growth in zebrafish

Open Biology
Haploid larvae in non-mammalian vertebrates are lethal, with characteristic organ growth retardation collectively called ‘haploid syndrome’. In contrast to mammals, whose haploid intolerance is attributed to imprinting misregulation, the cellular ...
Kan Yaguchi, Daiki Saito, Triveni Menon, Akira Matsura, Miyu Hosono, Takeomi Mizutani, Tomoya Kotani, Sreelaja Nair, Ryota Uehara   +8 more
doaj   +1 more source

Problems associated with the use of Heliantbus species for the breeding of the cultivated sunflower: Ploidy level or phylogenetic distance? [PDF]

Selekcija i Semenarstvo, 2000
Of the 49 species that comprise the genus Helianthus, 42 are present in the wild species collection at the Institute of Field and Vegetable Crops. This is a rich bank of desirable genes for sunflower breeders.
Atlagić Jovanka, Škorić Dragan
doaj