Results 81 to 90 of about 115,209 (391)

RanBALL: An Ensemble Machine Learning Framework for Accurate Subtype Identification of Pediatric B‐Cell Acute Lymphoblastic Leukemia

open access: yesAdvanced Intelligent Systems, EarlyView.
Here, we present RanBALL, an ensemble random projection‐based model for accurate and cost‐effective identification of B‐cell acute lymphoblastic leukemia subtypes is presented. By preserving patient‐to‐patient distance after dimension reduction by random projection and ensemble learning, RanBALL can facilitate the discovery of B‐ALL subtype‐specific ...
Lusheng Li   +6 more
wiley   +1 more source

Pangenomes as a framework for adaptive radiation, speciation, and adaptation

open access: yesAmerican Journal of Botany, EarlyView.
Abstract Understanding the genomic basis of diversification is a central goal in evolutionary biology. In recent years, the development and use of pangenomes, a genomic representation of multiple individuals within a lineage (a set of related populations, subspecies, ecotypes, or species), has enabled researchers to differentiate between DNA sequences ...
Nicolò Tellini   +5 more
wiley   +1 more source

Corrigenda: Bhowmick BK, Jha S (2022) A critical review on cytogenetics of Cucurbitaceae with updates on Indian taxa. Comparative Cytogenetics 16(2): 93–126. https://doi.org/10.3897/compcytogen.v16.i2.79033 [PDF]

open access: yesComparative Cytogenetics
The cytogenetic relationships in the species of Cucurbitaceae are becoming immensely important to answer questions pertaining to genome evolution. Here, a simplified and updated data resource on cytogenetics of Cucurbitaceae is presented on the basis of ...
Biplab Kumar Bhowmick, Sumita Jha
doaj   +3 more sources

Cardiomyocyte Ploidy, Metabolic Reprogramming and Heart Repair

open access: yesCells, 2023
The adult heart is made up of cardiomyocytes (CMs) that maintain pump function but are unable to divide and form new myocytes in response to myocardial injury.
Andrea Elia, Sadia Mohsin, Mohsin Khan
doaj   +1 more source

Flow Cytometry: Advances, Challenges and Trends

open access: yesBioEssays, EarlyView.
Recent advances in flow cytometry span hardware, data processing, and AI‐driven analytics. Emerging modalitiesincluding spectral, imaging, mass, and nano/EV cytometryenable higher‐parameter and small‐particle detection. Integrated machine learning drives a shift from manual gating toward automated multi‐omics workflows.
J. Paul Robinson   +2 more
wiley   +1 more source

Tetraploidy‐linked sensitization to CENP‐E inhibition in human cells

open access: yesMolecular Oncology, 2023
Tetraploidy is a hallmark of cancer cells, and tetraploidy‐selective cell growth suppression is a potential strategy for targeted cancer therapy. However, how tetraploid cells differ from normal diploids in their sensitivity to anti‐proliferative ...
Koya Yoshizawa   +14 more
doaj   +1 more source

Mastering DNA Content Estimation by Flow Cytometry as an Efficient Tool for Plant Breeding and Biodiversity Research

open access: yesMethods and Protocols, 2023
Flow cytometry gives a unique opportunity to analyze thousands of individual cells for multiple parameters in a course of minutes. The most commonly used flow cytometry application in plant biology is estimation of nuclear DNA content.
Maria Fomicheva, Elena Domblides
doaj   +1 more source

Adaptation of the guayule to Mediterranean climate: characterization and enhancement of genetic diversity [PDF]

open access: yes, 2019
The objective of Agroguayule project (co-financing ADEME, Call for projects GRAINE) is to select lines that combine good adaptation to the Mediterranean climate (dry and cold), high vegetative vigour and a high concentration in natural rubber.
Bakry, Frédéric   +6 more
core  

Dosage Sensing, Threshold Responses, and Epigenetic Memory: A Systems Biology Perspective on Random X‐Chromosome Inactivation

open access: yes, 2020
X‐chromosome inactivation ensures dosage compensation between the sexes in mammals by randomly choosing one out of the two X chromosomes in females for inactivation.
Barr M. L.   +4 more
core   +1 more source

Niche divergence and limits to expansion in the high polyploid Dianthus broteri complex [PDF]

open access: yes, 2019
Niche evolution in plant polyploids remains controversial and evidence for alternative patterns has been reported. Using the autopolyploid Dianthus broteri complex (2×, 4×, 6× and 12×) as a model, we aimed to integrate three scenarios – competitive ...
Balao Robles, Francisco J.   +2 more
core   +1 more source

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