Results 81 to 90 of about 35,320 (237)

Fascinating single‐cell red algae: models for evolution and adaptation

New Phytologist, EarlyView.
Summary The unicellular red algae, Cyanidiophyceae, that diverged early during Archaeplastida (algal and plant) evolution, occupy a variety of extreme habitats that are inhospitable for most other eukaryotes. With the use of modern genomics and genetics methods, Cyanidiophyceae show a remarkable taxonomic diversity, share haplodiplophasic life cycles ...
Frédéric Berger, Debashish Bhattacharya, Chung Hyun Cho, Seok‐Wan Choi, Julia Van Etten, Shunsuke Hirooka, Tzu‐Yen Huang, Kyle J. Lauersen, Yongsung Lee, Shao‐Lun Liu, Shin‐ya Miyagishima, Stephen D. Rader, Daniel Schubert, Hwan Su Yoon   +13 more
wiley   +1 more source

Ensemble-Based Refinement of Landmark Annotations for DNA Ploidy Analysis in Digital Pathology

Applied Sciences
Reliable evaluation of image segmentation algorithms in digital pathology depends on high-quality annotation datasets. Landmark-type annotations, essential for cell-counting analyses, are often limited in quality or quantity for segmentation benchmarking,
Viktor Zoltán Jónás, Dániel Küttel, Béla Molnár, Miklós Kozlovszky   +3 more
doaj   +1 more source

Random Mutagenesis in Porphyromonas gingivalis Enables Isolation of Mutants With Enhanced Secreted Protease Activity

Molecular Oral Microbiology, EarlyView.
ABSTRACT Porphyromonas gingivalis is a key pathogen in periodontitis, with secreted proteases as major virulence factors. We developed a screening method to generate and identify P. gingivalis mutants with elevated protease activity. Mutations were induced using the mutagens 2,6‐diaminopurine (2,6‐DAP) or ethyl methanesulfonate (EMS), and the ...
Takeru Nakabayashi, Satoshi Yuhara, Kosei Tanaka   +2 more
wiley   +1 more source

Rapid Genetic Stabilisation of Transgenic and Edited Wheat Through Transformation of Immature Haploid Embryos

Plant Biotechnology Journal, EarlyView.
ABSTRACT Wheat is one of the globally important food crops, but its genetically modified application lags behind other staple crops due to its complex genome and low transformation efficiency. Normally, traditional transgenic and gene‐edited wheat requires multiple selfing generations for obtaining homozygous lines, which delayed the development of ...
Zhiyang Han, Buquan Zhao, Ming Fan, Shuangxi Zhang, Hao Peng, Xi Li, Surong Wang, Weihong Huang, Xingyu Yao, Chunwu Yang, Ke Wang, Xingguo Ye, Huali Tang   +12 more
wiley   +1 more source

Exploring the intratumoral heterogeneity of DNA ploidy in prostate cancer

Cancer Reports
Background Prostate cancer is morphologically and molecularly heterogeneous. Genomic heterogeneity might be mirrored by variability in DNA ploidy. Aneuploidy is a hallmark of genomic instability and associated with tumor aggressiveness.
Tatjana Vlajnic, David C. Müller, Christian Ruiz, René Schönegg, Hans‐Helge Seifert, George N. Thalmann, Tobias Zellweger, Clémentine Le Magnen, Cyrill A. Rentsch, Lukas Bubendorf   +9 more
doaj   +1 more source

Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50‐JAZ5 Module

Plant Biotechnology Journal, EarlyView.
ABSTRACT Colletotrichum spp., hemibiotrophic fungal pathogens, threaten global strawberry production. Jasmonate (JA) regulates plant‐Colletotrichum interactions, but its mechanisms remain unclear. Here we demonstrate that both exogenous methyl jasmonate (MeJA) treatment and elevated endogenous MeJA levels increase strawberry susceptibility to ...
Chuang Liu, Zhen Liu, Xia Li, Yating Chen, Ronghui Sun, Peijie Li, Qianqian Feng, Yuanhua Wang, Jie Ren, Qian Li, Bingbing Li   +10 more
wiley   +1 more source

Exceptional Uptake, Limited Protein Expression: Liver Macrophages Lost in Translation of Synthetic mRNA

Advanced Science
Most gene therapies exert their actions via manipulation of hepatocytes (parenchymal cells) and the reasons behind the suboptimal performance of synthetic mRNA in non‐parenchymal cells (NPC) such as Kupffer cells (KC), and liver macrophages, remain ...
Cheng Lin, Adrian Kuzmanović, Nan Wang, Liangliang Liao, Sabrina Ernst, Christian Penners, Alexander Jans, Thomas Hammoor, Petra Bumnuri Stach, Mona Peltzer, Ines Volkert, Elisabeth Zechendorf, Reham Hassan, Maiju Myllys, Christian Liedtke, Andreas Herrmann, Gurudas Chakraborty, Christian Trautwein, Jan Hengstler, Gerhard Müller‐Newen, Junqing Wang, Ahmed Ghallab, Matthias Bartneck   +22 more
doaj   +1 more source

TaPHL7 Transcription Factor Regulates Utilisation of Nitrogen and Phosphorus in Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT Macronutrients nitrogen and phosphorus are essential for plant growth and development, thus being crucial for the productivity of crops. However, the molecular mechanism regulating the utilisation of nitrogen and phosphorus remains elusive. Here, we show that the wheat (Triticum aestivum L.) transcription factor PHOSPHATE STARVATION RESPONSE ...
Huali Wang, Zhiyong Zhang, Yafei Guo, Qing Wang, Xiaochun Wang, Xiaohui Ma, Jinqiang Nian, Shuping Xiong, Xinbo Lin, Yingyin Yao, Zhongfu Ni, Fei Lu, Jianru Zuo, Xinming Ma   +13 more
wiley   +1 more source

DETERMINATION OF THE ORIGIN OF REGENERATED FLAX PLANTS IN ANTHER CULTURE

Вавиловский журнал генетики и селекции, 2014
The possibility to diagnose the ploidy of cells producing regenerated plants in vitro in anther culture has been studied. It is shown by the example of oil flax that population analysis of regenerated plants for segregation on the basis of a marker trait
A. I. Soroka, V. A. Lyakh
doaj  

Haploid Mutation Mapping Identifies a Homoeologous Non‐Reciprocal Translocation Linked to Reduced Fibre and Enhanced Protein in Brassica napus

Plant Biotechnology Journal, EarlyView.
ABSTRACT A key challenge for the genetic improvement of canola (Brassica napus), one of the world's most important oilseeds, is the limited natural variation for commercially important traits. The creation of new variation is hindered by the lack of functional knowledge about genes controlling these traits.
Morgan W. Kirzinger, Sarika Saini, Andrea T. Todd, Ushan Alahakoon, Kevin C. Koh, Justin B. Nichol, HaiYing Yuan, Kevin Fengler, Victor Llaca, Dustin Cram, Sampath Perumal, Wali Soomro, Magda Konopka, Tancey Melchkart, Venkat Bandi, Yasmina Bekkaoui, Yifang Tan, Chad Matsalla, Andrew G. Sharpe, Carl Gutwin, Fred Thoonen, Igor Falak, Chad Koscielny, Stuart Gardner, Isobel A. P. Parkin, Marcus A. Samuel, Alison M. R. Ferrie, Dave Charne, Daoquan Xiang, Jetty S. S. AmmiRaju, Sateesh Kagale   +30 more
wiley   +1 more source