Results 101 to 110 of about 8,480,042 (327)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Close to the edge: High productivity at plot peripheries and the inverse size-productivity relationship

Journal of Development Economics, 2020
Smaller farms and plots appear more productive per hectare than larger ones in most developing country data. Using unique plot-level panel data from Uganda, with agricultural plots matched over a decade using geospatial location, we estimate the size ...
Leah E M Bevis, C. Barrett
semanticscholar   +1 more source

Uniformity trials size for estimating cherry tomato plot size

, 2018
The aim of this study was to determine how the size of the uniformity trial influences the estimation of cherry tomato plot size. The size of plot required to evaluate the mean length of fruit per plant, mean fruit width per plant, mean fruit weight per ...
Bruno Giacomini Sari (5717021), Alessandro Dal'Col Lúcio (5835800)   +1 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Aleatoriedade e variabilidade produtiva de feijão-de-vagem Randomness and variability productive of bean pod

Ciência Rural, 2012
Com o objetivo de estudar a aleatoriedade e a variabilidade produtiva de feijão-de-vagem, foram realizados os seguintes experimentos em branco: 1) em estufa no outono-inverno; 2) em túnel no outono-inverno; 3) em ambiente não protegido no outono-inverno;
Daniel Santos, Fernando Machado Haesbaert, Alessandro Dal'Col Lúcio, Sidinei José Lopes, Alberto Cargnelutti Filho, Vilson Benz   +5 more
doaj  

Optimal plot size for experimental trials with Opuntia cactus pear

Acta Scientiarum: Technology, 2019
The objective of the study with `Gigante´ cactus pear was to determine the size of plots that optimize the implementation of experiments with greater accuracy, spatial adequacy and efficiency of use of the experimental area by the Hatheway method (1961).
Bruno Viní­cius Castro Guimarães, Sérgio Luiz Rodrigues Donato, Ignacio Aspiazú, Alcinei Mí­stico Azevedo, Abner José de Carvalho   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The effect of the calculation method, plot size, and stand density on the accuracy of top height estimation in Norway spruce stands

, 2017
: The aim of this study was to evaluate top height (TH) estimates for Norway spruce stands calculated according to different computational methods, and to assess the effects of stand density and plot size on TH estimation accuracy.
W. Ochał, J. Socha, M. Pierzchalski
semanticscholar   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source