S‐Adenosyl‐d‐Methionine as a Non‐Physiological Substrate for a Wide Range of SAM‐Dependent Enzymes
From methylation and cyclisation to radical chemistry, diverse enzyme classes utilise the non‐canonical cofactor d‐SAM. These findings reveal an unexpected tolerance of SAM‐dependent catalysis towards inversion of the methionine Cα stereocentre. The ability of SAM‐dependent enzymes to accept S‐adenosyl‐d‐methionine [d‐SAM, (SS,RCα)‐SAM] instead of the ...
Philipp Germer +17 more
wiley +1 more source
A whole‐cell biocatalytic cascade in engineered Escherichia coli RARE couples the ω‐transaminase from Pseudomonas psychrotolerans with pyruvate decarboxylase from Zymomonas mobilis to shift transamination toward amine formation via pyruvate removal. Integration of the cascade into a chemo‐enzymatic synthesis pathway enables the scalable production of 2,
Laura Edit Barabás +5 more
wiley +1 more source
Calcitonin as an adjunct for phantom limb pain. [PDF]
Vidyasagar S +3 more
europepmc +1 more source
Outcomes Following Targeted Muscle Reinnervation in Pediatric Amputations: A Systematic Review. [PDF]
Giuffre MJ +6 more
europepmc +1 more source
Incidence of Clinically Documented Phantom Limb Pain During Hospitalization and Preoperative Risk Factors in Patients Who Underwent Nontraumatic Major Lower Limb Amputation: A Single-Center, Retrospective Study. [PDF]
Mieda T +10 more
europepmc +1 more source
Resting-State Theta and Alpha Oscillations in Amputation and Phantom Limb Pain: A Pre-Registered High-Density EEG Study. [PDF]
Ramne M, Lendaro E.
europepmc +1 more source
Electrostatic tuning of the pyridoxal-5'-phosphate cofactor site defines pH dependence in type I cystathionine β-lyases. [PDF]
Liu Y +12 more
europepmc +1 more source
Probabilistic logic programming (PLP) 2016
Arjen Hommersom, James Cussens
openaire +1 more source
Effect of Short-Anchored PEGylated Lipids on Lipid Nanoparticle Characterization Profiles, Stability, and Efficacy. [PDF]
Souleyrette CER +9 more
europepmc +1 more source
The association between quality of life, anxiety and depression, and residual limb and phantom limb pain in war-related amputees: a year-long observational study. [PDF]
Smolynets R +3 more
europepmc +1 more source

