Results 101 to 110 of about 7,364 (206)
The effects of plumbagin on proliferation and metastasis in human liver cancer SK-hep-1 cells
Background and purpose: Plumbagin is the main active components of traditional Chinese medicine of plumbago zeylanica. The present studies show that plumbagin has a killing effect on tumor cells.
曹晓淬 +4 more
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Development of a new inhibitor of BCR-ABL tyrosine kinase is necessary for the treatment of chronic myeloid leukemia (CML) because of increasing resistance and tolerance to Imatinid efforts.
Bui Thi Kim Ly +3 more
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Plumbagin Suppresses Pulmonary Fibrosis via Inhibition of p300 Histone Acetyltransferase Activity
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing interstitial lung disease with a poor prognosis similar to that of malignancy. The causes of IPF are not clearly known, and there is no effective therapy to date.
손명현 +4 more
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The glucose regulated protein 78 (GRP78) is a major chaperone of the endoplasmic reticulum, and a prosurvival component of the unfolded protein response. GRP78 is upregulated in many types of cancers, including breast cancer.
Anna Jaworska +3 more
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Purpose: To investigate the protective effects of plumbagin against liver fibrosis and explore the influence of plumbagin on the proliferation of hepatic stellate cells (HSCs).
Zhao, Tiejian +6 more
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Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers, and it requires novel treatment approaches and effective drugs. In the present study, we found that treatment with plumbagin, a natural compound, reduced proliferation and ...
Ting-Ting Liu +11 more
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Niosomal Plumbagin with Reduced Toxicity and Improved Anticancer Activity in BALB/C Mice
Plumbagin niosomes were prepared using a lipid layer hydration method, and drug entrapment was measured. The acute toxicity studies were conducted following treatment with free and niosomal plumbagin.
N Udupa, R A Raja Naresh, P Uma Devi
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Introduction: Bioactive elements present in distinct medicinal plants and foods are appealing molecules for the evolution of novel medications for the treatment of multiple illnesses linked with inflammation and oxidative stress.
Aanchal Verma, Ahsas Goyal
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Development of tumour-targeted delivery systems entrapping plumbagin for cancer therapy
This thesis was previously held under moratorium from 22 August 2019 until 22 August 2024.Plumbagin, a naphthoquinone mainly extracted from Plumbaginaceae plants, has been shown to have promising anti-cancer properties. However, its therapeutic potential
Sakpakdeejaroen, Intouch
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[Harmlessness of plumbagine in a biological experiment].
Plumbagine (2-methyl-5-oxy-1,4-naphtoquinone) did not have any essential effect on the general condition and dynamic changes in the body mass of albino rats, their blood coagulation system and fibrinolysis, the liver and renal functions and morphological structure of the internal organs. An analysis of the available data justify recommending plumbagine
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