Results 91 to 100 of about 7,364 (206)
Plumbagin Induces Cell Cycle Arrest and Apoptosis in A431 Cisplatin-Resistant Cancer Cells
Natural Product Communications, 2020 The onset of drug resistance represents the leading cause of chemotherapy failure in clinics. In the last decades, natural compounds have emerged as possible anticancer strategies used either alone or in combination with chemotherapeutic drugs, in order ...
Isabella Giacomini +4 more
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International Journal of Nanomedicine, 2011 Priya Srinivas1,2, Chitta Ranjan Patra2,4, Santanu Bhattacharya2, Debabrata Mukhopadhyay2,31Integrated Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Kerala, India; 2Department of Biochemistry and Molecular Biology; 3Department of ...
Srinivas P +3 more
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Extension of lifespan in C. elegans by naphthoquinones that act through stress hormesis mechanisms.
PLoS ONE, 2011 Hormesis occurs when a low level stress elicits adaptive beneficial responses that protect against subsequent exposure to severe stress. Recent findings suggest that mild oxidative and thermal stress can extend lifespan by hormetic mechanisms.
Piper R Hunt +10 more
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Enhancement of lipid peroxidation in wild-type and Gtt deficient cells caused by plumbagin.
, 2013 The increase in lipid peroxidation was expressed as a ratio between the levels of lipid peroxidation of plumbagin stressed and non-stressed cells. Yeast cells, harvested in mid log phase, were directly stressed with 7.0 μM plumbagin (white bars) or were ...
Marcos Dias Pereira (375429) +4 more
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Investigation of Acid-Base Indicator Property of Plumbagin from Plumbago zeylanica Linn
International Journal of Analytical Chemistry, 2019 There has been an increasing interest in the search for colour indicators of natural origin for titrimetric analysis. This is due to some challenges associated with the currently used synthetic ones.
Emmanuel B. A. Adusei +3 more
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Biotemas, 2017 The aim of this study was to evaluate functionally the effect of plumbagin on the heterologous expression of a predicted promoter region of open reading frames of paraquat-inducible (pqi) genes revealed during genome annotation analyses of the bacterium ...
Jane Eyre Gabriel +3 more
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Plumbagin activates ERK1/2 and Akt via superoxide, Src and PI3-kinase in 3T3-L1 cells
, 2010 [[abstract]]Plumbagin, derived from the plant Plumbago zeylanica, has been shown to chronically activate ERK1/2 and inhibit Akt activity in cancer cells. However, the acute effects of plumbagin on ERK1/2 and Akt activities remain unknown.
Yang, SJ;Chang, SC;Wen, HC;Chen, CY;Liao, JF;Chang, CH
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Lipid peroxidation in plumbagin administered rats
Journal of Biosciences, 1987 Plumbagin was administered to rats at a concentration of 1,2,4,8 and 16 mg per kg body weight. After 24 h lipid peroxide levels were found to decrease in subcellular fractions of liver. Plumbagin inhibited ascorbate and nicotinafde adenine dinucleotide phosphate (reduced) dependent lipid peroxidation but was without any effect on cumene hydroperoxide ...
R. Sankar +4 more
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PlantsPlumbago indica L. contains a valuable bioactive compound called plumbagin. Elicited regenerated shoots grown in vitro could be another source of high-yielding plumbagin.
Yaowapha Jirakiattikul +4 more
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Pharmacological effect of plumbagin in murine and human prostate cancer cell models
reservedAccording to the International Agency for Research on Cancer (IARC), prostate cancer (PC) is the second most spread tumor worldwide. The disease is characterized by an abnormal cell division rate of the prostate gland, which is functional in men
PULIAFITO, ANNA
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