Results 71 to 80 of about 7,364 (206)
Protein Science, Volume 35, Issue 1, January 2026.Abstract Repair of Iron Centers (RIC) proteins are present in several pathogens, including Staphylococcus aureus, contributing to resistance to nitroxidative stress and virulence. In this work, we investigated the molecular mechanisms by which S. aureus RIC facilitates iron mobilization, through structural analyses and functional studies.
Frederico M. Lourenço +8 more
wiley +1 more source
S. cerevisiae tolerance to plumbagin.
, 2013 Yeast cells harvested in mid log phase, were directly stressed with 7.0 μM plumbagin (white bars) or were previously treated with 0.5 μM plumbagin/1 h and then submitted to severe stress conditions (black bars).
Marcos Dias Pereira (375429) +4 more
core +1 more source
BMC Complementary and Alternative Medicine, 2011 Background The extracts of Plumbago zeylanica have been used in China and other Asian countries as folk medicine for the treatment of cancer, rheumatoid arthritis and dysmenorrhoea.
Poosarla Aparanji +3 more
doaj +1 more source
IET Nanobiotechnology, Volume 2026, Issue 1, 2026.Human islet amyloid polypeptide (hIAPP) oligomers, formed through an accumulation pathway, are toxic to insulin‐secreting pancreatic β‐cells and are considered to contribute for β‐cell death and insulin deficiency commonly observed in type 2 diabetes (T2D) patients.
Mahboobeh Nazari +8 more
wiley +1 more source
Role of COX-2 in resistance to Plumbagin induced apoptosis.
, 2013 a.i. Cytotoxicity effect of various concentrations of Plumbagin on COX-2 silenced HT29 cells. Dose dependent cytotoxicity effects of Plumbagin on HCT15 cells were represented in the above graph.
Devaraj Halagowder (76131) +6 more
core +1 more source
Antimicrobial activity in vitro of plumbagin isolated from Plumbago species
, 2003 Plumbagin is a naturally occurring naphthoquinone isolated from roots of Plumbago scandens. The plant was collected at the Campus of Fundação Oswaldo Cruz, Rio de Janeiro, Brazil. P. scandens is used as a traditional medicine for the treatment of several
Maria Raquel Figueiredo +7 more
core +2 more sources
Figure 8D Inhibition of SaTrmK by plumbagin
, 2022 MSMS fragmentation data of SaTrmK and plumbagin incubated SaTrmK gluC/trypsin digest.
Rafael Guimaraes da Silva (12088874) +2 more
core +1 more source
Crystal structure of Methanococcus jannaschii dihydroorotase with substrate bound
Acta Crystallographica Section F, Volume 82, Issue 1, Page 23-31, January 2026.We present the 1.87 Å resolution structure of M. jannaschii dihydroorotase complexed with the substrate carbamoyl aspartate at room temperature. Contrary to expectations, a flexible loop which is important in catalysis and closes upon substrate binding in order to stabilize the substrate and transition state is observed in both the loop‐out and loop‐in
Jacqueline Vitali +3 more
wiley +1 more source
Diagram depicting mode of action of plumbagin.
, 2012 Diagram depicting mode of action of plumbagin.
Ji-Hyun Yeon (135454) +6 more
core +1 more source
PLoS ONE, 2020 Plumbagin derived from the plant Plumbago indica, known as Chitrak in India, is an example of a medicinal compound used traditionally to cure a variety of ailments.
Apurba Sarkar +6 more
doaj +1 more source