Results 51 to 60 of about 7,364 (206)

Anticancer Activity of Copolymeric Nanoparticles Loaded by Plumbagin on Breast Cancer cells

مجله دانشگاه علوم پزشکی گرگان, 2022
Background and Objective: In medical sciences, identifying the anticancer properties of plumbagin is of special importance. For this reason, this study investigated the anticancer activity of polymeric nanoparticles loaded by plumbagin against breast ...
Hossein Danafar, Ali Sharafi, Behrouz Parnianifar   +2 more
doaj  

Downstream Pathways of Dystrophin Deficiency in Duchenne Muscular Dystrophy: Implications for Muscle Degeneration and Regeneration

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) is the most common and severe form of muscular dystrophy, primarily affecting skeletal muscle and leading to premature death. Although the loss of dystrophin has long been recognised as the primary cause of the disease, no definitive cure is currently available. As a consequence, therapeutic efforts
Raffaele Epis, Gabriele Rovetta, Giulia Ferrari, Chiara Bonfanti, Giorgia Careccia, Graziella Messina   +5 more
wiley   +1 more source

Synthesis of Some Plumbagin Derivatives and Their Antibacterial Activity. [PDF]

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Saradha Vasanth, K. Balakrishna, N. K. George, G. Veluchamy   +3 more
openaire   +2 more sources

Dietary Polyphenols as Natural Modulators of NF‐κB Signaling in Inflammation‐Driven Non‐Communicable Diseases: Focus on Cancer

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam, Anas Shamsi, Syed Tasqeruddin, Moyad Shahwan   +3 more
wiley   +1 more source

Structure activity relationship of plumbagin in BRCA1 related cancer cells

, 2013
It has been shown earlier that plumbagin, a naturally occurring naphthaquinone has specific anticancer activity in BRCA1 blocked ovarian cancer cells. Plumbagin can induce estrogen dependent cell signaling and apoptosis in BRCA1 blocked ovarian cancer ...
Ratheeshkumar, T, Banerji, A, Rojini, G, Somasundaram, V, Srinivas, G, Srinivas, P, Thasni, KA, Sivakumar, KC, Nair, RS   +8 more
core   +1 more source

Discovery of pseudobaptigenin synthase in fungal‐infected Trifolium pratense roots

The Plant Journal, Volume 127, Issue 1, July 2026.
Significance Statement The discovery of pseudobaptigenin synthase in red clover (CYP76F319), catalyzing the formation of a methylenedioxy bridge to convert calycosin to pseudobaptigenin. The integration of metabolomic and transcriptomic datasets to describe the defense response in red clover roots to hemibiotrophic and necrotrophic fungi.
Lee Marie Raytek, Lan Liu, Stéphane Bayen, Mehran Dastmalchi   +3 more
wiley   +1 more source

Discovery of a Novel γ‐Glutamylcyclotransferase Inhibitor Plumbagin by Luminescence‐Based High‐Throughput Screening

Cancer Science, Volume 117, Issue 6, Page 1713-1723, June 2026.
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi, Yukie Nohara, Mano Horinaka, Kozue Nose, Masaya Mori, Hiromi Ii, Hiroko Kawakami, Kazuto Yano, Susumu Nakata, Taku Yoshiya, Toshiyuki Sakai   +10 more
wiley   +1 more source

Effect of Plumbagin on Colonic cancer cells and normal PBMCs.

, 2013
a. Cytotoxicity effect of various concentrations of Plumbagin on HCT15 cells. Dose dependent cytotoxicity effects of Plumbagin on HCT15 cells were represented in the above graph. HCT15
Devaraj Halagowder (76131), Gayathri Srinivasan (308717), Lakshmi Baddi Reddi Subhadara (352254), Sakeena Sadullah Mohammed Sadullah (352252), Niranjali Devaraj Sivasitambaram (352255), Bharathi Raja Subramaniya (352251), Nimitha Davis (352253)   +6 more
core   +1 more source

Plant‐Derived Treatments for Monogenean Parasites in Farmed Fish: A Systematic Review and Meta‐Analysis

Reviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Monogeneans are among the most problematic ectoparasites in finfish aquaculture. Plant‐derived compounds have been widely explored as therapeutic agents, yet their efficacy and safety have not been quantitatively synthesized across studies. This study provides a meta‐analysis of plant‐based treatments against monogeneans, integrating 453 in ...
Francisco Neptalí Morales‐Serna
wiley   +1 more source

Exploitation of the antifungal and antibiofilm activities of plumbagin against Cryptococcus neoformans

, 2022
Cryptococcus neoformans is an important opportunistic fungal pathogen that causes various infections. Here, the antifungal and antibiofilm activities of plumbagin against C. neoformans and the underlying mechanisms were evaluated.
Jianing Zhang (283045), Yuting Fu (735039), Ting Wang (16292), Weidong Qian (10738113), Wenjing Wang (181404), Xinchen Li (12571084), Qiming Liu (3343259), Qian Zhang (49333)   +7 more
core   +1 more source