Results 31 to 40 of about 7,364 (206)
Journal of Pharmacological Sciences, 2017 Plumbagin is a natural naphthoquinone constituent isolated from the roots of medicinal plant Plumbago zeylanica L., and has demonstrated anti-proliferative and anti-invasion activities in various cancer cells.
Guanghui Chen +5 more
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Bioresources and Bioprocessing, 2020 The simultaneous and sequential dual elicitation effect on plumbagin production in Plumbago indica L. root cultures, revealed that combination of chitosan (150 mg L−1) with ʟ-alanine (5 mM) or methyl-β-cyclodextrin (MCD; 2 mM) significantly increased ...
Amit Jaisi +1 more
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ANTIFUNGAL PROPERTIES OF PLUMBAGIN
Journal of the National Science Foundation of Sri Lanka, 2002 Key Words: Agro-well, sustainable irrigation, water shortage, well dimension Doi:10.4038/jnsfsr.v30i3-4.2498 J. Natn. Sci.
Adikaram, N.K.B. +5 more
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IET Nanobiotechnology, 2015 Colloidal silver nanoparticles (AgNPs) have attracted much attention in recent years as diagnostics and new drug delivery system in cancer medicine. To study the effects of plumbagin (PLB), a relatively non‐toxic napthaquinone isolated from the roots of Plumbago indica in human cervical ...
Prakash, Appadurai +1 more
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Plumbagin Prevents Secretory Diarrhea by Inhibiting CaCC and CFTR Channel Activities
Frontiers in Pharmacology, 2019 Secretory diarrhea, which primarily originates through intestinal pathogens and viruses, is a health burden in many regions worldwide. Enterocyte Cl− channels, as the final step in enterotoxin-induced fluid secretion, constitute an attractive class of ...
Bo Yu +6 more
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Current Research in Pharmacology and Drug Discovery, 2022 Background: Plumbagin, a natural phenolic compound is investigated for response against blood pressure and vascular reactivity. Methodology: Blood pressure lowering effects were observed by in-vivo invasive evaluation in normotensive rats, and in-vitro ...
Maira Ahmad +3 more
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Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells
Scientific Reports, 2019 The Na+/K+-ATPase (NKA) complex is the master regulator of membrane potential and a target for anti-cancer therapies. Here, we investigate the effect of drug-induced oxidative stress on NKA activity.
Yousef Alharbi +6 more
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PLoS ONE, 2014 Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is a naphthoquinone derivative from the roots of plant Plumbago zeylanica and belongs to one of the largest and diverse groups of plant metabolites.
Mohammad S Jamal +7 more
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Antimalarial activity of plumbagin in vitro and in animal models [PDF]
BMC Complementary and Alternative Medicine, 2014 Abstract Background Plumbagin is the major active constituent in several plants including Plumbago indica Linn. (root). This compound has been shown to exhibit a wide spectrum of biological and pharmacological activities.
Sumsakul, Wiriyaporn +5 more
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Plumbagin protects against hydrogen peroxide-induced neurotoxicity by modulating NF-κB and Nrf-2
Archives of Medical Science, 2016 Introduction : Redox signaling initiates pathogenesis of neuronal degeneration. Plumbagin is a potential antioxidant with anti-inflammatory, anti-cancer and radio sensitizing properties.
Wang Kuan-hong, Li Bai-zhou
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