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Insecticidal activity and underlying molecular mechanisms of a phytochemical plumbagin against Spodoptera frugiperda [PDF]
Frontiers in PhysiologyIntroductionPlumbagin is an important phytochemical and has been reported to exhibit potent larvicidal activity against several insect pests, However, the insecticidal mechanism of plumbagin against pests is still poorly understood.
Xiaoyu Sun +7 more
doaj +2 more sources
Plumbagin induces testicular damage via mitochondrial-dependent cell death
, 2021 Different aspects of reproductive functions are regulated by mitochondrial-controlled events. This study investigated the effect of plumbagin (PL) on testicular mitochondria with a view to unravelling the mechanism of the antifertility potential of ...
Oyebode, O. +4 more
core +1 more source
The phytochemical plumbagin reciprocally modulates osteoblasts and osteoclasts [PDF]
Biological Chemistry, 2021 Abstract Bone metabolism is essential for maintaining bone mineral density and bone strength through a balance between bone formation and bone resorption. Bone formation is associated with osteoblast activity whereas bone resorption is linked to osteoclast differentiation.
Avinash M. Yadav +6 more
openaire +2 more sources
Design and development of plumbagin loaded poly (ε -caprolactone) nanoparticles for improved cytotoxicity [PDF]
Nanomedicine Research Journal, 2020 Poly (ε -caprolactone) nanoparticles were investigated as an injectable nanocarrier for the delivery of natural anticancer naphthoquinones plumbagin with the primary aim of improvement in its solubility, drug release profile and in vitro cytotoxicity ...
Harshad Kapare +2 more
doaj +1 more source
Plumbagin: a natural product for smart materials? [PDF]
New Journal of Chemistry, 2010 The exploitation of the natural product plumbagin (5-hydroxy-2-methyl-1,4- naphthoquinone) to produce polymer films capable of serving as controllable source of reactive oxygen species is assessed. The efficacy of the film to catalyse the reduction of oxygen to yield reactive oxygen species has been evaluated through using ascorbate and glutathione ...
Newton, LAA +4 more
openaire +1 more source
Fungal endophytes of Plumbago zeylanica L. enhances plumbagin content
Botanical Studies, 2019 Background Plumbagin is one of the pharmaceutically important biomolecule with anticancer potential. Among the plants reported to produce plumbagin, P. zeylanica topped the list.
Namdeo B. Andhale +2 more
doaj +1 more source
Current Research in Behavioral Sciences, 2021 Plumbagin (5‑hydroxy-2-methyl-1,4-naphthoquinone), a phytoconstituent has been shown to exhibit potent antioxidant and anti-inflammatory effects.
Ashok Jangra +4 more
doaj +1 more source
Frontiers in Immunology, 2019 Objective: Plumbago zeylanica L. (with plumbagin as its active ingredients) has been used for centuries to treat conditions such as joint swelling, fractures, and bacterial infections, suggesting that it possesses anti-inflammatory and immunosuppressive ...
Tingyu Wang +9 more
doaj +1 more source
Plumbagin Extraction: A Green Study
Natural Product Communications, 2023 A green study was undertaken for the extraction of plumbagin, an important natural naphthoquinone, from the roots of Plumbago pulchella Boiss. In the first stage, four solvents were comparatively evaluated, acetone, n-hexane, ethyl acetate, and methanol; attending Principle #5, only green solvents (ethyl acetate and acetone) were underscored.
Fernanda I. Calzada-González +5 more
openaire +1 more source
Research hotspots and trends of plumbagin: A bibliometric perspective. [PDF]
Medicine (Baltimore)Plumbagin is a biologically active naphthoquinone compound. Research related to plumbagin has gained popularity, evidenced by a gradual increase in publications. However, a bibliometric study in this field has yet to be conducted. Consequently, this study aims to evaluate the global scientific output of plumbagin research through bibliometric analysis,
Xu Z +7 more
europepmc +3 more sources