Results 81 to 90 of about 21,447 (213)

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

open access: yesAdvanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung   +39 more
wiley   +1 more source

Hydrothermal vents supporting persistent plumes and microbial chemoautotrophy at Gakkel Ridge (Arctic Ocean)

open access: yesFrontiers in Microbiology
Hydrothermal vents emit hot fluids enriched in energy sources for microbial life. Here, we compare the ecological and biogeochemical effects of hydrothermal venting of two recently discovered volcanic seamounts, Polaris and Aurora of the Gakkel Ridge, in
Gunter Wegener   +17 more
doaj   +1 more source

Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob

open access: yesAdvanced Science, EarlyView.
Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang   +7 more
wiley   +1 more source

Simulations and Analyses of the Influence of a Vacuum Back-Pressure Environment on Laser Ablation Thrusters

open access: yesAerospace
The study of thruster plume flow fields can yield a series of thruster performance parameters such as thrust effect, spacecraft plume contamination, etc., which is of great significance for thruster development.
Ming Wen   +3 more
doaj   +1 more source

Discovering Early‐Stage Gas Generation Kinetics Enables Thermal Runaway Early Warning in Lithium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
Operando gas diagnostics reveal a previously unrecognized chemical activation (CA) stage during thermal runaway in lithium‐ion batteries. A physics‐informed gas generation kinetics network (GGKNet) is developed to reconstruct reaction pathways and physical models automatically.
Jiabo Zhang   +6 more
wiley   +1 more source

An Efficient Detection Platform Based on Mesoporous Au@Cr2O3 Particles with Schwarz P Surface for Precise Periodontitis Metabolite Profiling

open access: yesAdvanced Science, EarlyView.
A non‐invasive periodontitis diagnosis platform was developed using Au nanoparticles‐decorated mesoporous Cr2O3 (Au@mCr2O3) particles with Schwarz P surface as matrix for saliva metabolic fingerprinting (SMFs) analysis via MALDI‐MS. With the assistance of machine learning of SMFs, this platform enables efficient diagnosis and the screening of potential
Yue Sun   +9 more
wiley   +1 more source

PALEOZOIC INTRAPLATE MAGMATISM OF THE EAST EUROPEAN PLATFORM: COMPARATIVE ANALYSIS OF THE PRIPYAT-DNIEPER-DONETS RIFT ZONE AND THE KOLA-ARKHANGELSK PROVINCE

open access: yesГеодинамика и тектонофизика
This paper presents a comparative analysis of geochronological, geochemical, Sr-Nd isotopic data and geodynamic conditions for the Devonian magmatism of the East European Platform, using as an example the Pripyat-Dnieper-Donets rift zone in the south of ...
E. V. Yutkina   +5 more
doaj   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

open access: yesAdvanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais   +32 more
wiley   +1 more source

Overcoming Interfacial Hurdles in Solid‐State Aluminum Batteries for Safe and Energy‐Dense Storage

open access: yesAdvanced Science, EarlyView.
Solid‐state aluminum batteries (SSABs) promise high energy density and intrinsic safety but face severe solid–solid interfacial challenges. This review reveals the three core hurdles—anode passivation, cathode contact loss, and electrolyte grain boundary resistance and discusses strategies including artificial interphases, alloying, and composite ...
Yunlei Wang   +5 more
wiley   +1 more source

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