Results 61 to 70 of about 10,822 (239)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Qualidade de ameixas (Primus salicina, Lindl.) 'Reubennel' após armazenamento refrigerado Quality of plums (Prunus salicina, Lindl) 'Reubennel' after cold storage

open access: yesScientia Agricola, 1995
O objetivo do trabalho foi verificar a qualidade de ameixas 'Reubemier após 30 e 40 dias de armazenagem a 0°C e 90-95% UR e 1, 2 e 3 dias de comercialização simulada em temperatura ambiente (25-26°C).
R.A. Kluge   +3 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Modification of the existing maximum residue levels for cyflufenamid in stone fruits and globe artichokes

open access: yesEFSA Journal, 2016
In accordance with Article 6 of Regulation (EC) No 396/2005, the evaluating Member State (EMS), Greece, received an application from Nisso Chemical Europe GmbH to modify the existing maximum residue levels (MRLs) for the active substance cyflufenamid in ...
European Food Safety Authority (EFSA)
doaj   +1 more source

Possibilities of plum cultivation in the Republic of Serbia [PDF]

open access: yesEkonomika Poljoprivrede (1979), 2015
Cultivation of plums has always been one of the most important parts of Serbian agriculture. In modern Serbian history cultivation of plums is among main parts of it's economy, being one of the first export products of modern Serbia.
Matković Milutin
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Bulletin: Number 498: Stocks for Plums [PDF]

open access: yes, 1923
25 pages, 1 article*Stocks for Plums* (Hedrick, U.
Hedrick, U. P.   +1 more
core   +3 more sources

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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