Results 41 to 50 of about 69,541 (306)
The Expressive Case against Plurality Rule [PDF]
, 2019 The U.S. election in November 2016 raised and amplified doubts about first-past-the-post (“plurality rule”) electoral systems. Arguments against plurality rule and for alternatives like preferential voting tend to be consequentialist: it is argued that ...
Wodak, Daniel, Daniel Wodak
core +2 more sources
Unexpected agreement in Spanish revisited
Glossa, 2018 Verbal agreement in Spanish is materialized as the rightmost morpheme on a verb. When enclitics attach, the expected order is: verbal base + AGR(eement) + CL(itic): hága-nAGR-loCL ‘Do it!’.
María Mare
doaj +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Logic of Non-Oppositional Selfhood: How to Remain Free from Dichotomies While Still Using Them
Open PhilosophyIn recent years, increasing philosophical attention has been given to an approach that does not begin with self and other as separated individuals, but rather takes relationality as the starting point for thinking about self and other.
Taguchi Shigeru
doaj +1 more source
Methodological Pluralism and Pluralism of Method [PDF]
, 1997 Pluralism is the philosophical position that the ultimate reality of the universe consists of a plurality of entities; it is an ontological position. But the concept of pluralism can be applied at a variety of levels: to the (epistemological) understanding of reality (whether its ultimate nature is a plurality or not), to the methods employed to ...
openaire +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
, 2018 Michif has two different morphological exponents of plurality: the French-derived article lii and the Cree-derived suffix -a/-ak. This chapter investigates the syntax and the semantics of both plural markers, and shows that the two plurals cannot occupy ...
Nicole Rosen, Carrie Gillon
core +1 more source
The Gift of Insanity. The Rise and Fall of Cultures from a Psychiatric Perspective
Eidos. A Journal for Philosophy of Culture, 2018 This paper argues in favor of two related theses. First, due to a fundamental, biologically grounded world-openness, human culture is a biological imperative.
Marcin Moskalewicz +2 more
doaj +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source