Results 51 to 60 of about 69,541 (306)
On stable outcomes of approval, plurality, and negative plurality games
, 2015 We prove two results on the generic determinacy of Nash equilibrium in voting games. The first one is for negative plurality games. The second one is for approval games under the condition that the number of candidates is equal to three.
DE SINOPOLI, FRANCESCO +2 more
core +1 more source
Moderating Political Extremism: Single Round vs Runoff Elections under Plurality Rule [PDF]
We compare single ballot vs dual ballot elections under plurality rule, assuming sincere voting and allowing for partly endogenous party formation.
Guido Tabellini, Massimo Bordignon
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
From plurality rule to proportional representation
, 2010 I consider the decision of a parliament that might change the electoral system from the plurality rule to proportional representation for forthcoming elections. Parties are office-motivated.
Ergun, Selim Jürgen
core +1 more source
Diaphonic pluralism: from truth pluralism to disagreement pluralism
Synthese, 2022 AbstractIn this paper, I offer a pluralistic framework for disagreement and I develop a strategy to account for the varieties of disagreement on the basis of the varieties of the truth across different domains of discourse. Truth-pluralism is thus sufficient for delivering pluralism about disagreement—that is, diaphonic pluralism.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Plurality of Cases – Plurality of Values
Changing Societies & Personalities, 2021 Elena A. Stepanova
doaj +1 more source