Results 231 to 240 of about 1,024,717 (349)

Induced Pluripotent Stem Cells (iPSC) and Their Use in Disease Modeling. [PDF]

Cureus
Dorota A, Maryniak N, Mariankowska A, Milczarek C, Dorota M, Zywiec W, Kozlowski K, Koval I, Czyzewski B, Czyzewska J.   +9 more
europepmc   +1 more source

Harnessing Cellular Feeling: Epigenetic to Mechanical Memory as a Framework for Stem Cell Manufacturing

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Stem cell‐based therapies hold transformative potential for regenerative medicine, yet their progress is constrained by persistent variability in manufacturing and clinical performance. Conventional frameworks such as Quality by Design (QbD), though effective for drugs and biologics, struggle to accommodate the dynamic nature of living cell ...
Mee‐Hae Kim, Masahiro Kino‐oka
wiley   +1 more source

Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.

Cell Stem Cell, 2017
Anjali Jacob, Anjali Jacob, M. Morley, F. Hawkins, F. Hawkins, Katherine B Mccauley, Katherine B Mccauley, J. Jean, J. Jean, Hillary S. Heins, Cheng-Lun Na, T. Weaver, Marall Vedaie, Marall Vedaie, K. Hurley, K. Hurley, A. Hinds, S. Russo, S. Kook, W. Zacharias, M. Ochs, Katrina E. Traber, L. Quinton, A. Crane, B. Davis, F. White, J. Wambach, J. Whitsett, F. S. Cole, E. Morrisey, S. Guttentag, M. Beers, D. N. Kotton, D. N. Kotton   +33 more
semanticscholar   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

Nature, 2011
R. Lister, Mattia Pelizzola, Yasuyuki S. Kida, R. D. Hawkins, Joseph R. Nery, G. Hon, Jessica Antosiewicz-Bourget, Jessica Antosiewicz-Bourget, Ronan C. O’Malley, R. Castanon, Sarit A. Klugman, M. Downes, R. Yu, Ron Stewart, Ron Stewart, Bing Ren, Bing Ren, J. Thomson, R. Evans, J. Ecker   +19 more
semanticscholar   +1 more source

Benchmarking and optimizing Perturb-seq in differentiating human pluripotent stem cells. [PDF]

Stem Cell Reports
Sivakumar S, Wang Y, Goetsch SC, Pandit V, Wang L, Zhao H, Sundarrajan A, Armendariz D, Takeuchi C, Deng M, Nzima M, Chen WC, Dederich AE, El Hayek L, Gao T, Gogate A, Kaur K, Kim HB, McCoy MK, Niederstrasser H, Oura S, Pinzon-Arteaga CA, Sanghvi M, Schmitz DA, Yu L, Zhang Y, Zhou Q, Kraus WL, Xu L, Wu J, Posner BA, Chahrour MH, Hon GC, Munshi NV.   +33 more
europepmc   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Generation of thymus-reconstituting T cell progenitors from human pluripotent stem cells. [PDF]

Cell Rep Methods
Philonenko ES, Zhang B, Albert E, Shah Z, Maksimov D, Shu Y, Li P, Volchkov P, Samokhvalov IM.   +8 more
europepmc   +1 more source

Drug‐coated balloons: From conventional designs to next‐generation innovations in vascular therapy

BMEMat, EarlyView.
This review traces the evolution of drug‐coated balloons (DCBs) from conventional designs to next‐generation platforms. We highlight innovations in balloon engineering, coating technologies, and therapeutic agents that enhance localized drug delivery while addressing challenges in efficiency, safety, and biocompatibility for vascular and emerging non ...
Lu Zhang, Jiawei Cui, Jin Wang, Manfred F. Maitz, Rifang Luo, Yunbing Wang   +5 more
wiley   +1 more source

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

Science, 2008
K. Okita, M. Nakagawa, Hong Hyenjong, T. Ichisaka, S. Yamanaka   +4 more
semanticscholar   +1 more source