Results 351 to 360 of about 980,977 (401)

Pluripotent Stem Cells

2014
Embryonic stem cells (ESCs) are pluripotent stem cells that are derived from early embryos. Induced pluripotent stem cells (iPSCs) are somatic cell-derived reprogrammed cells that have equivalent characteristics to ESCs. Disease-specific iPSCs have started to be used for the investigation of and development of the treatment for several diseases.
Tatsunori Sakamoto, Koji Nishimura, Hiroe Ohnishi, Takehiro Iki   +3 more
openaire   +1 more source

Characterization of pluripotent stem cells

Nature Protocols, 2013
Characterization of pluripotent stem cells is required for the registration of stem cell lines and allows for an impartial and objective comparison of the results obtained when generating multiple lines. It is therefore crucial to establish specific, fast and reliable protocols to detect the hallmarks of pluripotency.
Mercè, Martí, Lola, Mulero, Cristina, Pardo, Cristina, Morera, Meritxell, Carrió, Leopoldo, Laricchia-Robbio, Concepcion Rodriguez, Esteban, Juan Carlos, Izpisua Belmonte   +7 more
openaire   +2 more sources

Chemical reprogramming of human somatic cells to pluripotent stem cells

Nature, 2022
Jingyang Guan, Guan Wang, Jinlin Wang, Zhengyuan Zhang, Yao Fu, Lin Cheng, G. Meng, Yulin Lyu, Jialiang Zhu, Yanqin Li, Yang Wang, Shi Liuyang, Bei Liu, Zirun Yang, Huanjing He, Xinxing Zhong, Qijing Chen, Xu Zhang, Shicheng Sun, Weifeng Lai, Yan Shi, Lulu Liu, Lipeng Wang, Cheng Li, Shichun Lu, Hongkui Deng   +25 more
semanticscholar   +1 more source

Pluripotent Stem Cells for Cell Therapy

2021
In an increasingly geriatric population, in which elderly people frequently face chronic diseases and degenerative conditions, cell therapies as part of novel regenerative medicine approaches are of great interest. Even though today's cell therapies mostly rely on adult stem cells like the mesenchymal stem cells or primary somatic cells, pluripotent ...
openaire   +2 more sources

Pluripotent Stem Cells in Mice

2012
Pluripotent stem cells are able to self-renew and to differentiate into all adult cell types. Many studies report data describing these cells and characterize them in molecular terms. Gene expression data of pluripotent and non-pluripotent cells from mouse were assembled.
Rainer, Schmidt, Lena, Scheubert, Mitja, Lustrek, Dirk, Repsilber, Georg, Fuellen   +4 more
openaire   +2 more sources

Blastocyst-like structures generated from human pluripotent stem cells

Nature, 2021
Leqian Yu, Yulei Wei, Jialei Duan, Daniel A. Schmitz, M. Sakurai, Lei Wang, Kunhua Wang, Shuhua Zhao, G. Hon, Jun Wu   +9 more
semanticscholar   +1 more source

Pluripotent Stem Cells from Germ Cells

2006
To date, stem cells have been derived from three sources of germ cells. These include embryonic germ cells (EGCs), embryonal carcinoma cells (ECCs), and multipotent germ line stem cells (GSCs). EGCs are derived from primordial germ cells that arise in the late embryonic and early fetal period of development.
Candace L, Kerr, Michael J, Shamblott, John D, Gearhart   +2 more
openaire   +2 more sources

Mouse-Induced Pluripotent Stem Cells

2012
Pluripotent stem cells belong to a unique population of cells, which can self-renew indefinitely and have the potential to give rise to all cell types in an organism. Generally, pluripotent stem cells include embryonic stem cells (ESCs), embryonic germ cells (EGCs), and embryonal carcinoma cells (ECCs) (Boiani and Scholer 2005).
Hui, Zhang, Ying, Jin
openaire   +2 more sources

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

Science, 2007
Junying Yu, M. Vodyanik, K. Smuga-Otto, Jessica Antosiewicz-Bourget, Jennifer L. Frane, Shulan Tian, Jeff Nie, Gudrun A. Jonsdottir, Victor Ruotti, R. Stewart, I. Slukvin, J. Thomson   +11 more
semanticscholar   +1 more source

Generation of germline-competent induced pluripotent stem cells

Nature, 2007
K. Okita, T. Ichisaka, S. Yamanaka
semanticscholar   +1 more source