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ETV2 mediated differentiation of human pluripotent stem cells results in functional endothelial cells for engineering advanced vascularized microphysiological models

Zhang S, Wan Z, Wang L, Wu C, Zhang J, Spitz S, Wang X, Floryan MA, Coughlin MF, Pramotton FM, Xu L, Weiss R, Kamm RD.   +12 more
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Extracellular vesicles derived from induced pluripotent stem cells mediate anti- inflammatory effects in primary human macrophages

Fitzsimons S, Oggero S, Dillon ET, Martín MM, Clerkin S, Kennedy C, Davis J, Andrews D, Crean J, Belton O.   +9 more
europepmc   +1 more source

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Pluripotency of embryonic stem cells

Cell and Tissue Research, 2007
Embryonic stem (ES) cells derived from pre-implantation embryos have the potential to differentiate into any cell type derived from the three germ layers of ectoderm (epidermal tissues and nerves), mesoderm (muscle, bone, blood), and endoderm (liver, pancreas, gastrointestinal tract, lungs), including fetal and adult cells.
Yamanaka, S, Li, J, Kania, G, Elliott, S, Wersto, RP, Van Eyk, J, Wobus, AM, Boheler, KR   +7 more
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Pluripotent Stem Cells in Mice

2012
Pluripotent stem cells are able to self-renew and to differentiate into all adult cell types. Many studies report data describing these cells and characterize them in molecular terms. Gene expression data of pluripotent and non-pluripotent cells from mouse were assembled.
Dirk Repsilber, Georg Fuellen, Mitja Luštrek, Lena Scheubert, Rainer Schmidt   +4 more
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Induced Pluripotent Stem Cells

2010
Reprogramming of mouse and human somatic cells into induced pluripotent stem (iPS) cells has been possible with retroviral expression of the pluripotency-associated transcription factors Oct4, Sox2, Nanog, and Lin28 as well as Klf4 and c-Myc. iPS cells hold great potential as a model for diseases from the perspective of the individual patient and as an
Holm Zaehres, Hans R. Schöler, Jeong Beom Kim, Jeong Beom Kim   +3 more
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Induced pluripotent stem cells

Russian Journal of Genetics, 2009
Induced pluripotent stem cells (iPS) result from a reprogramming of somatic cells via transduction with viral vectors expressing the Oct4, Sox2, c-Myc, Klf4, Nanog, and Lin28 genes, which are essential for the establishment and maintenance of the pluripotent state. In properties, iPS are almost fully similar to embryonic stem cells (ESC).
Sergey P. Medvedev, Suren M. Zakian, N. A. Mazurok, Alexander I. Shevchenko   +3 more
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Pluripotent stem cells in rabbits.

2021
International ...
Afanassieff, Marielle, Honda, Arata, Gocza, Elen, Bosnakovski, Darko, Savatier, Pierre   +4 more
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Characterization of pluripotent stem cells

Nature Protocols, 2013
Characterization of pluripotent stem cells is required for the registration of stem cell lines and allows for an impartial and objective comparison of the results obtained when generating multiple lines. It is therefore crucial to establish specific, fast and reliable protocols to detect the hallmarks of pluripotency.
Leopoldo Laricchia-Robbio, Mercè Martí, Lola Mulero, Meritxell Carrió, Cristina Morera, Cristina Pardo, Concepcion Rodriguez Esteban, Juan Carlos Izpisua Belmonte   +7 more
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Cryobanking Pluripotent Stem Cells

2017
Cryobanking human pluripotent stem cells (hPSCs), be they human embryonic (hESCs) or induced pluripotent stem cells (iPSCs), is essential for their use in research and cell-based therapeutics. Working and master cell banks can be generated with a desired level of quality assurance applied during cell freezing and storage. Conventional vitrification has
Tenneille Ludwig, Eva Tomaskovic-Crook, Jeremy M. Crook, Jeremy M. Crook   +3 more
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