In the light of the emerging bacterial resistance to broad-spectrum antibiotics, the search for new antibacterial therapeutics and drug combinations is one of the most challenging topics nowadays.
Maya Margaritova Zaharieva +9 more
doaj +1 more source
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo +5 more
wiley +1 more source
SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl +11 more
wiley +1 more source
Binary systems of Brij® surfactants with Pluronic® F127 as griseofulvin carrier
The binary mixtures of Brij® surfactant and Pluronic® F127 were studied as carriers of griseofulvin. The F127 systems and Brij® 78 (C18H37E20), Brij® 98 (C18H35E20) and Brij® 700 (C18H37E100) were prepared in the proportions 10/90, 30/70, 50/50 and 70/30,
Ethanielda de L. Coelho +7 more
doaj +1 more source
Temperature Induced Gelation and Antimicrobial Properties of Pluronic F127 Based Systems. [PDF]
Lupu A, Rosca I, Gradinaru VR, Bercea M.
europepmc +1 more source
ABSTRACT In the process of myocardial cell structural and functional damage caused by various factors, current therapeutic strategies primarily focus on restoring myocardial blood supply, often neglecting the inherent complex microenvironment triggered by elevated reactive oxygen species (ROS) levels during myocardial injury.
Zhichao Liu +12 more
wiley +1 more source
Validated HPLC method for simultaneous quantitative determination of dimethylcurcumin and resveratrol in pluronic-F127 nanomicelles: Formulation with enhanced anticancer efficacy. [PDF]
Arakkunakorn W +6 more
europepmc +1 more source
Thermosensitive and photopolymerizable hydrogels based on Pluronic F127
Here it is reported the design, synthesis and characterization of new Pluronic® F127 derivatives, with the ability to form thermosensitive and photopolymerizable hydrogels. These active hydrogels undergo a sol-to-gel transition by increasing the temperature in a physiologically important temperature range thus resulting attractive for biomedical ...
Herrer Jiménez, Isabel Lucía +2 more
openaire +1 more source
Pluronic F127 and P104 Polymeric Micelles as Efficient Nanocarriers for Loading and Release of Single and Dual Antineoplastic Drugs. [PDF]
Gutiérrez-Saucedo RA +8 more
europepmc +1 more source
Hydrothermal effect of gunningite use Pluronic F127-Gelatin as template and the ibuprofen adsorption performance. [PDF]
Ulfa M +7 more
europepmc +1 more source

