In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery [PDF]
International Journal of Pharmaceutics, 2016 This study evaluated the use of Pluronic F127 and Pluronic F68 as excipients for formulating in situ gelling systems for ocular drug delivery. Thermal transitions have been studied in aqueous solutions of Pluronic F127, Pluronic F68 as well as their ...
Khateb, Kosai Al +6 more
core +5 more sources
Matrix-Dependent Stability and Antibacterial Efficacy of Silver Nanoparticles: A Comparative Study of Anionic Carbopol vs. Non-Ionic Pluronic Hydrogels [PDF]
PharmaceuticsBackground/Objectives: Hydrogels infused with silver nanoparticles (AgNPs) are widely used for their antibacterial properties, yet their stability, specifically upon contact with solid growth media (agar), remains poorly explored. This study compared two
Amane A. Alaroud +6 more
doaj +2 more sources
Polymeric Drug Delivery System Based on Pluronics for Cancer Treatment
Molecules, 2021 Pluronic polymers (pluronics) are a unique class of synthetic triblock copolymers containing hydrophobic polypropylene oxide (PPO) and hydrophilic polyethylene oxide (PEO) arranged in the PEO-PPO-PEO manner.
Jialin Yu +4 more
doaj +1 more source
Pharmaceutics, 2023 A keloid is a benign tumor manifested as abnormal fibroplasia on the surface of the skin. Curing keloids has become a major clinical challenge, and searching for new treatments and medications has become critical.
Hongshuang Wan +12 more
doaj +1 more source
Effect of Pluronic Introduction to Polycaprolactone Substrate on the Blend Hydrophilicity by Molecular Dynamic Simulation [PDF]
علوم و تکنولوژی پلیمر, 2016 Poly()ε-caprolactone) ()PCL) has been widely investigated for medical applications because of its good physicochemical properties; however hydrophobic nature of PCL has been a colossal obstacle toward achieving scaffolds which offer satisfactory cell ...
Mohammad Masoud Mirhosseini +2 more
doaj +1 more source
Pharmaceutics, 2021 The outer part of the retina pigment epithelium (RPE) in the retina is the main site of neovascularization associated with retinal diseases. However, various obstacles interrupt the delivery of medicines across the RPE, mainly due to the well-developed ...
Kiyoon Kwon +3 more
doaj +1 more source
Chitosan/Pluronic F127 Thermosensitive Hydrogel as an Injectable Dexamethasone Delivery Carrier
Gels, 2022 Intra-articular administration of anti-inflammatory drugs is a strategy that allows localized action on damaged articular cartilage and reduces the side effects associated with systemic drug administration.
Jomarien García-Couce +5 more
doaj +1 more source
Loading of hydrophobic drug silymarin in pluronic and reverse pluronic mixed micelles
Journal of Drug Delivery Science and Technology, 2022 In the presented work, pure pluronic and mixed micelles of normal pluronics (F108, F127, P85 and P84) with reverse pluronic (10R5) have been studied to enhance the solubilization of the hydrophobic drug silymarin (SLY) at different % w/v proportions (4:1, 2.5, 1:4 and 5).
Saweta Garg +3 more
openaire +2 more sources
Masculinizing Effects of Chrysin-Loaded Poloxamer Micelles on Siamese Fighting Fish
Veterinary Sciences, 2021 Siamese fighting fish (Betta splendens) are freshwater fish that are commonly found in Thailand and other Southeast Asian countries. In the present study, chrysin-loaded polymeric micelles (CPs) were developed and investigated for the masculinizing ...
Nattakanwadee Khumpirapang +4 more
doaj +1 more source
Effects of Liposomes Contained in Thermosensitive Hydrogels as Biomaterials Useful in Neural Tissue Engineering [PDF]
, 2017 Indexación: Scopus.Advances in the generation of suitable thermosensitive hydrogels for the delivery of cells in neural tissue engineering demonstrate a delicate relationship between physical properties and capabilities to promote cell proliferation and ...
Acevedo, C. +7 more
core +6 more sources