Results 1 to 10 of about 16,822 (237)

Gelation Behaviour of Pluronic F127/Polysaccharide Systems Revealed via Thioflavin T Fluorescence [PDF]

Gels, 2023
Fast, reliable methods for characterizing the micelle-to-gel transition in emerging Pluronic F127/polysaccharide materials are essential for tailoring their applications as in situ gelling delivery systems.
George-Alin Balan, Aurica Precupas, Iulia Matei   +2 more
doaj   +2 more sources

Progress in Pluronic F127 Derivatives for Application in Wound Healing and Repair [PDF]

International Journal of Nanomedicine, 2023
Shanshan Li,1,* Cheng Yang,1,* Junqiang Li,1,* Chao Zhang,1 Liaoliao Zhu,1 Yang Song,1 Yongdong Guo,1 Ronglin Wang,1 Dongxue Gan,1 Jingjie Shi,1 Peixiang Ma,1 Fei Gao,2 Haichuan Su1 1Department of Oncology, The Second Affiliated Hospital, Air
Li S, Yang C, Li J, Zhang C, Zhu L, Song Y, Guo Y, Wang R, Gan D, Shi J, Ma P, Gao F, Su H   +12 more
doaj   +2 more sources

Pluronic F127 "nanoarmor" for stabilization of Cowpea mosaic virus immunotherapy. [PDF]

Bioeng Transl Med, 2023
AbstractOur lab demonstrated that intratumoral Cowpea mosaic virus (CPMV) is a potent antitumor immunotherapy when used as in situ vaccine. As we pave the way for human clinical translation, formulation chemistry needs to be optimized for long‐term storage of the drug candidate. In this work, CPMV was nanoengineered with Pluronic F127 to realize liquid
Shin MD, Jung E, Moreno-Gonzalez MA, Ortega-Rivera OA, Steinmetz NF.   +4 more
europepmc   +4 more sources

Visualization of supramolecular structure of Pluronic F127 micellar hydrogels using cryo-TEM [PDF]

MethodsX, 2020
Pluronic® F127 micellar hydrogels are of growing interest to the biomedical field due to their versatility as drug delivery systems. Pluronic® F127 is a symmetric and amphiphilic triblock copolymer which in aqueous medium self-assembles into micelles ...
Laura C.E. da Silva, Antonio C. Borges, Marcelo G. de Oliveira, Marcelo A. de Farias   +3 more
doaj   +2 more sources

In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery [PDF]

International Journal of Pharmaceutics, 2016
This study evaluated the use of Pluronic F127 and Pluronic F68 as excipients for formulating in situ gelling systems for ocular drug delivery. Thermal transitions have been studied in aqueous solutions of Pluronic F127, Pluronic F68 as well as their ...
Khateb, Kosai Al, Khutoryanskiy, Vitaliy V., Lau, Wing Man, Mussin, Marat N., Ozhmukhametova, Elvira K., Rakhypbekov, Tolebai K., Seilkhanov, Serzhan K.   +6 more
core   +5 more sources

Chitosan/Pluronic F127 Thermosensitive Hydrogel as an Injectable Dexamethasone Delivery Carrier. [PDF]

Gels, 2022
Intra-articular administration of anti-inflammatory drugs is a strategy that allows localized action on damaged articular cartilage and reduces the side effects associated with systemic drug administration. The objective of this work is to prepare injectable thermosensitive hydrogels for the long-term application of dexamethasone.
García-Couce J, Tomás M, Fuentes G, Que I, Almirall A, Cruz LJ.   +5 more
europepmc   +6 more sources

Co-delivery of NGF and BMP-2 via thermosensitive pluronic F127 hydrogel enhances chondrogenesis and cartilage repair [PDF]

Scientific Reports
Cartilage defects are difficult to repair due to the tissue’s avascular nature, low cell density, and limited regenerative capacity. Growth factor–based tissue engineering offers a promising strategy for enhancing cartilage regeneration. This study aimed
Yue Huang, Bin Shi, Yunyang Liao, Gengsen Zou, Kun Song   +4 more
doaj   +2 more sources

Nanotechnology-Driven Strategy Against SARS-CoV-2: Pluronic F127-Based Nanomicelles with or Without Atazanavir Reduce Viral Replication in Calu-3 Cells [PDF]

Viruses
Despite extensive efforts, no highly effective antiviral molecule exists for treating moderate and severe COVID-19. Nanotechnology has emerged as a promising approach for developing novel drug delivery systems to enhance antiviral efficacy.
Eduardo Ricci-Junior, Alice Santos Rosa, Tatielle do Nascimento, Ralph Santos-Oliveira, Marcos Alexandre Nunes da Silva, Debora Ferreira Barreto-Vieira, Luísa Tozatto Batista, Giovanna Barbosa da Conceição, Tayane Alvites Nunes Quintão, Vivian Neuza Santos Ferreira, Milene Dias Miranda   +10 more
doaj   +2 more sources

Improved permeation performance and fouling-resistance of Poly(vinyl chloride)/Polycarbonate blend membrane with added Pluronic F127 [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2014
The aim of this work was to prepare and characterize poly(vinyl chloride) (PVC)/polycarbonate (PC) blend membranes for use in ultrafiltration. Pluronic F127 was used as an additive to modify the membrane surface of the PVC/PC blended membranes. The PVC/
Supateekan Pacharasakoolchai, Watchanida Chinpa   +1 more
doaj   +2 more sources

Matrix-Dependent Stability and Antibacterial Efficacy of Silver Nanoparticles: A Comparative Study of Anionic Carbopol vs. Non-Ionic Pluronic Hydrogels [PDF]

Pharmaceutics
Background/Objectives: Hydrogels infused with silver nanoparticles (AgNPs) are widely used for their antibacterial properties, yet their stability, specifically upon contact with solid growth media (agar), remains poorly explored. This study compared two
Amane A. Alaroud, Suhad Bani Melhim, Fahmy Banat, Arshiya Husaini, Suha M. Abudoleh, Mahmoud Y. Alkawareek, Alaaldin M. Alkilany   +6 more
doaj   +2 more sources