Results 1 to 10 of about 8,831 (205)

Progress in Pluronic F127 Derivatives for Application in Wound Healing and Repair [PDF]

open access: yesInternational Journal of Nanomedicine, 2023
Shanshan Li,1,* Cheng Yang,1,* Junqiang Li,1,* Chao Zhang,1 Liaoliao Zhu,1 Yang Song,1 Yongdong Guo,1 Ronglin Wang,1 Dongxue Gan,1 Jingjie Shi,1 Peixiang Ma,1 Fei Gao,2 Haichuan Su1 1Department of Oncology, The Second Affiliated Hospital, Air
Li S   +12 more
doaj   +6 more sources

Gelation Behaviour of Pluronic F127/Polysaccharide Systems Revealed via Thioflavin T Fluorescence [PDF]

open access: yesGels, 2023
Fast, reliable methods for characterizing the micelle-to-gel transition in emerging Pluronic F127/polysaccharide materials are essential for tailoring their applications as in situ gelling delivery systems.
George-Alin Balan   +2 more
doaj   +2 more sources

Visualization of supramolecular structure of Pluronic F127 micellar hydrogels using cryo-TEM [PDF]

open access: yesMethodsX, 2020
Pluronic® F127 micellar hydrogels are of growing interest to the biomedical field due to their versatility as drug delivery systems. Pluronic® F127 is a symmetric and amphiphilic triblock copolymer which in aqueous medium self-assembles into micelles ...
Laura C.E. da Silva   +3 more
doaj   +2 more sources

Co-delivery of NGF and BMP-2 via thermosensitive pluronic F127 hydrogel enhances chondrogenesis and cartilage repair [PDF]

open access: yesScientific Reports
Cartilage defects are difficult to repair due to the tissue’s avascular nature, low cell density, and limited regenerative capacity. Growth factor–based tissue engineering offers a promising strategy for enhancing cartilage regeneration. This study aimed
Yue Huang   +4 more
doaj   +2 more sources

Nanotechnology-Driven Strategy Against SARS-CoV-2: Pluronic F127-Based Nanomicelles with or Without Atazanavir Reduce Viral Replication in Calu-3 Cells [PDF]

open access: yesViruses
Despite extensive efforts, no highly effective antiviral molecule exists for treating moderate and severe COVID-19. Nanotechnology has emerged as a promising approach for developing novel drug delivery systems to enhance antiviral efficacy.
Eduardo Ricci-Junior   +10 more
doaj   +2 more sources

Study in vivo intraocular biocompatibility of in situ gelation hydrogels: poly(2-ethyl oxazoline)-block-poly(ε-caprolactone)-block-poly(2-ethyl oxazoline) copolymer, matrigel and pluronic F127. [PDF]

open access: yesPLoS ONE, 2013
The long term in vivo biocompatibility is an essential feature for the design and development of sustained drug release carriers. In the recent intraocular drug delivery studies, hydrogels were suggested as sustained release carriers.
Yih-Shiou Hwang   +6 more
doaj   +1 more source

Synthesis and Optimization of Next-Generation Low-Molecular-Weight Pentablock Copolymer Nanoadjuvants

open access: yesVaccines, 2023
Polymeric nanomaterials such as Pluronic®-based pentablock copolymers offer important advantages over traditional vaccine adjuvants and have been increasingly investigated in an effort to develop more efficacious vaccines.
Alaric C. Siddoway   +3 more
doaj   +1 more source

Effect of tocopherol on Pluronic microemulsions: turbidity studies and Dynamic light scattering and dynamic surface tension measurements [PDF]

open access: yesNanomedicine Research Journal, 2018
The development and design of the biocompatible and biodegradable thermodynamically stable micellar and microemulsion transparent dispersions to reduce the free and unbounded drugs concentration in the blood is a basic challenge in field of drug efficacy
Abbas Rahdar
doaj   +1 more source

Vocal fold augmentation with injectable polycaprolactone microspheres/pluronic F127 hydrogel: long-term in vivo study for the treatment of glottal insufficiency. [PDF]

open access: yesPLoS ONE, 2014
There is increasing demand for reconstruction of glottal insufficiency. Several injection materials have been examined for this purpose, but all had limitations, such as poor long-term durability, migration from the injection site, inflammation ...
Seong Keun Kwon   +8 more
doaj   +1 more source

Balance of Drug Residence and Diffusion in Lacrimal Fluid Determine Ocular Bioavailability in In Situ Gels Incorporating Tranilast Nanoparticles

open access: yesPharmaceutics, 2021
We previously designed ophthalmic formulations (nTRA) containing tranilast nanoparticles (Tra-NPs) with high uptake into ocular tissues. In this study, we used in situ gel (ISG) bases comprising combinations of pluronic F127 (F127) and methylcellulose ...
Misa Minami   +6 more
doaj   +1 more source

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