Results 11 to 20 of about 8,831 (205)

Chitosan/Pluronic F127 Thermosensitive Hydrogel as an Injectable Dexamethasone Delivery Carrier. [PDF]

open access: yesGels, 2022
Intra-articular administration of anti-inflammatory drugs is a strategy that allows localized action on damaged articular cartilage and reduces the side effects associated with systemic drug administration. The objective of this work is to prepare injectable thermosensitive hydrogels for the long-term application of dexamethasone.
García-Couce J   +5 more
europepmc   +6 more sources

Formulation of Nanomicelles Loaded with Cannabidiol as a Platform for Neuroprotective Therapy

open access: yesPharmaceutics, 2022
The present study is focused on the development of cannabidiol-loaded polymeric nanomicelles as a drug delivery system with neuroprotective effects.
Yordan Yordanov   +6 more
doaj   +1 more source

Numerical investigation of moving gel wall formation in a Y-shaped microchannel

open access: yesSN Applied Sciences, 2023
Molecular diffusive membranes play crucial roles in the field of microfluidics for biological applications e.g., 3D cell culture and biosensors. Hydrogels provide a range of benefits such as free diffusion of small molecules, cost-effectiveness, and the ...
Donya Dabiri   +3 more
doaj   +1 more source

Pluronic F127 "nanoarmor" for stabilization of Cowpea mosaic virus immunotherapy. [PDF]

open access: yesBioeng Transl Med, 2023
AbstractOur lab demonstrated that intratumoral Cowpea mosaic virus (CPMV) is a potent antitumor immunotherapy when used as in situ vaccine. As we pave the way for human clinical translation, formulation chemistry needs to be optimized for long‐term storage of the drug candidate. In this work, CPMV was nanoengineered with Pluronic F127 to realize liquid
Shin MD   +4 more
europepmc   +4 more sources

Battling Biofilm Forming Nosocomial Pathogens Using Chitosan and Pluronic F127

open access: yesJournal of Pure and Applied Microbiology, 2020
Biofilm represents a potential strut in bacterial treatment failure. It has a dual action; it affords microbial resistance against antibiotics and facilitate transmission of pathogenic bacteria.
Doaa Eid   +3 more
doaj   +1 more source

Injectable Composite Systems of Gellan Gum:Alginate Microparticles in Pluronic Hydrogels for Bioactive Cargo Controlled Delivery: Optimization of Hydrogel Composition based on Rheological Behavior

open access: yesFluids, 2022
Due to the high complexity of some treatments, there is a need to develop drug-delivery systems that can release multiple drugs/bioactive agents at different stages of treatment.
Henrique Carrêlo   +4 more
doaj   +1 more source

The development and study of novel membrane materials based on polyphenylene isophthalamide - Pluronic F127 composite

open access: yesMaterials & Design, 2019
In the present study, novel pervaporation (nonporous, dense) and ultrafiltration (porous) membranes based on polyphenylene isophthalamide (PA) modified by Pluronic F127 (up to 20 wt%) used as a modifier and a pore-forming agent were developed and ...
M.E. Dmitrenko   +7 more
doaj   +1 more source

Thermal, spectroscopic, and dissolution studies of ketoconazole–Pluronic F127 system [PDF]

open access: yesJournal of Thermal Analysis and Calorimetry, 2014
One strategy for improving the dissolution of poorly water soluble drugs is to prepare solid dispersions such as binary mixtures with hydrophilic carriers. These mixtures are generally characterized by better solubility than those of the individual components from which they are formed. In the present study, solid dispersions of ketoconazole (KET) with
Karolewicz, Bożena   +5 more
openaire   +2 more sources

Demulsifier-Inspired Superhydrophilic/Underwater Superoleophobic Membrane Modified with Polyoxypropylene Polyoxyethylene Block Polymer for Enhanced Oil/Water Separation Properties

open access: yesMolecules, 2023
Demulsifiers are considered the key materials for oil/water separation. Various works in recent years have shown that demulsifiers with polyoxypropylen epolyoxyethylene branched structures possess better demulsification effects. In this work, inspired by
Mengmeng Zhang   +8 more
doaj   +1 more source

Tough interpenetrating Pluronic F127/polyacrylic acid hydrogels

open access: yesPolymer, 2013
Abstract Tough interpenetrating polymer network (IPN) hydrogels with pH- and temperature sensitivity were prepared by crosslinking copolymerization of acrylic acid (AAc) and N,N′-methylenebis(acrylamide) in 20 w/v% aqueous solutions of F127 (PEO 99 -PPO 65 -PEO 99 ).
Baskan, Tuba   +2 more
openaire   +3 more sources

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