Results 41 to 50 of about 39,468 (302)

Extraction of polar and nonpolar biomarkers from the martian soil using aqueous surfactant solutions [PDF]

open access: yes, 2012
The Life Marker Chip intends to use an aqueous surfactant solution to extract both polar AND nonpolar biomarkers from the martian soil for transport to an antibody-based detection system. Currently, a solution of 1.5 g l-1 polysorbate 80 in 20:80 (vol:
Court, Richard W.   +4 more
core   +1 more source

Cell‐Free DNA as a Biomarker of Cell Death and Treatment Response for On‐Chip Three‐Dimensional Tumor Models

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents quantifying cell‐free DNA (cfDNA) as a non‐disruptive and rapidly quantifiable method for assessing cell death for on‐chip 3D sarcoma tumor models. On‐chip cfDNA release reflects tumor burden, extent of cell death, and survival of in vitro and ex vivo 3D models, providing valuable insight into the temporal response of tumor models ...
Maryam Ziaee   +7 more
wiley   +1 more source

In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery

open access: yes
This study evaluated the use of Pluronic F127 and Pluronic F68 as excipients for formulating in situ gelling systems for ocular drug delivery. Thermal transitions have been studied in aqueous solutions of Pluronic F127, Pluronic F68 as well as their ...
Seilkhanov SK   +6 more
core   +4 more sources

The Therapeutic Effect of Methotrexate-Conjugated Pluronic-Based Polymeric Micelles on the Folate Receptor-Rich Tumors Treatment [Retraction]

open access: yesInternational Journal of Nanomedicine, 2022
Chen Y, Zhang W, Huang Y, et al. Int J Nanomedicine. 2015;10:4043-4057. The Editor and Publisher of the International Journal of Nanomedicine wish to retract the published article.
Chen Y   +6 more
doaj  

Gelation Behaviour of Pluronic F127/Polysaccharide Systems Revealed via Thioflavin T Fluorescence

open access: yesGels, 2023
Fast, reliable methods for characterizing the micelle-to-gel transition in emerging Pluronic F127/polysaccharide materials are essential for tailoring their applications as in situ gelling delivery systems.
George-Alin Balan   +2 more
doaj   +1 more source

Protein‐Polymer Dynamic Hydrogels Utilizing Native Ligand Binding for Injectable Therapeutic Delivery and 3D Printing

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic nanocolloidal hydrogels were synthesized via the co‐assembly of ligand‐modified spheroidal hyperbranched poly(glycerol) (HPG) and soluble albumin nanoparticles (SANs). Co‐assembly occurred through self‐association of the HPG, as well as its interaction with SANs via native ligand binding.
S. Cem Millik   +9 more
wiley   +1 more source

DRUG RELEASE FROM PLURONIC GELS [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1994
The release rate of progesterone, dexamethasone, ethinylestradiol and a-methyldopa(MD) was determined in aqueous gels of pluronic surfactants (F-65, F-127, F-123) and the effects of concentration and temperature were investigated.
Salwa Safwat
doaj   +1 more source

Development of a Laponite Pluronic Composite for Foaming Applications [PDF]

open access: yes, 2012
The focus of the following research was to provide an optimized particle stabilized foam of Laponite and Pluronic L62 in water by understanding (1) the Laponite-Pluronic interactions and properties for improved performance in a particle stabilized foam ...
Davis, James William
core   +1 more source

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

open access: yesAdvanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar   +2 more
wiley   +1 more source

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

open access: yesAdvanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn   +17 more
wiley   +1 more source

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