Results 71 to 80 of about 5,618 (207)

Towards a rational design of solid drug nanoparticles with optimised pharmacological properties. [PDF]

, 2016
Solid drug nanoparticles (SDNs) are a nanotechnology with favourable characteristics to enhance drug delivery and improve the treatment of several diseases, showing benefit for improved oral bioavailability and injectable long-acting medicines.
Alexis, Baert, Bland, Bosgra, Breemen, Chiappetta, Cho, Costa, Crewe, Deschamps, Doh, Fernandez, Haessler, Ittrich, Jia, Joralemon, Kaminskas, Kettler, Klooster, Lee, Li, Liptrott, Lyseng-Williamson, Markowitz, Marrache, Martin, Mathaes, McDonald, McDonald, Moss, Moss, Ogburn, Ohtsuki, Ong, Portenoy, Poulin, Qhattal, Roche, Samtani, Sareen, Schrade, Siccardi, Sikarra, Smith, Spreen, Thakor, Togami, Vrouenraets, Ward, Weir, Wessler, Wu, Xue, Zhang, Zhang   +54 more
core   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Controlled Antibiotic Release From Emulsion‐Loaded Alginate and Fibrin Hydrogels Using Ultrasound

Journal of Biomedical Materials Research Part A, Volume 114, Issue 2, February 2026.
Schematic of ultrasound‐responsive VAN delivery from phase‐shift emulsion‐loaded alginate and fibrin hydrogels. Drug release was monitored over 7 days and quantified by spectrophotometry and antibacterial assays. Emulsion loading reduced burst release and enabled sustained baseline delivery, while ultrasound triggering enhanced VAN release and ...
Ziba Ghareh Nazi Fam, Asia Winslow, Mario L. Fabiilli, Sam Varghese, Brian E. Oeffinger, Flemming Forsberg, Noreen J. Hickok, Lauren J. Delaney   +7 more
wiley   +1 more source

Rational Design of Hyaluronic Acid-Based Copolymer-Mixed Micelle in Combination PD-L1 Immune Checkpoint Blockade for Enhanced Chemo-Immunotherapy of Melanoma

Frontiers in Bioengineering and Biotechnology, 2021
The application of combinational therapy breaks the limitation of monotherapy and achieves better clinical benefit for tumor therapy. Herein, a hyaluronic acid/Pluronic F68-based copolymer-mixed micelle was constructed for targeted delivery of ...
Chaopei Zhou, Xiuxiu Dong, Chunxiang Song, Shuang Cui, Tiantian Chen, Daji Zhang, Xiuli Zhao, Chunrong Yang   +7 more
doaj   +1 more source

Fluorofluorophores: Fluorescent Fluorous Chemical Tools Spanning the Visible Spectrum [PDF]

, 2014
“Fluoro” refers to both fluorescent and fluorinated compounds. Despite the shared prefix, there are very few fluorescent molecules that are soluble in perfluorinated solvents.
Ahrens E. T., Anton D., Biro G. P., Brittain S. M., Castro C. I., Chikamatsu M., Correa de Costa R., Curran D. P., De Luca G., DiMagno S. G., Ellen M. Sletten, Geyer R., Ghosh S. K., Gladysz J. A., Grosse A. V., Hird M., Horvath I. T., Horvath I. T., Hugel H. M., Huque F. T. T., Janjic J. M., Janjic J. M., Jiao H., Kelkar S. S., Kim S. H., Kolmel D. K., Krafft M. P., Lim Y. T., Lim Y. T., Liu C., Lowe K. C., Lu N., Matsubara H., Matsui M., Matsui M., McKeen L. W., Pohl N. L., Rapoport N., Reznik N., Riess J. G., Ruiz-Cabello J., Salwiczek M., Schmidt R., Schultz M. M., Simons J. H., Sloviter H. A., Srinivas M., Studer A., Sun H., Tadros T., Timothy M. Swager, Vincent J. M., Zhang W.   +52 more
core   +2 more sources

A Sensitive Reporter Mouse Model to Study Adipocyte‐Derived Extracellular Vesicles In Vivo

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
ABSTRACT Extracellular vesicles (EVs) affect the function of cells in living animals. Yet, cell type‐specific EV abundances and their distribution in biological fluids are technically challenging to study. Thus, we aimed to develop an in vivo EV reporter system to monitor cell‐type‐specific EVs, with a focus on adipocyte‐derived EVs.
Didde Riisager Hansen, Rugivan Sabaratnam, Lasse Bach Steffensen, Per Svenningsen   +3 more
wiley   +1 more source

Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity

Pharmaceutics, 2021
Although it is a front-line in tuberculosis treatment, rifampicin (RF) exhibits poor oral bioavailability and hepatotoxicity. Rectal mucoadhesive and in situ rectal gels were developed to overcome drug drawbacks.
Fakhria Al-Joufi, Mohammed Elmowafy, Nabil K. Alruwaili, Khalid S. Alharbi, Khaled Shalaby, Shakir D. Alsharari, Hazim M. Ali   +6 more
doaj   +1 more source

Advancing Single‐Walled Carbon Nanotubes toward Next‐Generation Electronic Materials: The Critical Roles of Purity and Processability

Small Methods, Volume 10, Issue 4, 23 February 2026.
Single‐walled carbon nanotubes (SWNTs) are promising for a wide range of applications. In particular, their exceptional electrical conductivity positions them as potential alternatives to traditional metal conductors. This review identifies the key mechanisms governing their conductivity within composites and proposes practical pathways for translating
Xiao Yu, Alex Adronov
wiley   +1 more source

Formulation, Colloidal Characterization, and In Vitro Biological Effect of BMP-2 Loaded PLGA Nanoparticles for Bone Regeneration

Pharmaceutics, 2019
Nanoparticles (NPs) based on the polymer poly (lactide-co-glycolide) acid (PLGA) have been widely studied in developing delivery systems for drugs and therapeutic biomolecules, due to the biocompatible and biodegradable properties of the PLGA.
Teresa del Castillo-Santaella, Inmaculada Ortega-Oller, Miguel Padial-Molina, Francisco O’Valle, Pablo Galindo-Moreno, Ana Belén Jódar-Reyes, José Manuel Peula-García   +6 more
doaj   +1 more source

Composite alginate and gelatin based bio-polymeric wafers containing silver sulfadiazine for wound healing [PDF]

, 2015
Lyophilized wafers comprising sodium alginate (SA) and gelatin (GE) (0/100, 75/25, 50/50, 25/75, 0/100 SA/GE, respectively) with silver sulfadiazine (SSD, 0.1% w/w) have been developed for potential application on infected chronic wounds.
Asane, Atiyeh, Ayensu, Aziz, Balakrishnam, Boanini, Boateng, Boateng, Boateng, Carter, Choi, Devi, Dong, Fajardo, Goh, Harshavardhan Pawar, Howard, Jiang, Joshua Boateng, Kuijpers, Li, Liu, Mogoşanua, Moura, Obinna Okeke, Panouille, Pawar, Pawar, Pereira, Rocio Burgos-Amador, Roy, Roy, Saarai, Saarai, Salamat-Miller, Singh, Thomas, Watson   +37 more
core   +1 more source